• Herbal products to help with ED associated with Peyronie's disease?

    I believe I got PD using ED drugs been married 30 yrs & need some erection help. Have stopped using the drugs, can you suggest something herbal I can use to replace them. Thanks Dave

    Greetings Dave,

    What you report is rather common.  I have communicated with hundreds of men who tell me their Peyronie's disease started after using PDE5 inhibitor drugs (Viagra, Cialis, Levitra); this can happen after just one use or repeated uses.  For more information see Peyronie's disease and Viagra, Levitra and Cialis and Peyronie's treatment and Cialis.

    If you go to the PDI shopping cart and scroll about 3/4 the way down until you see BetterMAN and about 5-6 other sex stimulant products. The most important of the group is a product called Stimulin. You would definitely want to include Stimulin with whatever else you use.  

    All of these herbal products are much more gentle than your drugs and will not worsen your PD problem.   Many men use them while undergoing their natural Peyronie's treatment plan.  TRH

    What is my opinion of prescription drug injection?

    What is the Dr's opinion on using the prescription Edex injected with a syringe? 

    Bryant from Ohio

     

    Greetings Bryant, 

    You ask for my opinion about Edex injections.  I will not comment on the drug, because that is the decision of your treating doctor.  But I will make a few observations about injections in general and how they could further injure the tunica albuginea.

    Anytime you inject ANYTHING – even sterile water – into the penis and directly or indirectly contact the delicate tunica albuginea, you are taking a serious risk of making your Peyronie's disease worse. This could either occur just from the simple act of piercing the tissue of the tunica albuginea, or the placement of a concentrated chemical that is foreign to that tissue, or both.

    I have communicated with many, many men whose Peyronie's disease started or was made worse from penile injections of a variety of substances.

    If your problem is PD, why are you taking an ED medication? Some MDs prescribe Viagra, Edex, etc to their PD patients in the belief that this increases the local circulation which in turn is beneficial to PD.

    What if you could take a drug that would enable you to lift a ton of weight above your head and keep it there for an hour? Nice trick, very impressive, but your body is not built to take that kind of pressure. It would cause great damage to internal organs, your spine, your blood vessels, all major joints, etc. Simply put, “It just ain’t natural.” Same with Viagra, Levitra or Cialis. The increased pressure created by these medications can be very damaging to the delicate tunica albuginea, and can result in or worsen a case of PD. What would happen to your car tires if you happened to over-inflate them with 100 pounds of air pressure, even though they were built to take just 40 pounds of pressure. You would be running the risk of damage to the internal structure of tire, wouldn’t you? Of course.

    The same thing can happen if the penis is over-inflated and then given a “rough ride.” This is where the problems start, and this is what I wanted to bring to your attention. It is very likely that the MDs who prescribe these medications to men with PD will not agree with this thinking. MDs tend to favor a chemical “fix” even if it is temporary, so you would tend to expect a prejudice from an MD to use drugs to solve most problems.

    A penis that is predisposed to PD in the first place cannot tolerate the kind of stress that these erections drugs create.  If you think independently and logically about what happens when these drugs are used, you should have no trouble understanding how this could work against you.  That is just the way I see it and I feel compelled to share this rationale with you. Use of Viagra and other related meds like it could easily be worsening the very problem you are attempting to heal. Something to think about.  TRH

    Pentoxifylline and Peyronie’s Disease Treatment

    Pentox for Peyronie’s treatment is an off-label use

    Every now and then I get an email asking for my opinion about using Pentox (Pentoxifylline) for Peyronie’s disease treatment.  Over time I have developed a few ideas about this controversial drug that is gaining some popularity as an off-label Peyronie’s treatment.

    Those MDs who prescribe Pentox are still trying to figure out the best way to use it, not only for PD but for many other conditions.  While the primary use for Pentoxifylline is based on its ability to increase peripheral blood circulation, hence it is used to treat senile dementia and intermittent claudication, Pentox is gaining acceptance with the medical community for Peyronie’s treatment.

    Some MDs who have learned the hard way that PDE5 drugs (Viagra, Cialis, Levitra) are not at all a safe or effective Peyronie’s treatment have instead begun to prescribe Pentox to increase blood flow in Peyronies.   But to have that make any sense at all you have to believe that PD is caused by reduced blood flow in the first place, or that merely increasing the blood flow will somehow help PD.  I can totally agree with that thinking if you have evidence that your penis suffers from reduced blood flow (it is cold and blue).  But if your penis is not cold and blue and bent, then you probably will not benefit from Pentox in the way that most people think.

    It is my opinion that when Pentox is said to help men with PD it is because as the blood flow is increased to the periphery, it also brings in an increased flow of nutrients to assist the healing process.  Further, when Pentox helps a case of PD it is because of the totally secondary benefit of increasing the body’s ability to heal and repair the PD plaque when there are more nutrients in an area of the body.   It is a small point, perhaps, but a vitally important point to understand that it all comes down to the body healing the PD scar – not the Pentox having some curative ability by itself.   If Pentoxifylline can increase general circulation more safely than Viagra, Cialis, and Levitra, then great I am all for that.  But you have to consider that if you do not have a circulatory problem in the first place, then why take any of these drugs at all?

