Question about Kegel exercises

Dr Herazy, in practicing the Kegel technique,is it necessary to hold your breath and tighten your stomach muscles during contraction?


I assume you are referring to doing the Kegel exercises in treatment of PD, as described in video,  “Massage and Exercise for Peyronie’s Disease.”   It is not necessary to do either of these, although it is difficult not to do so.  What is essential is that you do not focus or center your attention to the abdominal muscles since these are not the muscles that you are interested in strengthening while trying to treat your PD.  You should be focused on contracting the deep pelvic muscles known as the pubococcygeus, or PC muscles.   If you are not contracting these important PC muscles then you are wasting your time and effort.    All of this is explained in the CD.  Perhaps it would be a good idea to watch it again.   TRH

How do I develop synergy to treat my Peyronies disease?

Been searching your site, have ordered Neprinol, but have not found the alternative product suggested for the synergy ‘maybe’ needed — besides Vitamin E, which I take.


Please read this page from the PDI website, “Synergy and Treatment of Peyronie’s Disease.”

In this discussion you will learn that synergy results from the combined use of several different therapies, but not any particular therapies.   For successful Peyronie’s disease treatment the more therapy and wider variety of therapy products that are used, the deeper and more effective your synergy will be – the more the merrier.

Synergy is a natural reaction when groups of similar things are combined.   Let’s take for example people.    If we combine a group of people who are slightly bad, when they get together they will tend to do things and behave in a way that is generally more bad than they would if they were not together.   In a similar way,  if we combine a group of people who are good, when they get together they will tend to do things and behave in a way that is generally better than they would if they were not together.  I suppose you can say that by combining similar things the natural tendency of those things is intensified. This is synergy. There is no limit to the number of things you can add for synergy to happen, and everything seems to be affected by it so you can use any Peyronie treatment you want to cause it to help you.

In the Alternative Medicine treatment of Peyronie’s disease we  use different therapies that have been shown to be slightly effective as a Peyronie’s therapy.  But when you combine them – the more the better – you get an increase of this ability to reverse  the Peyronies problem.

Further, since no one can tell which of the Peyronies therapies you need most and which you are lowest in, we approach treatment from a broad base that you supply all of those that could be helpful so that you are not missing any and this will also strengthen the effect of synergy on your problem.  Let me know if you have any more questions about the Alternative Medicine treatment of Peyronies disease. TRH


Is it best to take Neprinol on an empty stomach?

Hi Dr. Is it best to take neprinol on an empty stomach ?



Yes, it is best to take Neprinol at least 90 minutes before or ninety minutes after you eat.

If you are only taking Neprinol as a Peyronies treatment you are likely making a mistake.   Neprinol works best when taken as the primary component of a larger aggressive treatment plan.

You are also making a mistake by buying your Neprinol from people who do not know about Peyronie’s disease and cannot guide you and give you advice for care.  When you purchase Neprinol form PDI you will be given a great amount of information that will tell you how to use this product – and all the other products you will need to take  –  correctly.   Our prices cannot be beat and out PD help is second to none.   TRH

Peyronie's treatmet using compression

Greetings Again and Happy New Year, Dr. Herazy …

Thank you once again for your helpful reply.

While discussing further options to mitigate my Peyronie’s with my urologist today, he shared that a colleague had successfully treated a Peyronie’s patient with PRP (“Platelet-Rich Plasma”) injections …. which you may readily recognize as the treatment administered successfully to Tiger Woods about a year ago for a knee injury. My urologist, though, hastened to advise me that this procedure is clearly experimental, non-FDA approved, and not covered by health insurance. Anyway, I was wondering if you’ve heard of this procedure as a Peyronie’s treatment; and, if so, what are your thoughts, concerns, cautionary advisories, etc.?

Also, speaking of non-conventional Peyronie’s treatment regimens, I read something recently about the use of “compression”, whereby the penis is rubber-banded in the area of curvature with the intent of breaking up the plaque. I believe this procedure had been tried with some success in India or elsewhere in SE Asia. Have you heard of such a procedure?  Is there any basis for the possibility of plaque being mitigated by a compression technique …. be it rubber-banding or other like technique?

Thank you for weighing in on the above.



Greetings Phil,

Give me a little time to investigate PRP and I will get back to you.

Compression of the penis, because it is such a soft mass of tissue, would work like a tourniquet to greatly reduce blood circulation to the point that significant tissue injury could occur – leading to more Peyronie’s disease.   In fact, many men who have used a device known as a “cock ring,” that is designed to block blood flow in the penis, have reported that they developed PD afterward.  This is a dangerous idea when applied to the penis that i would advise against.  TRH

Have you any knowledge about serrapeptase or nattokinase for Peyronie's treatment?

Hi, I just ordered your massage CD.

Have you any knowledge on the product serrapeptase or nattokinase?

They are in a category of systemic enzymes which are fibrolytic — fibrolytic enzymes break down fibrin and reduce or prevent scarring. Examples of these are serrapeptase and nattokinase. So, more precisely, could a fibrolytic enzyme like serrapeptase possibly reduce the fibrosis in the penis?

Best to you,



Greetings Michael,

Certainly.  Since 2002 PDI has advocated the use of the fibrinolytic enzymes, nattokinase and serrapeptase to treat Peyronies disease.  You may learn more about them here Enzymes (Neprinol, Nattokinase and Fibrozym) for Peyronie’s Treatment.   TRH


I need real complete information on what Peyronies treatment to use

I have a minor nodule on the forward 1/3rd of my penile shaft. It causes a twist up and mostly to the left when erect. I have been taking two 400 vitamin E caps a day and essential oil application once a day.  My Dr. suggested using the vacuum cup but I’m not convinced that this product is affecting the source of the problem. After reading some of the blogs here, I’m seeing that there’s more meds or supplements involved that may or may not have real effects on my condition.  I need real, complete info on what peyronies treatment regimen I need to adopt to affect a positive result. Your opinions/suggestions please.

age 67

Greetings Ralph,

You need to spend some time reading the PDI website to educate yourself in this method of using Alternative Medicine to increase your ability to remove the Peyronie’s  plaque or scar from your shaft.  We have literally over 500 of pages of information telling you how to help your Peyronie’s disease.  I suggest you start at least with these few pages from the PDI website:   Start Peyronie’s Treatment and Dosage for Treatment of Peyronies Disease There are many others that you can use to get grounded in Alternative Medicine treatment, but these two are a good start. 

What is the dosage of therapy that will improve my Peyrnonie's disease?

