Drugs Can Cause Peyronie's Disease

Prescriptions drugs that start Peyronie’s disease

The cause of Peyronie’s disease remains unknown.  However, among the more commonly suspected causes are injuries as during intercourse, penile trauma as during a difficult catheterization procedure or surgery, genetic predisposition, or a problem of the immune system.

Because medical Peyronie’s disease treatment is also poorly defined, with no standard drug receiving formal approval, one must wonder about the drugs that are currently being prescribed by medical doctors for their Peyronies patients.

Several prescription medications list Peyronie’s disease among the potential side effects.  While no formal research exists that proves these medications cause Peyronie’s disease, presumptive evidence and frequent patient complaints of strong association with these drugs supports these as possible causes.

  1. 1. Beta Blockers – These are the most common medications in popular use that list Peyronie’s disease as a potential side effect.  Beta blockers is a class of drugs used for various indications, but particularly for the management of cardiac arrhythmias, protection of the heart after a myocardial infarction (heart attack), angina pectoris, atrial fibrillation, cardiac arrhythmia, congestive heart failure, glaucoma, migraine prevention, mitral valve prolapsed, and hypertension (high blood pressure). They tend to diminish the effects of epinephrine (adrenaline) and other stress hormones in the body, thus reducing cardiac demands.  If you have ever been treated for any of these conditions, and were treated with a beta blocker, this might explain a current case of Peyronie’s disease. Commonly prescribed beta blockers:

Acebutolol                  Alrenolol                     Atenolol
Betaxolol                 Bucindolol                     Carteolol
Carvedilol                   Celiprolol                    Esmolol
Labetalol                    Metoprolol                  Nadolol
Nebivolol                    Penbutolol                  Pindolol
Propranolol                Sotalol                        Timolol

  1. Interferon – This prescription medication is used to treat multiple sclerosis, leukemia, and hepatitis.  Its manufacturers list Peyronie’s disease as a possible side effect.
  2. Dilantin – This is a well established anti-seizure medicine, also reported by its manufacturers as a potential cause of Peyronie’s disease.
  3. PDE5 drug group (Viagra, Cialis, Levitra) – this is a group of inhibitor drugs that block an enzyme process of the smooth muscle cells lining the blood vessels supplying the corpus cavernosa of the penis.  As a result of this influence, these drugs act to increase blood flow in the penis in response to sexual stimulation.   The maker of each of these three drugs advises that men with Peyronie’s disease should consult with their doctors due to possible adverse effects on the penis.

The bottom line concerning all these drugs is that every one of them has side-effects and related ways of complicating the problem of someone who is already sick.  Drugs should be used with great reserve and discretion, and avoided if at all possible.

Once PD is present and a man learns that there is no known medical treatment available, he should consider using Alternative Medicine for Peyronie’s treatment options.  This is an option that the Peyronie’s Disease Institute has researched and developed since 2002, with considerable success.

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