    If the benefit of Pentox is to bring more nutrients into the tissues, to assist healing and repair of the PD plaque or scar, that is wonderful.  If it is beneficial to bring more nutrients into the tissue, would it not be a more logical and effective Peyronie’s treatment to intentionally and intelligently supply a wide variety of nutrients at a higher than average dosage to the body to assist the healing process?  After all, that is what PDI has been doing since 2002 and it works in a great percentage of cases when it is done correctly.

    Since extremely few men actually have any evidence of a circulatory problem in the pelvis, taking Pentox or even Viagra, Cialis, and Levitra, will not make a difference because that is not the problem that is going on with PD.   If the problem is that you did not heal your tunica albuginea injury because of poor nutrient availability then I suggest it would do you a lot of good to increase the nutrients directly, not indirectly by playing with the circulatory system when there is no circulatory problem.

    You notice that I do not say, “Do not take Pentox,” I only say it is new so use caution.  I also say that when Pentoxifylline helps it probably does so only because it helps the body work better by increasing available nutrients, not because it specifically increases blood flow.  If you want to help your pelvic blood flow:

    1.    Wear boxer shorts

    2.    Uncross your legs when you sit

    3.    Do some Kegel exercises

    4.    Put a moist hot pack on your privates when you watch TV

    Most MDs are taking the attitude that while they do not know if Pentox helps PD, or why it helps when it appears to help PD, at least they currently have no evidence that it makes PD worse – so what the hell, take it and let’s see what it does for you.  This is how many medical patients get hurt in the long run with such a cavalier attitude about drugs.

    I say better to take an Alternative Medicine approach to your problem to help your body heal and repair the Peyronie’s pathology naturally.

    Viagra Peyronie's Disease Connection

    Greater Viagra use and increase of Peyronie’s disease

    In a 2002 article in the International Journal of Impotence Research about possible causes of Peyronie’s disease, authored by Sikka and Hellstrom of Tulane University, these two medical researchers observed that with the increased use of Viagra, Peyronie’s disease also increased.

    In my work with the Peyronie’s Disease Institute, while corresponding with six to 10 men daily who have Peyronie’s disease concerning various aspects of their problem, I have also made this observation – that with greater use of Viagra, Peyronie’s diseases clearly increases.  The difference between Drs. Sikka and Hellstrom’s and my explanation why Peyronie’s disease is becoming more common as the use of Viagra – and other PDE5 drugs like Cialis and Levitra – increases around the world.

    Their explanation, quoting Drs. Sikka and Hellstrom’s report:

    “Peyronie’s disease usually affects 13% of males between the ages of 40 and 70, and the number of patients with such lesions have increased since the advent of oral sildenafil (Viagra, Pfizer) either because more men are becoming manifest and/or not hesitant anymore to come to clinics for such evaluations.”

    In other words, these two Tulane researchers say the only reason PD appears to be increasing is that more men are willing to talk about it, now that men are talking more about erectile dysfunction with the greater awareness brought about with the frequent TV and magazine ads about this problem and drug solution of it.

    While they offer the simple explanation that because men are becoming less hesitant to talk about their sexual problems, they assume more men are inclined to enter medical clinics asking for help – like asking for a prescription for Viagra, Cialis and Levitra.  That is certainly a possible explanation of perhaps some merit.   But that does not match my experience in talking with men who actually  have Peyronie’s disease.

    Peyronie’s and Viagra

    Men I talk to about starting Peyronie’s treatment still ask about how the mailing package will be labeled and if the return address will mention “Peyronie’s disease,” lest their letter carrier will learn they have PD.   I am asked if the credit card statement will mention that their therapy products are for treatment of PD, lest someone at the credit card company will learn they have PD.   I am asked by men how to explain the problem of Peyronie’s disease to a new girl friend so that she will not be scared away from a relationship with someone who has a disease of the penis.  I talk with men who do not want to talk at work about their PD lest someone overhears the conversation.  I learn from men that the worse thing about PD is not the pain associated with the scar development, but the loss of penile girth and length – something that most men would seem hesitant to tell the world about.

    I do not doubt for an instant that men are more relaxed and casual about admitting to a problem with erectile dysfunction, and more willing to ask for a Viagra prescription than they were a few years ago.  This is a more sexually open society – for good or for bad.  Yet, I doubt that men are just as willing to admit that they have Peyronie’s disease in which their penis is shockingly smaller than average or that can be so distorted as to be incapable of entry to engage sexual intercourse.

    Erectile dysfunction is one problem related to advancing age that perhaps has some dignity related to it and hope of easy drug solution, but Peyronie’s disease might not be seen in the same way since it is associated with permanent deformity and reduction of the size of the male organ.