I am taking a combination of Neprinol, Vitamin C and Vitamin E. Can you advise me of a good number of each to be taken per day? I am currently taking 6 Neprinol per day, 3,000 mg of Vitamin C and 800IU of Vitamin E per day. Is this a safe amount that will effect Peyronies disease?


As I write repeatedly in these commentaries, there is no way to know ahead of time if any therapy plan is going to be effective for any particular person’s Peyronie’s condition or what dosage will work for you.  This is why it is essential each plan should be as varied and aggressive as possible, and that it is followed faithfully each day.  Because you will be able to monitor the size, shape, density and surface features of your scar before therapy begins and as it continues you will know whether your plan is working.  If it is working, you continue following your plan. If it is not working, you slowly increase the dosage of your plan until you begin to notice changes in the scar.

It is essential that you not just take your various supplements, but that you “work” your plan.  The PDI concept of determining the dosage of Alternative Medicine to treat Peyronie’s disease is based on a simple system followed to prescribe drugs in medical practice. 

This is how your medical doctor fine-tunes the dosage of the drugs he/she gives you:   Your dosage is started based primarily on your age and body weight for that particular drug – everyone starts at about the same dose, but it will change based on response to the drug.  You take the drug as prescribed, you return in a week or two and your doctor asks you questions and examines you to see if your symptoms have changed.  If your symptoms have been reduced to your doctor’s satisfaction, your dosage is kept the same.  If your symptoms are the same the dosage is either increased or you are given even more drugs.  You now taken an increased drug dosage as prescribed, you again return in a week or two and your reduction of symptoms is determined.  If your symptoms are now reduced your dosage is kept at this higher level.  If your symptoms are the still same the dosage is once more increased or you are given even more drugs.  This goes on until your doctor thinks your symptoms are under control.  This is how medicine is generally prescribed. 

You can use the same method to determine how many and which of your different therapies to use to change the size, shape, density and surface features of your Peyronies plaque and hence to reduce the curved penis that the scar causes.

As you take the dosage of the Alternative Medicine therapies you are using you monitor the size, shape, density and surface features of your Peyronie’s plaque or scar, just as a doctor would.   If your scar shows improvement (smaller, softer, a different shape, more difficult to locate or you have signs of the scar “falling apart,” you keep dosage the same.  If your scar is the same size and shape, just as hard and just as easy to locate, you slightly increase the dosage of what you are taking or you add new therapy to your plan.   You compare your scar every 10-14 days, looking for positive signs of scar reduction.  This pattern of increased therapy continues until you find that your scar has begun to improve.

You do not just start popping a predetermined number of pills each day hoping that you get better.  You monitor your scar for positive scar changes and you are fully aware what it will take to make it happen.  This is PDI method of Peyronie’s disease treatment.  

The Neprinol, vitamin E and C dosage you are taking is very common, and might even be a little low in regards to Neprinol.  Please refer to the notes and detailed instructions you were given about taking Neprinol when you received your order from PDI.

If you have specific questions about altering your Peyronies treatment plan please contact me directly.   TRH

Would PDI penis stretching technique help a congentially curved penis?

I've had a genetically caused curved penis all my life, but as far as I know, i don't have Peyronies scaring. Would your your penis stretching technique help my condition?


Please see my prior response to a similar question at, Stretching a Congenital Curved Penis.

In the last several weeks I have heard from a few more men who also have moderately bent penis they were born with – congenital curvature of the penis.  All have found improvement,e specially those who use Neprinol as part of the plan of care.   TRH

What do I start doing to prevent my Peyronie's disease from getting worse?

I was just told last week that I have pd..I have some pain that is light, no curving, but my erections are weak on the left side at the base with some mild ED. What do I start doing to prevent it from getting worse?  I saw my urologist who told me to take vitamin E 1000 IU daily.  Please advise me to help it not get any worse…thanks

Larry Baldwin

Greetings Larry,

I have never seen vitamin E by itself help anyone with Peyronie’s disease.  Vitamin E is a great therapy but it must be combined with a variety of other therapies to make a positive and helpful impact on a difficult problem like PD.  Besides that, you cannot just take a general or lesser grade of vitamin E and expect it to work for you;  a pharmaceutical grade is required.  PDI has two great therapeutic grades of vitamin E available on the website.

You should by reading about Peyronie’s disease on the PDI website, especially starting with the page Start Peyronie’s Treatment.   

When you have a specific question about treatment of Peyronie’s disease please let me know.   TRH

Can I take all my Neprinol capsules at one time?

I am taking 6 Neprinol capsules per day, along with 3,000 mg of vitamin C and 800 mg. of Vitamin E. Question: Can I take all Neprinol capsules at one time? I have been taking 3 in the morning and 3 in the afternoon on an empty stomach.



There is nothing basically wrong with taking six Neprinol at a time; many people do this without a problem.  The question is whether you, in particular, can or should be taking that many at a time.   For some people taking six Neprinol daily is excessive, while others can do it easily.  Most men who make progress eliminating and controlling their PD scars take around 10-16 Neprinol per day always with a wide variety of other internal and external therapies.   But as far as Neprinol is concerned, the real question is if this is a good dose that you can tolerate while you attempt to eliminate your Peyronie’s plaque.   I suggest that you attempt to slowly work your way up to six Neprinol at a time, since you are only taking three at a time now.  How this is done has been explained to you in the instructions you were given when you placed your order for your PD supplies.

When you ask if you can take all six Neprinol capsules at the same time, I must ask you why you want to do take your entire daily dose at one time.  If you want to do this merely for reasons for convenience (getting it over with and not having to bother with them for the rest of the day), then I must tell you I do not think it is a good idea.  The problem is that by cramming all your Neprinol into one small part of your day then you are leaving a larger part of the day when you have no Neprinol in your blood stream; you want to always keep some Neprinol working for you all day long by taking it often throughout the day.   The question is how much that should be.   For this reason if you are going to be taking only 6/day, then I suggest you continue to take them as you are now doing it.    TRH

Will a combination of Neprinol and vitamin E be effective for my Peyronie's disease?

Do you think that a combination of Neprinol and vitamin E will be effective in helping my Peyronie’s disease?


There is no way to tell ahead of time if any Peyronie’s treatment plan will be effective.   No matter what plan you start with, it is always a guess to know at the start of care if it will help.   The eventual treatment plan a man uses to eliminate his PD is determined by its ability to influence the PD scar.  Each person has different needs, and this prevents one treatment idea from being the solution for everyone.    It is necessary to evaluate the effectiveness of any plan by looking for changes in the size, shape, density and surface features of your scars while you following your treatment.   You can start with any type of plan you believe might help you, but it is the response of the  scar tissue that guides and determines type of therapy that is used and at what dosage.

