Why is acetyl-L-carnitine not mentioned on your website?

I'm wondering why is Acetyl-L-carnitine not mentioned on your website for treatment of Peyronie's disease?  I have read some really strong research findings about acetyl-L-carnitine and am eager to try it out.  

Thanks, Bruce

Greetings Bruce, 

You are incorrect, Bruce, acetyl-L-carnitine is mentioned often. We have highly recommend the use of acetyl-L-carnitine since 2002. 

Please go to this large page on the PDI website that explains what you need to know about this excellent PD therapy,  Acetyl-L-Carnitine and Peyronie's Treatment.   For a bit more go to the PDI store to read Acetyl-L-Carnitine and Treatment of Peyronie's Disease where I refer to this therapy as an All-Star product. 

To learn how to use this therapy product, and others, for ideas and suggestions to put it all together, click Create a Peyronie’s Treatment Plan    TRH

How to Change Peyronie’s Treatment If Not Effective

In 2002 I started working exclusively with men who have Peyronie’s disease.  Since that time I have noticed a common pattern with men about 6-8 weeks after the start of their treatment with Alternative Medicine.  This pattern occurs no matter the size of the PD treatment plan a man uses, or even with some personalized modification of a standard PDI plan based on personal needs.

It seems that after seeing some initial changes in the size, shape, density or surface quality of their scars at about 6-8 weeks of treatment, improvement and progress will often level off or plateau.  It seems that most men assume that all recovery and progress remains on a level and constant course, like putting your foot on the accelerator of a car.  When they begin to notice their improvement has slowed down or stopped, they are stumped about what to do next.  They will not know what to do with their current plan to improve it or modify it to assure continuation of those early positive changes.

Time and again I have seen this pattern:  Start care, make progress, slow down or stoppage of progress.  What must be done is some modification of the initial treatment (usually increase of treatment in some way) to again stimulate the healing capability of the tissue.  This can be expressed as: Increase care by increasing current therapy or adding new therapy, re-stimulate immune response, make additional progress, monitor for next slow down.  What happens after the next slow down or stoppage can be expressed in the same way:  Increase care again in a same or different way, re-stimulate immune response, monitor for next slow down, and so on.

This process of exactly how to slowly modify Peyronie’s treatment to increase activity of the immune response against the PD scar is where the day-today challenge is found – and it is not easy.

Peyronie’s treatment plateau of progress

It is common for a man who experiences his first plateau of progress to think only in terms of adding more therapies to his treatment lineup to re-energize his recovery.   If he has gotten good results from a medium size PD plan, he will assume he must add one or more therapies that are not part of his current plan – like PABA, or the Genesen pointers, or acetyl-L-carnitine, or Unique-E vitamin E oil as an external application or the gentle manual penis stretching technique, etc.  However, this is usually not necessary and not the best course of action.

From my experience, to help you get off your plateau and begin progressing again toward additional recovery it is best to work within the same group of therapies that was good enough to create your initial improvement.  This is usually accomplished by slowly and carefully increasing the dosage of one of those therapy items a little at a time.  If you develop any unusual problem/symptom while increasing your dosage, simply stop taking the product for 48 hours, and restart from the next lower dose.  When you reach the highest dose where you had no problem or symptom, stay at that dosage level for a few weeks.  After 2-3 weeks without problems, then slowly increase the dosage until you are at the desired level.  You will know you are taking the correct effective dose when you begin to see improvement in your scar size, shape, density or surface texture.

Modify slowly and deliberately

If no improvement or change occurs in the features of your scar after being on the increased dosage for about 14 days, then increase the dosage again.  Repeat this process until you begin to note improvement in your scar size, shape, density or surface texture.

Only after you have attempted to increase all therapies singly, and have attempted to increase several therapies together as a group, and all have shown to be unsuccessful should you then consider expanding the number of different therapies you use – like adding in PABA, or the Genesen pointers, or acetyl-L-carnitine, or Unique-E oil as an external application or the gentle manual penis stretching technique, etc. to your Peyronie’s treatment plan.