    My opinion is that Drs. Sikka and Hellstrom are reluctant to discuss the possibility that these PDE5 drugs sporadically, irregularly and without warning cause severe injury to the tunica albuginea by extensive over-inflation of the corpora cavernosa of the penis.  The mechanism of this possible route of injury was discussed on 8-17-09 in the Peyronie’s Disease blog under the title, Peyronie’s Disease Treatment and Viagra, Cialis and Levitra, and again on 8-1-10 under the title Viagra, Cialis and Levitra Use with Peyronie’s Disease.

    These doctor’s hesitance to discuss or speculate that the increase of PD parallels the increase use of these drugs due to yet another drug side-effect of yet another group of drugs itself can be speculated upon.   Each man with PD must make up his own mind if this possibility makes sense to him, and if it is further reasonable to avoid the use of these drugs if he wishes to avoid further injury to his penis.     

    Cause of Peyronie’s Disease

    Trauma frequently seen as Peyronie’s cause

    While the cause of Peyronie’s disease remains open to speculation, some theories are more popular than others.  However it starts, it is important to remember that Peyronie’s disease is a disorder of the tunica albuginea.

    Among the several explanations for a possible Peyronie’s disease cause, trauma or direct injury to the penile shaft is almost always mentioned as either a primary cause or at least a significant secondary cause.  More specifically, the cause of Peyronie’s disease is universally explained as a wound that does not heal in the normal way, whether related to injury usually associated with sexual activity or a medical procedure. Even when other causes are mentioned it seems that injury will usually be associated in some way.

    Role of wound healing in Peyronies disease cause

    The penis contains two sponge-like, tube-shaped chambers (corpus cavernosae) with many tiny blood vessels that fill with blood during an erection.  Below the two corpora cavernosae is the corpora spongiosum through which runs the urethra or passage way to release urine from the bladder.  Each of the corpora cavernosa are enclosed in a thin and flexible sheath of elastic tissue called the tunica albuginea, which stretches slightly during an erection. Injury to the penis can cause inflammation and damage to the tunica albuginea.

    If an injury heals as it should then usually there are no long-term problems.  But if the healing of the injured tunica does not proceed as it should, it can lead to excess internal scar formation, known as Peyronie’s disease.  The area of the injured tunica albuginea is not as flexible as before injury.  With the area less flexible, when the penis attempts to become erect the region with the scar tissue doesn’t stretch, and the penis curves, bends, develops a dent or becomes distorted in some other way (bottle neck or hourglass deformity).

    The tunica albuginea has many layers, with very little blood circulation between them.  When an injury to the tunica albuginea occurs, the tissue fluids associated with the inflammatory process can remained trapped between these layers for many months. During this time the cells found in the inflammatory fluid can release chemicals that lead to increased formation of fibrous tissue (fibrosis) that causes reduced elasticity of that area, internal scar tissue and possibly calcification.  The combined effect of these tissue changes is the characteristic penile deformity associated with Peyronie’s disease.

    Inherited abnormality as cause of Peyronie’s disease

    There is some evidence of a genetic cause or predisposition to PD related to an inherited abnormality of human leukocyte antigen B27 (HLA-B27).  Peyronie’s disease is statistically more likely to occur in men whose immediate family members also have PD, or systemic lupus erythematosus (a connective tissue disorder).  PDI research shows that 37 percent of men with Peyronie’s disease also experience Dupuytren’s contracture, in which hard contracted develops on the palms of one or both hands.

    Other conditions as cause of Peyronie’s disease

    • Vitamin E deficiency has been associated with the Peyronie’s disease, primarily because early Peyronie’s disease research showed treatment with vitamin E demonstrated success in a significant number of cases.  Since that time less interest has been shown in using vitamin E as a Peyronie’s treatment.
    • Inderal and the PDE5 inhibitor class of drugs (Viagra, Cialis, Levitra) used to chemically stimulate development of an erection have been known to cause Peyronie’s disease.
    • Diabetes when severe or prolonged will precipitate damage to the blood vessels in any area of the body, including the penile shaft.  PDI research shows that 21 percent of men with PD also have diabetes.

    Regardless of the cause of Peyronie’s disease, it is important to start treatment as soon as possible to increase your ability to heal and repair the underlying injury to the tunica albuginea. Refer to the Peyronie’s Disease Institute website to learn how to start Peyronie’s disease treatment using Alternative Medicine.

    Drugs Can Cause Peyronie's Disease

    Prescriptions drugs that start Peyronie’s disease

    The cause of Peyronie’s disease remains unknown.  However, among the more commonly suspected causes are injuries as during intercourse, penile trauma as during a difficult catheterization procedure or surgery, genetic predisposition, or a problem of the immune system.

    Because medical Peyronie’s disease treatment is also poorly defined, with no standard drug receiving formal approval, one must wonder about the drugs that are currently being prescribed by medical doctors for their Peyronies patients.

    Several prescription medications list Peyronie’s disease among the potential side effects.  While no formal research exists that proves these medications cause Peyronie’s disease, presumptive evidence and frequent patient complaints of strong association with these drugs supports these as possible causes.