Your question tells me you have not spent much time on the PDI website.   You really should go over the PDI home page and follow the links you will find there.  If you are interested in recovering from your PD it is a great way to get an education how Alternative Medicine can be used to increase your ability to heal and repair the Peyronie’s plaque that is causing your bent penis.

Using Neprinol and vitamin E is a small combination that is far too limited to reach into the problem of Peyronie’s disease.  I have never heard of anyone who used this combination and got results.   As an example, if you look at the PDI small plan you will see there are seven different ingredients in that plan – and it is called small.   I am fully aware that many men can have financial problems that limit the amount of therapy they use, yet these same men also want a Peyronie’s treatment plan that gets results.

You see, it is not really what I think about using Neprinol and vitamin E that is important.   All I can tell you is that no one has ever told me that taking only these two therapies has helped his PD.    Usually, the plan must be larger to be effective.   How large does your plan have to be?   I don’t know.   You have to figure that out for yourself while you are working with your problem.  I suggest you start here  Start Peyronies treatment  to  learn how this is done.   TRH

Would my doctor recommend your treatment for Peyronie's disease?

Dear Dr. Herazy,

I’ve been all over your web site and read all the amazing testimonials. I’m 54 and I’ve been suffering with Peyronie’s disease for years. I have not been regularly intimate with my wife for years now, and she recently told me intercourse was too frustrating for her due to the challenges we deal with due to my condition. That was hurtful, as if I haven’t already lost all self confidence. Anyway, you may have heard of my doctor, Dr. Ridwan Shabsigh.

I have already been through three rounds of penis injections with little or no results. Dr.Shabsigh has told me to consider surgery.  I need to do something as I can’t continue to live this way, and my marriage is just about shot.

Dr. Shabsigh is considered to be knowledgeable in the area of PD & ED.  Do you know him?  Would he recommend I try your treatments? I really need help. Please let me know what you think.

Thanks very much,


Greetings Tom,

No, I have never heard of your doctor.  I have no idea what he would think of using Alternative Medicine.  However, if it is his idea to think that sticking multiple injections into a penis that already has Peyronie’s disease is a good way to treat this problem, then he is likely to follow the standard medical line of thought about treatment.  

If you want to really get some help beyond the standard medical concept of risking additional scar formation after surgery on a penis that has already demonstrated the tendency to create excessive scar formation , then I suggest you spend some time reading the PDI website.    The PDI website is full of useful information if you take the time to read it.  When you have a specific question about Peyronie’s disease treatment please  let me know.  TRH

Are there supplements to prevent me from contracting Peyronie's disease?

Hi Dr. Herazy.

I don’t have PD, but do have a slight curvature to the left. I had a multitude of sexual problems at one time (needed penile revascularization operation for ED)  and as a result am very paranoid of developing a condition like Peyronies.

The testimonials on your website were very encouraging to read to say the least! I am wondering if there are any supplements I could purchase that would help prevent me from ever contracting the disease?

Best of luck to you in your continuing work to battle this terrible condition.

Thank you kindly,


Greetings Ian,

Prevention is an area that is not only completely untested, but next to impossible to prove.  As a suggestion I would consider trying Neprinol for a few months to determine if you can realize some indirect health benefits like improved circulation, increased stamina, reduced blood pressure, etc.   TRH   

Can my urologist prescribe PDI Peyronies treatment so my insurance covers it?

Can my urologist prescribe products from your catalog so my insurance covers it?


While your idea makes a lot of sense, you must realize that insurance companies do not make decisions based on what makes sense; they decide based on popular medical thinking; insurance company policy is dictated by standard medical ideas.   Your urologist can prescribe anything he/she wants to do, however that does not mean your insurance company will have to pay for it.  Insurance coverage does not work that way.

Using nutritional therapy products to increase your ability to heal and repair the Peyronie’s plaque might make a lot of sense to you and me, it is not standard medical thinking.   Standard medical thinking is to allow the curved penis caused by the Peyronie’s plaque to get so bad that it is treated by a $30-40,0000 Peyronie’s surgery.  Rather than attempt a brief therapeutic trial of natural vitamins and enzymes over 3-4 months that might cost less than a $1000, the insurance company would rather spend a lot of money to cut on a man’s penis and run the risk that it could make his problem worse.

I suggest you talk to your urologist to see if he would be receptive to your idea.  Who knows?   It might happen that you get lucky with your insurance company, and you get your Peyronie’s disease treatment reimbursed.   Strange things happen.   Let me know how it turns out.  TRH

Would Neprinol work on my Peyronie's disease?


I’ve had Peyronies now for roughly 10 years. I passed a kidney stone in my 30’s and it jammed at the end of my urethra, I squeezed it ,and it passed. But for a month my penis killed me. It eventually shrunk to about 3 inches, from 7  1/4 inches . Ive tried everything. I went all natural. vitamin c, 1000mg , omega 3 1200mg, vitamin e 1000 mg, l-arginine, ginkgo biloba, saw palmetto 1000mg, and flax seed oil, 1000mg gotu kola.  All have helped get at least 6 inches in length back after 10 years.

My love life suffered at first, but we overcame things. I would like to get the other 1 1/4 inches back. Right at the tip, just behind, it curves up around 30 to 35 deg. I can feel the hard plaque still. It just won’t soften up any more.

Would Neprinol work, or do you have any suggestions on how to finally rid my self of this man destroying dilemma?  I’m 45 now, I would like to keep going if you know what I mean.

Thanks.  Any suggestions would be a great help.


While I realize you have probably just discovered the Peyronie’s Disease Institute website on the internet, my first suggestion is that you stop playing around using different herbs and supplements that have not been shown to be helpful for treating PD.

“Going natural” is not the key to successful Peyronie’s treatment; you have to use the right products and use them in the right way.  It looks to me like you just started using anything that might have had some positive things written about it, and hoped it would help your problem.   You have not “used everything.”   You have only scratched the surface.   You have approached your problem from the wrong direction and gotten lucky that some of the things you did  might have helped you.   Had you spent that same time, effort and money using the products from the PDI lineup for your Peyronie’s treatment I believe you would have been far better off today.

I suggest you get on at least the PDI medium plan along with the PDI gentle Manual Penis Stretching CD video and use them faithfully for a few months.  It is important to use the exact therapies from PDI because not all brands of Alternative Medicine therapies are of the same quality or potency.   You cannot walk into the average vitamin store and expect to get good quality products that will do the job for you.  It is amazing and appalling that many vitamin shops sell such low quality items.