Peyronie’s Disease Vitamin Therapy

Peyronie’s disease vitamin E treatment and other nutrients

There are many important nutrients – vitamin, mineral and amino acids – that should be used to improve and support the ability of the body to heal and repair the Peyronie’s plaque and help reverse the curved penis it causes.  However, since starting this work in 2002, I have never heard of a medical doctor prescribe any supplement other than vitamin E.  I think this says a lot about what MDs know about Peyronie’s disease vitamin therapy; their knowledge is limited, focused only to the obvious, and tends to not go beyond what everyone else is prescribing.

Vitamin E and Peyronie’s disease

The standard Peyronie’s disease vitamin E recommendation of the medical profession is to “get some vitamin E, and take no more than 400 IU a day.”  Occasionally the dosage will be doubled to 800 IU daily of vitamin E by some doctors who think outside the box a bit.  This is important to remember because vitamin E is essentially the only non-drug Peyronie’s disease vitamin treatment that is suggested to a man with Peyronie’s disease.

Vitamin E is available in both a synthetic form and a naturally occurring organic form.  Which form you decide to use ultimately determines how much can be taken safely.  There are eight different members of the vitamin E family.  Four are known as tocopherols and the other four are tocotrienols.  The most widely found vitamin E member is gamma tocopherol, which assists the elimination of nitrogen free radicals, as well as being an effective anti-inflammatory agent.  Tocotrienols are primarily found in the skin and subdermis where they protect against UV and free radical damage. Tocopherols are found in the major organs.  A balanced diet – very difficult to achieve these days – contains all eight members of the vitamin E family.

Because of costs and chemical stability,  and because early research proposed it was the only member of the family to have biologic benefit to man, most vitamin E supplements contain only alpha tocopherol.  This means most men on Peyronie’s disease vitamin therapy as prescribed by their medical doctor will receive only one of the eight members of the vitamin E family.  Since the early days of vitamin E research (not so long ago in the 1950s) it has been proven repeatedly that the complete vitamin E family, stressing gamma tocopherol and tocotrienols in their natural and unesterified form, accelerate wound healing and minimize scar formation.   For this reason I am most insistent that men using Peyronie’s disease vitamin E treatment use a high quality vitamin E product that is heavily slanted toward gamma tocopherol and all the tocotrienols, like Yasoo Health’s Factor 400/400.

If you are concerned about vitamin E safety issues, please read Peyronie’s Disease Treatment and Vitamin E that answers all dosage and safety questions.

The body is like a house

In order to build a solid house and have it operate well, it is necessary to have a wide variety of components available during the construction phase and during the long maintenance phase when the house begins to need help in the form of repairs.

During the construction phase, many problems would develop if all the builder had to work with were roof shingles, or just windows, or just doors.  A wide variety of components are needed to make a good house – lumber of various widths, thicknesses and lengths, concrete, plywood, along with nails, dry wall, electric wire, and so many other hundreds of different things.

During the maintenance phase, many replacements and repair items are needed.  If the home owner only had nails, or furnace filters, or pale yellow paint to work with, it would not help a bit if the problem was a leaky roof, a squeaky door, or a leaky faucet.

It makes sense that a wide variety of replacement and repair parts are needed for all the parts of a house.  It also makes sense that a Peyronie’s disease vitamin therapy program has to also be broad and diverse.   How does it make sense that all the problems of Peyronie’s disease are solved with just vitamin E?

Peyronie’s disease vitamin, mineral, and amino acid treatment

Peyronie’s Disease Institute uses a variety of different nutrients to satisfy the many needs of the body to have all the needed supplies to heal and repair the scar tissue in the best way possible.

Look at the list of different products that are suggested for use in the large Peyronie’s treatment plan.  The list is long because the process is complicated.   Of course, even the large plan does not contain all the nutrients that could be recommended to heal and repair the Peyronie’s plaque; PABA, acetyl-L-carnitine, quercetin, bromelain and herbs to stimulate the process are just some of the additional therapies that can be used.

Your house is large and complicated, but it is nothing compared to the body. When the body develops Peyronie’s disease it just does not make sense to attempt to fix it with vitamin E only.  That would be like trying to fix a broken window with a screw driver.   The screw driver might be a useful to remove some glass from the window frame, but other tools – and glass – will be needed for the repair to be done correctly.

For more information about successful Peyronie’s disease treatment.