    1. 1. Beta Blockers – These are the most common medications in popular use that list Peyronie’s disease as a potential side effect.  Beta blockers is a class of drugs used for various indications, but particularly for the management of cardiac arrhythmias, protection of the heart after a myocardial infarction (heart attack), angina pectoris, atrial fibrillation, cardiac arrhythmia, congestive heart failure, glaucoma, migraine prevention, mitral valve prolapsed, and hypertension (high blood pressure). They tend to diminish the effects of epinephrine (adrenaline) and other stress hormones in the body, thus reducing cardiac demands.  If you have ever been treated for any of these conditions, and were treated with a beta blocker, this might explain a current case of Peyronie’s disease. Commonly prescribed beta blockers:

    Acebutolol                  Alrenolol                     Atenolol
    Betaxolol                 Bucindolol                     Carteolol
    Carvedilol                   Celiprolol                    Esmolol
    Labetalol                    Metoprolol                  Nadolol
    Nebivolol                    Penbutolol                  Pindolol
    Propranolol                Sotalol                        Timolol

    1. Interferon – This prescription medication is used to treat multiple sclerosis, leukemia, and hepatitis.  Its manufacturers list Peyronie’s disease as a possible side effect.
    2. Dilantin – This is a well established anti-seizure medicine, also reported by its manufacturers as a potential cause of Peyronie’s disease.
    3. PDE5 drug group (Viagra, Cialis, Levitra) – this is a group of inhibitor drugs that block an enzyme process of the smooth muscle cells lining the blood vessels supplying the corpus cavernosa of the penis.  As a result of this influence, these drugs act to increase blood flow in the penis in response to sexual stimulation.   The maker of each of these three drugs advises that men with Peyronie’s disease should consult with their doctors due to possible adverse effects on the penis.

    The bottom line concerning all these drugs is that every one of them has side-effects and related ways of complicating the problem of someone who is already sick.  Drugs should be used with great reserve and discretion, and avoided if at all possible.

    Once PD is present and a man learns that there is no known medical treatment available, he should consider using Alternative Medicine for Peyronie’s treatment options.  This is an option that the Peyronie’s Disease Institute has researched and developed since 2002, with considerable success.

    Viagra, Cialis and Levitra Use with Peyronie’s Disease

    Peyronie’s treatment using erection producing drugs

    The erectile dysfunction and soft erections associated with Peyronie’s disease are sometimes treated with Viagra, an erection causing drug made by the Pfizer Pharmaceutical Company.  The information about Viagra duplicated in this blog post is written by Pfizer about Viagra, in relation to Peyronie’s disease.   The basic information presented by Pfizer is essentially true for other erection producing drugs, like Cialis and Levitra.

    Here is the Viagra drug information from Pfizer, found their website.  I have removed a considerable amount of technical Viagra information that does not apply to Peyronie’s disease to make it easier to find what you need to know. Notice the section below that I have put in bold and underlined.

    PRECAUTIONS

    General

    The evaluation of erectile dysfunction should include a determination of potential underlying causes and the identification of appropriate treatment following a complete medical assessment.

    Before prescribing VIAGRA, it is important to note the following:

    The safety of VIAGRA is unknown in patients with bleeding disorders and patients with active peptic ulceration.

    VIAGRA should be used with caution in patients with anatomical deformation of the penis (such as angulation, cavernosal fibrosis or Peyronie’s disease), or in patients who have conditions which may predispose them to priapism (such as sickle cell anemia, multiple myeloma, or leukemia).

    The safety and efficacy of combinations of VIAGRA with other treatments for erectile

    dysfunction have not been studied. Therefore, the use of such combinations is not recommended.

    In humans, VIAGRA has no effect on bleeding time when taken alone or with aspirin. In vitro studies with human platelets indicate that sildenafil potentiates the antiaggregatory effect of sodium nitroprusside (a nitric oxide donor). The combination of heparin and VIAGRA had an additive effect on bleeding time in the anesthetized rabbit, but this interaction has not been studied in humans.

    Use of any drug to assist erections in Peyronie’s disease

    It is my opinion that any man who is undergoing Peyronie’s disease treatment is taking a huge risk to use any of these erection producing drugs because it has been my observation and experience in talking to hundreds of men about their Peyronies problem, that these drugs can injure the penis and actually start Peyronie’s disease, make it worse, or possibly delay or interfere with your effort to try to heal your Peyronie’s plaque.   This happens because of the damage done by the surprisingly strong and uncontrollable erections these drugs can create.

    With the use of these drugs it is possible that the forced erections they cause can place great internal stress within the penis that can injure the delicate tunica albuginea.  The erections created by these drugs can be indeed super-erections, greater than what a man normally experiences.

    I have had a number of men tell me they are convinced their Peyronie’s disease started after using Viagra, Cialis, etc.   I am confident that at a later time we will start to hear reports about more side-effects of these medications.  This should not be so difficult to believe when you can read for yourself that the drug manufacturer is already warning men in particular with Peyronie’s disease to be cautious about its use.