Your question about Neprinol shows that you do not understand how to use Neprinol and that you are again approaching your therapy from the wrong direction.   You need to spend more time reading what is on the PDI website to learn how to go about successful Peyronies treatment. 

When you order from PDI you will receive specific instructions how to use everything that you order for the best possible treatment of Peyronies disease.   Let me know if you have specific questions about helping your problem.   Good luck to you.   TRH   

What is the best Peyronie's treatment?


I am from Dubai.  My problem is like this:   Peyronie’s disease with left lateral (side) penile curvature and constrictive ring deformity causing hourglass close to body. No pain up to now during sex.  I find that my penis  is now shorter by more than one inch.   I took vitamin A & E but it did not help.  What is the best Peyronie’s treatment?   Thank you.

Greetings to you in Dubai,

I am sorry to learn about your problem.   

Taking only vitamin A and E is seldom effective because it is much too limited or narrow in its attempt to help you heal the PD scar.  The best Peyronie’s treatment is not any one therapy, but a combination of several – sometimes many therapies that work to assist your ability to remove the foreign Peyronie’s plaque or  scar tissue from your body.

Please do not think my answer is silly or insensitive.  Allow me to give you an answer that will tell you exactly what you need to do create the most effective therapy plan for your condition:  The best plan to treat your Peyronie’s disease is the one that you create that causes your body to break down and absorb the foreign scar material.   The best Peyronie’s treatment plan appears to be different for each man.   I do not know what you need to do to make this happen, but I can tell you how to figure this out for yourself. 

If you follow these steps you will do as much as you possibly can to be successful over your Peyronie’s problem:

1. Learn as much as you can about the natural treatment of Peyronie’s disease from the PDI website.  The more you understand the better your treatment and your results will be.

2.  Go to Start Peyronie’s treatment to see the basic outline of getting started with care.  Follow those instructions your read about.  

3.  Determine the size, shape, density and surface features of each PD scar you can find.  If you do not know how to locate your PD scar(s) send me an email and I will give you special help to determine where it is located and how to evaluate it.  This information is critical since you will use it to measure the progress and effectiveness of your Peyronie’s treatment plan.  Without this information you are only guessing about your treatment. 

4.   Monitor your PD plaque for changes as you follow your treatment plan.   If your scar or plaque changes size, shape, density or surface features while you are using your treatment plan, there is no need to change it; you simply continue to use that plan for as long as your scars continue to reduce. If your  scar DOES NOT CHANGE size, shape, density or surface features while you are using your treatment plan, you must increase the plan by either increasing your dosage of therapy products or increasing the variety of treatments you are using.  When you get to that point I will offer you ideas and information so you will know how you wish to proceed. 

Please let me know if you have an questions about how you wish to proceed.   TRH

How long until I see any improvement with my Peyronies problem?

I’m 18 years old and I have PD. I think I had it for 2-3 years, really not sure. It curves up from my pelvic bone to the middle and curves down from the middle to tip. So it kind of looks like an arch or rainbow. It also looks really dark, I’m white Italian and it shouldn’t be really dark like that.

I really don’t want to go to the doctors, I asked to go to the urologist but kept getting questioned why. I came to the conclusion that I’m probably not going to go so I want to help myself.  I want to buy “Vitamin E: Unique-Oil – 1 oz pump bottle”, “DMSO – PMD DMSO Gel”, and “Super CP Serum”.  I been using vitamin e capsule gels and using the gel inside as a moisturizer with baby oil for the past few days.

I want to know how to use the vitamin e properly for your mixture. Do I mix them all together and put it on? Do I use them one at a time? Do I have to be flaccid? Do I use after shower I get out of shower and leave on overnight? Also, how do you rub it in and for how long? Will the box definitely be “Discreet Shipping” even if I don’t buy a plan and just those 3 bottles?

I live with my parents and my brothers, sister and my friends are constantly over so I don’t want anyone to see the box if I don’t get it first. I can just tell my mom the stuff is for my scar and my face because I used to use the capsule gels for that.

Also, how long do you think until it fixes it and how long until I see any improvement? I want to get with a girl and embarrassed to get close to her because of it.

Thank you


Greetings young man,

You need to get over your embarrassment and seek out a medical opinion and have your condition formally diagnosed. 

Why are you mixing vitamin E with baby oil?   Please use the products as instructed when you receive your order from PDI; all products come with complete and correct instructions for use to treat Peyronie’s disease. 

Using only DMSO, vitamin E oil (Unique E) and copper peptides  (Super CP Serum) is a very limited and lopsided approach to good Alternative Medicine treatment; good treatment usually demands both internal (PABA, vitamin C and E, systemic enzymes), as well as external therapies.

Yes, all products received from PDI come discreetly boxed, with no outside identification that would embarrass you.  However, inside the box we freely identify and discuss Peyronies disease.

There is no way ahead of time to tell you how long it will take to recover from your PD, or even if you will do so.  It is a very difficult problem to remedy. Get your parents involved in your treatment so you are not doing this alone and you are able to mount the kind of aggressive treatment that is usually most effective. TRH 

Did my Dupuytrens and Peyronies start from hand trauma?

hello –

at 43 yrs old, i had no Peyronies symptoms. i injured my hand, and it required surgery to insert a couple of screws. when the cast was removed, i noticed a bump in the palm of my hand. about a month later, i noticed Peyronies plaques/scarring.

my primary care physician diagnosed me with Dupuytrens and Peyronies.  have you ever heard of this being triggered this way? i don’t think it was a concidence – not sexually active – no trauma occurred in that area. i had extensive swelling in my arm immediately after surgery from a nerve block that was used, and i can’t help but think that might have played a role. my primary care doctor thinks the surgery triggered some sort of systemic fibromatosis condition.

wondering what your thoughts are on this. this occured 3+ yrs ago, and there really has been no change.

thank you



Yes, I have heard of this sudden and widespread type of onset in which both Dupuytren contracture and Peyronies disease start at the same time from trauma.  In a few cases the trauma was to the upper extremity and once to the penis.  You might also have developed these two problems due to drug side-effects.  Since you did not mention your drug intake history I can only speculate, but there are certain medications that are know to cause both DC and PD; certain blood pressure, tranquilizer and a few other categories of medication can trigger a similar systemic fibromatosis.

If you have not noticed any change in three years with either problem you probably will within a short time since both conditions are progressive, although the rate might be slow.

Your real concern at this time should be directed toward elimination of these problems.  Please review the DCI and PDI sites for Alternative Medicine treatment options to increase your  ability to heal and repair these tissue changes.   TRH 

Is there a treatment to improve my Peyronie's curved penis?

My pain and scar are gone.   However the curvature remains.  Is there a treatment to improve the curvature?  Thanks.


I am happy for your apparent progress over Peyronie’s disease, although I think you are assuming too much. 

When you ask this kind of question it tells me that you think of your scar and penis curvature as two separate things.  That is not the case.  The scar and curvature are directly related; the scar is causing the curvature, and without the scar you would not be bent.    The very best treatment, and the one that makes most sense to improve your curvature is to get rid of the cause.  In this case, the treatment to improve the curvature is to get rid of your Peyronie’s scar.  

While I am sure you are correct that you have noticed reduction of your scar, and perhps you are not even able to find your PD scar any longer, in order for your shaft to still display a curvature there still must be some remaining scar material present within the tunica albuginea.   Sometimes the scar that remains is so greatly reduced or perhaps deeper than you can easily locate, but something must be causing the penile deformity that you still exhibit.   If you did not have some Peyronie’s plaque or scar still in the penis, there would be no explanation for the curvature. 

I suggest you stay on your treatment plan to get rid of your bent penis.  Perhaps vary your treatment a bit while still following the basic outline that brought you the significant reduction of the scar, so that you can totally eliminate the remainder of it and completely reverse your curvature. 

If you need help modifying your current plan to clean up the last part of your scar please send me the complete details of your current Peyronie’s treatment plan and i will be happy to make a few suggestions to improve what you are doing.  TRH

Follow up: Is it possible to urinate the Peyronie’s plaque out of the body?

Dr. Herazy,

Phil F. here, in reply to your response to my
recently posted question: Is it possible to urinate the Peyronie’s plaque out of the body.

I want to thank you for your prompt, direct and most helpful reply.

FYI, it turned out that a second, follow-up urine
culture indeed revealed an infection … enterococ-
cus faecalis. A 5-day regimen of Cephalexin seems to have taken care of it, fortunately.

As for the Peyronie’s Disease, well, I continue to weigh my options ….

Thanks again!



Greetings Phil,

Glad that you got that 2nd urinalysis and that it led to you getting the right kind of help.   

From what I can see from my vantage point of hearing from men from around the world. there are basically three options:  wait to see if your Peyronies gets worse enough to warrant surgery; try an unapproved drug in an off-label application that does not have FDA approval; try to increase your body’s ability to heal and repair the PD scar.

Let me know if you have any questions about using the PDI therapy concept for reversing the scar formation.  TRH 



Corpora cavernosa and the tunica albugnea in relation to Peyronie's disease

This is an anatomy question based on the two illustrations from your website.The first illustration of the inside view of the penis is one of the best I’ve seen. I particularly like the picture in the left corpus cavernosum showing a lattice like structure.

The second illustration has three parts (a,b, and c. Part c shows a penis curving upwards. When looking at the left corpus cavernosum in Part c, there is what appears to be a series of almost parallel squiggly lines. I’ve seen these lines in numerous anatomy illustrations, but have never (ever)seen anyone actually label what these lines are.

As the tunica albuginea is supposed to be smooth, I find these lines confusing. Do these lines represent the lattice like structure underneath the tunic. Or do they represent veins? Just what are these squiggly lines trying to represent?



Greetings Rob,

Great question; thanks for asking.  I always enjoyed the study of anatomy when I was a student; a fascinating and exacting subject that is the basis of understanding disease and our effort to return to health.

For those who do not know the picture Rob is  referring to, go to Peyronies Penis Anatomy.

The wavy or wiggly lines that Rob is referring to are simply what the artist drew to represent the walls that make up the caverns or chambers or cavities of the spongy tissue of the corpora cavernosa.  You are just seeing the cut ends of those chambers represents shown in Box B that are shown as wavy lines in Box C because those same structures are shown from a different perspective.  These wavy lines are similar to a blueprint of a house where the architect draws a series of straight lines to represent the various walls that make up rooms, hallways, closets and outside periphery of the structure.  TRH

What about the use of emu oil for treatment of Peyronie's disease?


I read about DMSO’s ability to carry into the skin. Emu oil I have heard also does this. Do you have thoughts on this? I wonder which would be better/more effective? Emu oil comes from a bird’s skin and DMSO is a wood-processing by-product. Neither one sound very appealing to me but the bird skin at least seems a bit more natural.



Most medical usage of emu oil is for the topical treatment of skin conditions (hives, shingles, psoriasis, etc.)  and other problems (arthritis,weight loss, earaches, flu symptoms, etc.)  

Little serious investigation has been done about the carrier ability of emu oil to bring chemicals and drugs it is combined with into the body, as DMSO does.  

from my experience i have found that many men who have attempted to use emu oil in this way to treat their Peyronie’s disease and usually disappointed, and only make progress when they switch over to using DMSO as a carrier.  TRH

Question about Whey Protein Supplement and Peyronie's treatment

Hello Dr. Herazy,

I avoid mild and eggs and soy products so that I can further help my body heal my Peyronie’s issue. However, I enjoyed the body building benefits of these foods and now I am in search of a body building product that will allow me to increase my protein intake. Most of these kinds of products include milk, egg, and soy. I used to use the Gold Standard 100% Whey Protein but, alas, it contains milk, egg, and soy (lechitin). Is this Whey Protein product as harmful to me as I think or can I go ahead and use it as a protein supplement?



I suggest you use a small amount of your Whey Supplement powder to determine what effect, goodor bad, it might have on the size, shape, density and surface features of your PD scar.  TRH

Is it possible to urinate the Peyronie's plaque out of the body?

Hello Dr. Herazy,

I have had Peyronie’s Disease for the past 18 months, with a penile curvature that is quite severe.

From 9/15 to 11/8/11, my urologist had me on a regimen of twice daily applications of Verapamil 30 ml Transdermal in PLO gel,80 mg/ml. As there was no discernible change in the curvature over the course of almost two months, it was decided to discontinue the Verapamil regimen.

However, since stopping, my recent urinations have contained a variable degree of light colored tissue-like particulate matter. Thus far, urinalyses have yielded nothing pathological, and thus the cause remains unknown.

My question is therefore: Is it possible that what I may be expelling in my urine are pieces of loosened plaque that have made their way into the urethra and out through the penis? My urologist thinks not, but the pharmacist does not rule out the possibility … despite believing it to be unlikely.

I might also add that the more such particulate matter being discharged during urination, the more discomfort I experience in the tip of the penis …. along with the occasional sensation of not having fully emptied my bladder.