    Peyronie’s disease aggravated easily

    Super-charging an erection is not the way the body was designed to be used.

    What if you could take a drug that would enable you to lift a ton of weight above your head and keep it there for an hour?  Nice trick, very impressive, but your body is not built to take that kind of pressure to the muscles, ligaments, joints, bones and blood vessels.  A trick like that would cause great damage to internal organs, your spine, blood vessels, all major joints, etc.  Simply put, “It just ain’t natural.”  Same with these erection drugs like Levitra and Viagra.  The increased pressure created by these medications can be very damaging to the delicate tunica albuginea, and can result in or worsen a case of PD.

    What would happen to your car tires if you happened to over-inflate them with 100 pounds of air pressure, even though they were built to take just 40 pounds of pressure?  You would be running the risk of damage to the internal structure of tire, wouldn’t you?  Of course.  The same thing can happen if the penis is over-inflated and then given a “rough ride.”  This is where the problems start, and this is what I want to bring to your attention.

    Viagra, Cialis and Levitra are not a Peyronie’s treatment

    It is very likely that the MDs who prescribe these medications to men with Peyronie’s disease will not agree with this thinking.  MDs tend to favor a chemical “fix” to most problems, so you would tend to expect a natural and automatic prejudice from an MD to use drugs to solve most problems.

    If you have taken Cialis or any other erection producing drug because it was prescribed for you, and you mention this information to your MD, what do you suppose he or she will say?  Well, the first thing you must consider is that this information indicates that your doctor prescribed something for you that was not safe or appropriate.  The natural reaction would be for your doctor to immediately defend her decision.  That makes sense.  It is not my intention to make trouble for your doctor, she was only doing what she thought was best for you.  It is my intention for you to independently think about these things and see if they make sense to you, the owner of the penis that could become injured.  Do more research on your own, then talk to your doctor.  This way you are armed with both sides of the story.

    It is my further intention to prevent you from injuring yourself further with these erection producing drugs.

    A penis that is predisposed to Peyronies in the first place cannot tolerate the kind of stress that these erections drugs create.  It is just like someone with asthma cannot tolerate dust, odors or smoke that does not bother other people.  If you already have Peyronies you should do everything you can to avoid any kind of stress to this tissue, including avoidance of erection producing drugs.

    I talk to a lot of men who are given a prescription for Viagra, etc. to help their sexual difficulty, and they instinctively know that this treatment does not make sense to them.  Yet, they are tempted to use the drug because of the promise of improved sexual performance; besides, they are also tempted because they feel, “Heck, my doctor would not do anything to hurt me, maybe it is OK to do.”  I would agree, your doctor would not want to hurt you intentionally.  Yet, we all know that tens of thousands of people are hurt each year by drugs that are given with good intentions and bad consequences.

    In addition, I have talked to many men who have reported to me that they used these erections drugs many times, maybe for several months, with absolutely no problem.  The erections were “normal” and controllable, and everything was fine, and the sex was great.  Then, one night, one time, they took that same drug in the same way, and they got an erection that was unbelievably hard and huge, and they thought they were going to explode.  It scared the devil out of both partners.  A few days or weeks later – a curved penis and Peyronie’s disease developed.

    If you attempt to think independently and logically about what might happen to your Peyronie’s disease when these drugs are used, you should have no trouble understanding how this could work against you.  If your doctor can convince you that they are perfectly safe, then you should do what your doctor says to do. Just remember, who that penis is attached to if a tragedy happens.  Your doctor will shrug his shoulders; you will have a worse case of PD.

    My opinion is that the use of Viagra and similar erection drugs could easily be worsening the very problem you are attempting to heal.   The use of these drugs represents a calculated risk that you are taking, and you should be aware of it.

    Please write a comment or question about this article if you want to know more about Peyronie’s disease treatment with Viagra, Levitra or Cialis.

    Peyronies and Viagra

    Peyronies and Viagra are connected

    Questions about Peyronie’s disease and Viagra are common.   Viagra, one of the PDE5 inhibitor drugs, is wildly popular and widely used not only among men who have erectile dysfunction (ED, impotence), but healthy men who merely use it to have longer lasting and more repetitive sexual intercourse.

    While I hate to spoil the fun, over the years I have had a disturbing number of men tell me that they now have Peyronies – and Viagra was the cause of it.  They report the erection that occurred after using Viagra was a super-erection and caused greater than normal internal pressure and pain.  Shortly after having such an episode they report having Peyronie’s disease; they reason that Viagra use is the only possible cause, because no trauma occurred.

    It makes sense that any of the PDE5 inhibitor drugs (Cialis and Levitra are the others) increase pressure that is sometimes greater than normal with the tunica albuginea. In addition, these drugs create such hard and long-lasting erections because they induce an artificial condition within the penis.