Any answers, thoughts or recommendations would be very much appreciated.

Thank you,

Phil F.


Greetings Phil,

There is no anatomical connection between the opening of the urethra and the tunica albuginea of the shaft where your plaque is located.   Your pharmacist might be a great pharmacist, but knows noting of anatomy. If you actually did have a direct connection between the two you would be in the middle of a massively painful and bloody medical emergency, and you are not.

My guess from this end, with the limitation of knowing only what you have told me, is that you have an infection in the urethra – in spite of the negative urinalysis tests.  There are always false positives and false negatives in this kind of testing, and it is my guess that this is the case with you.  I suggest you go back to tell your urologist that your symptoms persist and that you would like another urinalysis done ASAP. 

After you get that situation cleared up I suggest you go to the PDI website to start some Alternative Medicine Peyronies disease treatment.   TRH



What do you think of adding potassium iodide (SSKI) to my Peyronies treatment plan?

Can potassium-iodide mixed with DMSO speed up my healing of my scar?

I am applying DMSO together with Unique vitamin E and Super CP Serum daily to my scar as you suggested.

However recently I read a post that claims adding potassium-iodide (also called SSKI to the DMSO will help reducing the scar as well. Is this something you could confirm as a good strategy?




Greetings Rik,

No, I do not think it is a good strategy.

I have heard of SSKI (potassium iodide) for treatment of Peyronie’s disease.  That information comes from the website of Jonathan V. Wright, MD of the Tohoma Clinic.   He has some interesting things to say about it.  He is an intelligent and provocative author.  I like his work, and he is a good man.  I just have a difference of opinion with Dr. Wright in this particular area.

However, there is a problem with the idea of using SSKI for PD:   Dr. Wright is the only one saying it.  His concepts and opinions might very well be correct, and SSKI might be the best therapy imaginable for PD.  But I doubt it.  Why?  Because, from what I can determine, there has been absolutely no research or study of this subject for PD or DC by anyone at any time.  It is all conjecture and theory, even if it is interesting and makes sense, it is still unfounded at this time.  It is a far more unfounded idea than anything you will find on the PDI website.

The intent of PDI is not to present all Alternative Medicine therapies for your review just because they are non-medicinal in nature.  We do not advocate what we advocate simply because they are “natural” or easy to acquire without a prescription.   Those therapies you find on the PDI website are there simply because there has been research (often a lot of it) that supports the use of a particular Alt Med therapies for PD, in spite of the fact that there is in addition contradictory research to the positive findings.  We take the position that a least we are using those therapies that have satisfied a considerable percent of researchers to suggest the possibility of adequate efficacy.  If taken as a group, in aggressive doses and high combinations, we stand a good chance of creating sufficient synergy to initiate a healing response in the body.

SSKI does not fall into that description.  It has not been studied.  When it is studied and receives a positive review from several independent sources we will likely consider adding it to the lineup.

Keep reading Dr. Wright’s articles, he has a lot of good information for all of us.

In the meantime, why are you still looking at things that are so marginal when there is a wide swath of therapies with some level of proven veracity at your disposal that you are not using?         TRH

How high can I increase each product beyond the instructional use to see improvement?

I ordered your medium plan.. I was just wondering in relation to the sulfur, Fibrozym and Nattokinase is better to take each one of these separately at different times of the day or should I combine them for better results..I’m cautious to combine because one might negate another’s effectiveness. Also under the instructional dosage I have had limited results.   How high can I increase each product beyond the instructional use to see improvement?



Each therapy product should be started at the dosage recommended on the label, just as you were instructed by the various papers that came with your order.   If that dosage, when combined with the other therapy products in your plan, proves to cause your PD to improve you simply continue to stay on that dosage until your scar is absorbed by the body.  If that dosage, however, has no positive or beneficial effect on your Peyronie’s disease, then the dosage is slowly increased according to the directions sent to you when you placed your order.  Men usually do not have to go very high to see positive changes, and seldom near the upper end of safe dosages since they are combing other therapies.  The most common problem from taking a higher dosage following the PDI plan is that of nausea or diarrhea, that is usually mild and easily controlled.  

You can take your MSM (sulfur) product at the same time you also take your Nattokinase and Fibrozym.  No need to separate the time you take them.   TRH

What can I do for my penis pain and hourglass deformity?