    If it were possible to take a drug that would allow you to lift a truck above your head and keep it there for an hour, should you do it?  That would be an interesting, and very impressive to the ladies, but is that reason enough to subject your body to the potential risk that would be involved?   The fact is that the body is not built to be used that way.  Lifting a great amount of weight causes internal pressure on tissue and organs that were not meant to bear that kind of weight.  Great injury would occur to internal organs, your spine, knees, hips, shoulders, blood vessels, and so on.  The same relationship exists between Peyronies and Viagra, and the rest of these products.

    All of this is so unfortunate because there are far safer methods for Peyronie’s disease treatment.

    Even though it sounds like a teenagers dream come true, the penis is not designed or intended to sustain such great internal pressures that are created by these drugs, nor is the penis built to be used in hour after hour of intercourse.  Just because you can, doesn’t mean you should.  That kind of activity can be abusive to the delicate tunica albuginea and could be the connection between Peyronies and Viagra or any other PDE5 inhibitor drug.

    Several months ago a man told me he injured his penis while using Viagra.  He took some Viagra for the first time to the delight of his wife, and him.  After rousing intercourse, both fell asleep except his penis stayed erect.  He enjoyed the enormous erection and at first he thought it was great.  While asleep with this huge erection he rolled over and jammed his penis into the mattress.  In great pain, he heard and felt the tissue of the penis “pop.”  Two months later he was diagnosed with Peyronie’s disease.

    Weekly I am told or I read that MDs write orders for their patients with Peyronies and Viagra is the most commonly prescribed drug.   The MD will explain that the Viagra will increase the blood flow to the penis and this is beneficial to Peyronie’s disease.  I think this is nonsense.

    While there is an increased amount of blood within the penis during an erection that causes the greater size of the organ, it is perhaps only 2-3 tablespoons more blood than is normally present.  But here is the most important point that explains why this idea is so silly:  The extra blood, and even the normal amount of blood that is inside the penis during an erection, is TRAPPED there.  It is not freely flowing, or moving in and out as you would like to happen, to actually increase circulation.  During an erection, there is less true circulation of blood – that is why the penis gets darker, because there is less oxygen present – and so there is no therapeutic purpose in creating super erections with Viagra because that is not the way to get better circulation.

    A man would know he actually is suffering from poor circulation in his penis, just as he would know he has poor circulation in any other part of his body – like his feet or hands.  When the feet or hands have poor circulation they become cold, painful and pale.  If your penis is not cold, painful and pale, then reduced circulation is probably not your problem.  And enduring prolonged erections from a PDE5 inhibitor will not help your Peyronie’s disease, and could make it worse.

    If you want to increase circulation to the penis, you can do it as you would to your feet or hands.  You would apply heat to the area as with a hot water bottle, or cover it with a blanket.  You can even rub it!  It is as simple as that.

    The increased occurrence of Peyronies and the increased use of Viagra is not a coincidence.  There is a reason more and more men are getting Peyronie’s disease at the same time that more and more men are using Viagra and the other PDE5 inhibitors.  Now you know about Peyronies and Viagra.

    Peyronie’s Treatment and Cialis

    Peyronie’s and Cialis (Tadalafil) and PDE5 inhibitors

    Peyronie’s and Cialis are both on the rise – no pun intended, and there is a reason for that.

    Cialis it is not a Peyronie’s treatment; Cialis is used to treat erectile dysfunction (impotence).   Some MDs use Cialis in Peyronies treatment because they think it will help the patient achieve a stronger erection  since Peyronie’s disease and impotence or erectile dysfunction often occur together.    But    This practice is is coming under close scrutiny because Viagra, Cialis and Levitra (all the PDE5 inhibitors) can make Peyronies worse if they cause a very extreme erection that the body is not built to handle.  This can cause damage to delicate tissue and more Peyronie’s plaque formation.

    Peyronie’s and Cialis Usage

    Every man should know each package of Cialis contains information warning that men with Peyronie’s disease should use Cialis with great caution because of possible side effects that include damage to the penile tissue that can actually cause Peyronie’s disease if you do not already have it.

    MDs write orders for their patients with Peyronies and Cialis is a commonly prescribed drug.   The MD will explain that the Cialis will increase the blood flow to the penis and this makes it beneficial to Peyronie’s disease.  I think this is nonsense.

    An erection is created when blood is TRAPPED inside the penis, causing the spongy tissue to fill up and expand with about 2-3 tablespoons more blood than is normally in the penis.  This additional 2-3 tablespoons of blood become TRAPPED inside the penis, just like when you blow up a balloon and tie a knot at the end of the balloon.  Sure there is more air inside the balloon, but it does not circulate freely – it is stagnant air. And the additional blood also does not circulate freely in the penis.  That is why the penis is darker when it is erect – the blood does not have much oxygen in it, making the tissue darker.  This just goes to show how little many MDs think about what they are doing when they write a prescription.

    Cialis is a popular erectile dysfunction drug, but it does not make sense to use it for treatment of Peyronie’s disease. When a man goes to his doctor for his Peyronie’s and Cialis is prescribed, he should understand the reason for the prescription does not make sense.

    Cialis and Peyronie’s Connection

    While I hate to spoil the fun for those whose sex life is enhanced by Cialis, but over the years I have had a disturbing number of men inform me they now have Peyronies and Cialis use was the cause.  Any of the PDE5 inhibitor drugs (Viagra and Levitra are others) can increase pressure within the penis that  can be greater than normal.  Injury to the tissue can lead to Peyronie’s disease.

    If it were possible to take a drug that would allow you to lift a truck above your head and keep it there for an hour, should you do it?  That would be an interesting, and very impressive to the ladies, but is that reason enough to subject your body to the potential risk that would be involved?   The fact is that the body is not built to be used that way.  Lifting a great amount of weight causes internal pressure on tissue and organs that were not meant to bear that kind of weight.  Great injury would occur to internal organs, your spine, knees, hips, shoulders, blood vessels, and so on.  The same relationship exists between Peyronies and Cialis, and the rest of these PDE5 inhibitors.

    All of this is so unfortunate because there are far safer methods for Peyronie’s disease treatment.

    The increased occurrence of Peyronies and Cialis use also increasing is not a coincidence.  There is a reason that more and more men are getting Peyronie’s disease at the same time that more and more men are using Cialis and the other PDE5 inhibitors.

    Peyronie's disease treatment and Viagra, Cialis and Levitra

    Questions about Viagra, Cialis and Levitra, and Peyronie’s disease

    Boy, do I get questions about Viagra, Cialis and Levitra and Peyronie’s disease!  Most of these questions come from men who are taking these drugs on the advice of their MDs who using it as part of their Peyronies treatment efforts.

    These drugs are wildly popular, not only among men who have erectile difficulty ( Peyronie’s disease  impotence) but also healthy men who merely use them to have longer lasting and more repetitive sexual intercourse.

    Sounds like a good thing, doesn’t it?

    While I hate to spoil the fun, but over the years I have had a disturbing number of men tell me they know their PD started after using Viagra, Cialis, etc.   The erections created by these drugs are indeed super-erections and get to be that way because of the greater than normal internal pressure that is created within the tunica albuginea.  This is powerful stuff that can really cause problems in this delicate area of the male body.

    These drugs create such hard and long-lasting erections because they induce an abnormal state in the penis. What if you could take a drug that would enable you to lift a ton of weight above your head and keep it there for an hour?  Nice trick, very impressive, but your body is not built to take that kind of pressure.  It would cause great damage to internal organs, your spine, your blood vessels, all major joints, etc.  Simply put, “It just ain’t natural.”  Same with Peyronie’s treatment with Viagra, and the rest of these products.

    As much as it might sound like a dream come true, the penis is not built to sustain increased internal pressures that are created by these drugs, and the penis is not built to have hour after hour of intercourse.  That kind of activity can be abusive to the delicate tunica.  Just because you can, doesn’t mean you should.

    I have an interesting story from a man who called me a few months back and explained that he injured his penis in a most unusual way.  He and his wife had used Viagra for the first time to their mutual delight.  Both of them went to sleep, except his penis continued to stay erect.  It was a monster of an erection and at first he thought it was great.  During the night, while asleep with a huge erection, he rolled over in bed and jammed his penis into the mattress.  He felt a great pain and felt the tissue “pop.”  Basically he tried to pole vault on his erection and he found his penis could not sustain that force.  About two months later he developed PD.  Can you imagine what would happen if you already have Peyronies disease and had something like that happened?  You would go from bad to worse.  This man did.

    I know many men with PD have their MDs write prescriptions for these erections drugs.  I am sympathetic why men do these things.  They figure if it was not good for them the MD would now do it.  What they forget is that most MDs do not understand or care about PD, and are more interested in getting the fee for the office visit, than doing what is the smart thing to do.  MDs also perform surgery for PD that makes the problem worse, knowing there is a high rate of poor surgical results from this kind of surgery.  Just because you can get a prescription for it doesn’t make it any safer or any less stupid in the long run.

    Use your head and stay away from these forced erections.

    One last metaphor.  Your car tires are designed to hold 40 pounds of air pressure.  What would happen if you decided to increase the pressure to 80 pounds, just for “the fun of it?”  Well, first of all, we would all understand the tire would be much more likely to blow up and pull away from the rim because it was not built to be used that way.  It would be damaged by applying more pressure to it than it was built to take.  Enough said.

    Peyronie’s Disease Institute has access to some really great Oriental herbal erection enhancing – not forcing – products.  These will easily and gently boost your erectile ability but not in such a forceful way that you will get hurt.  They surely do work, but with no side effects, they last a good 8-12 hours, and they are a whole lot less expensive than your prescription drugs.  Let me know if you are interested and I will give you some information about these wonderful and safe products.

    Peyronie’s Disease Plaque, Viagra, Cialis, Levitra, and Blood Supply

    Different way to look at Peyronie’s disease and blood supply

    Peyronie’s disease is all about the Peyronies plaque, because the Peyronie’s plaque causes all the problems we normally associate with this condition.  To back this idea up, and to show you are doing something that is potentially dangerous to your Peyronie’s disease by using erection enhancing drugs, let’s review some interesting research that took place about 15 years ago.