Dr. Herazy,

About 5 years ago, i was 20 years old. I had a healthy penis and a healthy sex life. I had some hair follicles/ bumps on the under side of the shaft that i would occasionally ( for some odd reason ) pick at. I had no problem with them aestetically. You could barely notice them even if you were looking for them. I just would pick at them like someone picks at blackheads or pimples on their face. I picked at one bad enough to where it scabbed up, which i had never done before. When this happened, before it had a chance to heal ( maybe 3 or 4 days later) i was picking at the spot again, and a little white nodule appeared and i scraped at it thinking it was a hard secretion of some kind. Instantly i lost feeling in my penis, and i panicked. There was not really any pain, but i didnt feel anything, and i could not get an erection. I could touch my penis with my finger and in some spots could not feel the touch at all and in other spots it was just dull. I went to the emergency room worried that i did something serious even though everything that happened was pretty superficial and just below skin level. After talking with a doctor, he couldnt explain why i lost feeling, but he assured me that i could not have damaged any nerves that shallow, and to relax and soon enough i would be able to get an erection. So, i did just that, and what do you know, the next day i relaxed and was able to get an erection. The problem was i still couldnt feel things as well as i use too. I figured that would pass as well. For the next few months i dealt with this minor nuisance. The amount of feeling i had in my penis would fluctuate day by day, nothing to serious, but something wasnt right. Also, the wound never seemed to close up correctly. To this day, 5 years later, it looks like an open hair follicle where the skin did not heal correctly and i can still see the little white nodule that i once picked at. One day a few months after the initial incident me and my girlfriend, now my wife, had sex three times. The next day i woke up, and my problem had gotten worse. The feeling of numbness was now worse, and now the head of my penis had a lot of numbness, which i forgot to mention was not the case previous to this. Also the head of my penis became discolored suddenly, overnight. It was just a slight discoloration around the sides and back of the head. The middle top part about the same size area as my finger tip was still the same color. This one area had normal feeling, whereas the slightly discolored area had much less feeling. There was a definite correlation. The day after that when it did not go away i scheduled an appointment with a urologist, and i went to see him that week. He basically told me nothing was wrong, and it was in my head. He told there is no way i damaged my penis from what i described, and there was nothing wrong with the color of the head of my penis. I understood that it was within a normal color range, but what i tried to explain to him is that my penis head was usually just a solid pink same normal color. Overnight, this tinted darker discoloration appeared, and it correlated with less feeling in these areas. He completely dismissed the notion. To ease my worries he sent me to a neurologist. All this guy did was have me do some standard normal tests someone would test for normally with a neurological injury and tell me i was fine and collect like 250 bucks of my money. No help at all. I gave up for the time being, and just lived with the difference in feeling. Sex was still good at times, but not so good at other times, and now after sex there was a recover process. I use to be able to have sex every day or two times a day or masturbate early in the day and then have sex at night. I couldnt do this anymore. There was never any pain during sex, but after sex there was irritation and soreness, and it usually took a day or so to recover. So i would just have sex once or twice a week. The sex itself would not hurt me. Ejaculation is what seemed to cause the pain and irritation inside of my penis. For maybe a year it stayed around the same. Then all of a sudden again, there was a new change. I masturbated earlier in the day, and then had sex at night and all of a sudden it got worse the next day. The feeling on the surface was worse, and now i would have weird feelings throughout the day where i would feel like i was on the verge of ejaculating just riding in my car, or walking around. There was something going on inside, possibly with my erectile tissue, causing these feelings. Also, i stopped masturbating for a long period of time after this because it appeared to make it worse at the time. I would ejaculate by becoming aroused and just touching my penis when very aroused due to my new feeling i was able to achieve this because i could now ejaculate easier and faster, with no movement of my hand on my penis. In the past, before my “injury”, i could sit around all day and try this if i wanted to and nothing would happen. This was not a good thing. When i would have this feeling on a regular basis at work or in a car, it become extremely annoying, like an itch. Also, the pain and irritation was worse now and become a nuisance, and now all of a sudden there was a new symptom more then a year in. The area right under the head of my penis seemed to be more hardened. Especially after sex. I could squeeze the bottom half of my penis with my thumbs with it soft and it was really soft and spongy. Above that from an inch below the head up to the head it was much harder all the way around. Especially shortly after ejaculating when it was the most irritated. For a while it seemed to just get gradual worse with the hardness, and the sensitivity and feeling varied day to day, and occasionally it would get much better which gave me hope that it was recovering. I would abstain from sex or masturbation during this time period, but a few days later it would revert back to how it felt before with the lack of sensitivity and irritation. Also, each time my symptoms got worse, i lasted shorter in bed. I would not have much feeling and my girlfriends vagina did not feel great anymore, but because i had that weird tingle that i walked around with all day i would sometimes ejaculate after a few hard thrusts, or i would have to cut it back and switch positions. The sex just was not comparable anymore to how it use to be. Over the last couple years it has been pretty much sustained with no significant change. One this i forgot to mention is i do have two benefits up until now that some others i am reading about do not. number one, i always can get a full erection. Number two, my erection is not curved. Still, the hardness got worse, and there seems to be a few little bumps or nodules under the skin in my upper shaft. Also when my penis is completely hard it looks straight, the only difference is on the right side of my upper shaft even though my penis does not bend, it is abnormal in the sense that it seems that the line is not smooth and straight up to my head any longer. It is ridid and dips in and back out slightly, not even really visible without pointing it out. Also when i am getting erect but not fully erect the penis will be bent to the right in a way that it never use to, but when i am fully erect there is no bend. Also, when it is in between flaccid and full erect, i can see the hourglass shape and a slight dip on the right side of my shaft in the middle right at the beginning of where the plaque seems to be. I think that i dont have a bend because the plaque is on all sides, thus the hourglass shape. My most recent development that is scaring me more then any of the other is there is now constant pain just on one side of my penis. It is after, during, and before sex. My problem would never bother me during sex previously, it would just shorten the length of time we could have sex and afterwards be irritated and require a day or two of recovery. It effected my sex life, but there was no pain during sex. Now, all of a sudden, 5 years later, this disease still continues to every once in a while get worse. The upper half of the shaft seems to get harder
, the bend seems to be more when flaccid and in between flaccid and erect, although there is still no bend while erect. Worst of all this pain now is scaring the shit out of me. I forgot to mention that i went to that same urologist twice, and then finally went to another urologist, and they all blew me off. The one saw me, and then gave me my money back and told me i did not have Peyronies, because i came to him with this diagnosis after my penis started to get hard spots and develop and hour glass shape. Also, it seems my penis has shortened slightly but this does not bother me so much. What does bother me is this new pain inside my penis on the left side that hurts during sex. After 5 years of this disease progressing it really has taken its toll, and for the first time it is now severely affecting sex. Will this keep progressing?  Is there anything i can do?  Does my disease continuing to progress have anything to do with that original wound that seemed to heal weird and remain slightly open? I look down at my penis when it is in pain and i cant fathom what has happened to me. I am 25, and i feel like i have a penis full of damage and scar tissue. Until now, i would have some days where my penis felt pretty good once in a while which gave me hope that this may be reversible some day. Now that hope is gone because this pain and irritation in the left side of my penis deep inside never goes away and its very constant. It just gets worse after sexual activity, and recovers slightly over the next few days. Is it possible the inflammation has caused penile cancer? Should i go back to the doctors again just to have them too me there is nothing wrong with my severely damaged penis? I still hold out hope because i still get full hard erections and there is no bend when fully erect, but all of this numbness, pain, and hardening among many other things is depressing me so badly. After 5 years i thought i learned to live with it, but this no pain i cant take? My main concern is there a possibility that i have penile cancer, since the pain on the left side seems to be worse right at the top of the shaft by one of these small bumps. It is not localized to the spot though, and when i press on the bump, the bump itself doesnt hurt. I wish i could do something to make all of this better, or just take a few steps back to where it was maybe halfway through this process. Any help is appreciated, thanks.



Several of your symptoms make your condition sound very much like Peyronie’s disease (shortened penis, pain, hourglass deformity, presence of “hard spots,” although you report one urologist said you have the condition and another said you do not.  I suggest you get a third opinion to break the tie.   One of these two is obviously wrong, but at this point you do not know which of the two it is.

What you describe does not sound like cancer.

If it turns out you do have PD I suggest you get yourself on an Alternative Medicine plan of self-treatment to increase your ability to heal and repair your Peyronie’s scar – if that is what it turns out to be.

Lastly, if it turns out you do have Peyronie’s disease I doubt it was caused by your picking five years ago at the superficial white spots.  These are known as Fordyce’s spots, and they are common, normal and natural 1-3 mm structures that most men have on the penile shaft and scrotum, of unknown origin.    I speculate that you probably injured yourself during sexual activity and this is the origin of your current symptoms

Please let me know what you learn after your 3rd evaluation.  TRH 

Is it OK to have sex if I have Peyronie’s disease?