    First, some background.  According to two Peyronies disease researchers, Drs. J. A. Lopez and J. P. Jarrow, from the Department of Urology, Bowman Gray School of Medicine of Wake Forest University, Winston-Salem, North Carolina, most of the erectile dysfunction that is associated with Peyronies disease is probably not due to reduced blood supply coming into the penis.  Hence, taking Viagra, Cialis, Levitra, or any erection producing drugs, is often not effective and when it is it could be dangerous when someone with PD takes any erection producing drug.

    Let’s get through the technical material first and then I will put it all together as it relates to using these drugs because you have Peyronies.

    In the study done by Lopez and Jarrow, they did a penile vascular (blood flow) evaluation; they tested the penis arteries (to determine blood flow coming into the penis), and they tested the penis veins (to determine the blood flow leaving the penis).

    They tested 95 consecutive men who came to them for evaluation or treatment of Peyronie’s disease; of these 95 men, 19 were potent (able to become erect) and 76 were impotent (not able to become erect).  They also did the very same kind of penile vascular (blood flow) evaluation on 100 consecutive impotent men who did not have Peyronie’s disease so they could compare the condition of their blood vessels as it relates to erections and erectile dysfunction.

    Potent men with Peyronie’s disease

    After testing the 19 potent men who had Peyronie’s disease, they found only one (5%) of the 19 potent patients had abnormal arterial blood flow coming into the penis, and none (95%) had evidence of abnormal venous blood supply leaving the penis.

    Impotent men with Peyronie’s disease

    After testing the 76 impotent men who had Peyronie’s disease, they found that 27 men (36%) had abnormal arterial blood flow coming into the penis, and 44 men (59%) had evidence of abnormal venous blood supply leaving the penis.

    Potent and Impotent men who did not have Peyronie’s disease

    There was no significant difference in historical risk factors for impotence between the impotent men with or without Peyronie’s disease and the control population of impotent patients.

    After testing the 100 men who did not have Peyronie’s disease they found they had about the same percent of abnormal arterial blood flow coming into the penis.  However, they found these same men had significantly less (16%) abnormal venous blood supply leaving the penis.

    So the big difference was that the impotent men (59%) with Peyronie’s disease had a whole lot more abnormal venous blood supply leaving the penis, than the impotent men (16%) who did not have Peyronie’s disease.

    This means that although men with Peyronie’s disease may suffer some impotence due to artery blood flow problems, the research proves that the primary and overwhelming cause of impotence in men with Peyronie’s disease is abnormal venous blood supply leaving the penis.

    So you ask, “What could be wrong with my venous blood flow leaving my penis?”  Answer:  your Peyronie’s plaque.

    Peyronie’s plaque causes impotency

    It is the Peyronie’s plaque that causes the veins of the penis to not close properly. Click here to understand a bit about Peyronie’s disease and erection.

    There are special valves within the veins of the penis that close off at special times, to trap the blood inside the penis – to create an erection.  If the veins do not trap the blood, no erection.  The presence of the plaque or scar material is the problem that causes the valves of the veins to not trap blood, hence a poor or absent erection.  Yes, there are surely many emotional reasons a man with Peyronies will develop impotency, but this vein problem is by far the primary physical reason for this erection problem that we all are interested in.

    Imagine that you want to close a door to trap warm or cold air inside a room.  You try to close the door, but you cannot because there is something causing the door to not close all the way – perhaps the door is warped, or maybe there is something lying across the doorway like a doorstop and the door will not seal the room shut.  If the door cannot be closed fully, it will be difficult or impossible to close the door, and you cannot trap the air in that room. It is the same in Peyronie’s disease. If the valves of the veins cannot be closed fully, it will be difficult or impossible to close them, and you cannot trap the blood to create the erection.

    The presence of one or more Peyronie’s disease plaques or scars can and will cause physical interference with the normal closing of the valves inside the penis veins and one or more areas of the penis stay soft, preventing intercourse.  It is as simple as that.

    So your medical doctor, hearing that you are having a problem with impotence along with your Peyronie’s disease says to you, “Do not fear.  I have my magic prescription pad here.  I will happily write a prescription for  Viagra, Cialis, or Levitra and you will get an erection that will amaze and delight the woman you love, and amaze all your family, friends and neighbors.  Please pay the nurse at the front desk as you leave.”

    Elsewhere I will write more about the potential dangers of erection producing drugs like Viagra, Cialis, and Levitra in relation specifically to Peyronies.  For this discussion it is sufficient to state that Viagra, Cialis, and Levitra only bring more blood into the penis.  The do not and cannot help you to trap it there to create an erection.  This is why they may or may not work for you, and in fact, could potentially make your Peyronie’s disease worse.

    For more information about the safe and effective treatment of Peyronie’s disease with Alternative Medicine, go to the Peyronie’s Disease Institute website.