There is much to say here.

First, do not stop your sexual activity; it is important that you basically continue as you always have, with the exception that you must be much more careful and defensive with your technique.  This is a huge subject, so perhaps to really understand it best you should get my book, “Peyronie’s Disease and Sex.”  It will help both of you to understand how to have a full sex life in spite of Peyronies.

Fewer doctors are using verapamil because of limited results – and you have seen this to be true for yourself already.  For more information, see my article,  “Peyronie’s and Verapamil.”     

Next, when you ask what kind of Peyronies treatment you can use to help yourself with your PD it is obvious you have not spent any time looking at the PDI website; it is loaded with hundreds of pages of information to answer this question.   To get you going in the correct direct go to start Peyronie’s treatment.  

You must protect your penis to prevent additional injury during sexual activity.  You do not have to worry about light contact or pressure during the day.   To protect the penis during sexual activity we have assembled a great list of effective penis supports that will reduce the chance of re-injury by sudden buckling or bending during intercourse.    Go to Sex Supports and Aids.     You never want to force your bent penis to make it straight.  Once you start treating your PD and you begin to cause your internal scar tissue to get reabsorbed your penis will be able to naturally straighten out.   Before that happens do not apply pressure to reduce your curved penis to make it straight.         

You really need to spend some time educating yourself in this critically important subject so you will know how to protect and assist yourself.    Probably the best single thing you can do to understand how all of this operates and how to help yourself is to get my first book, “Peyronie’s Disease Handbook.”  TRH

Why didn't the first skin graft take?

I had peyronie’s surgery back on 19 Sept 11.  My urologist removed two large masses which he told me was scar tissue. He also said he repaired the areas with grafts. It has been almost two month now and I have a 1 1/2 x 2″ open wound on the shaft of my penis. I continue to keep it clean and bandaged but it does not seem to be healing. I’ve been told by another urologist that I need another skin graft. 

Unfortuntatetly I’m currently depolyed to Afghanistan and not scheduled to return until June.    Why didn’t the first skin graft take?   Is there a risk in waiting until I return back to the states?




Greetings Tony,

Thank your, sir, for standing tall and strong to protect the freedom we all enjoy.   Our thoughts and prayers are with you and your brave comrades.   

There are several possible reasons why your post-surgical wound is not healing, that you should have your doctor explore for you:  diabetes, reduced local circulation, poor wound care, heavy aspirin usage, compromised immune system and poor nutrition.  Any of these can contribute to this situation and perhaps others if someone takes a close look at you. 

The complication rate for Peyronie’s disease surgery is higher than for many other types of surgery.   This is why I always strongly encourage men to do whatever they can to avoid this radical option until all conservative options have been explored.   

The sooner you begin your healing and wound closing the better.   If no one seems to be listening to your problem, I  suggest you contact your home town congressman to work to get you some help and attention.     TRH

Is there a "sex toy or tool" to prevent additonal injury to my Peyronie's penis?

Good day! 


Is there any “sex toy or tool” that can help not to get more injured when masturbating?

Thanks for being available to us  PD Warriors.


You are welcome, and thanks for being a Warrior.   It is my pleasure and my obligation to tell people about how to help themselves recover from Peyronie’s disease without drugs or surgery.

For years I have listed a nice size group of such “sex toy’ items on the PDI website because they can indeed protect and support the shaft during intercourse and help prevent further injury when you already have Peyronies.   When the shaft is bent, curved, dented  or narrowed due to the underlying scar material it is extremely vulnerable to injury by collapsing or folding over during the rigors of intercourse and masturbation.  Any man with such a penile deformity should look at these devices to see what appeals to him – and use it to prevent additional harm.   Go to PDI store front and scroll down until you see the penis support devices to be used during intercourse.  

Of course, it is always best to slow down, use a reasonable and cautious technique while masturbating, and use plenty of sexual lubricant to avoid additional injury while masturbating.   Vibrators are always a safe tool to use since little friction or force is used.   TRH



How to know which plan to use for Peyronie's treatment?

How to know which plan is suitable for mein medication section?  My condition is similar to bent on the left and hour glass constriction at the base.  I am 40 years old and using size genetics also.


There is no way to know exactly which plan you should use for your Peyronie’s disease.   You start with a plan that makes sense to you, that you can find time in your day to put to good use, that you can afford the expenses, and you begin care.  As you use that plan you monitor the size, shape, density and surface features of your scar for changes.  If you notice changes in your scar, you continue that plan you are using.  If you do not notice changes in your scar, you slowly increase your plan until you do begin to notice scar changes.  It is not complicated.  

Many men find that their Peyronie’s disease started after using a mechanical penis stretching device.  It is my opinion they are all very dangerous. See  Penis Extender Claims and Peyronie’s Disease.

Please review the PDI website for information about a much safer way to treat your problem.  TRH       

Herbal products to help with ED associated with Peyronie's disease?

I believe I got PD using ED drugs been married 30 yrs & need some erection help. Have stopped using the drugs, can you suggest something herbal I can use to replace them. Thanks Dave

Greetings Dave,

What you report is rather common.  I have communicated with hundreds of men who tell me their Peyronie's disease started after using PDE5 inhibitor drugs (Viagra, Cialis, Levitra); this can happen after just one use or repeated uses.  For more information see Peyronie's disease and Viagra, Levitra and Cialis and Peyronie's treatment and Cialis.

If you go to the PDI shopping cart and scroll about 3/4 the way down until you see BetterMAN and about 5-6 other sex stimulant products. The most important of the group is a product called Stimulin. You would definitely want to include Stimulin with whatever else you use.  

All of these herbal products are much more gentle than your drugs and will not worsen your PD problem.   Many men use them while undergoing their natural Peyronie's treatment plan.  TRH

What is a good vitamin E for Peyronie's treatment?

I was diagnosed with Peyronie's several years ago and my doc told me to take Vitamin E. In a few weeks, the symptoms cleared up. My problem is that I've developed PD again, have seen another urologist who also suggested Vitamin E. The PD seems much worse this time around. My question..if I choose to simply take Vitamin E, can you recommend the exact(and very best) brand, dosage, etc. I'm still sexually active, but it is affecting my sex life and is very stressful. Any help you might offer would be greatly appreciated. Also, I have read/researched at great lengths on your site and may return if you cannot offer a possible solution based upon the info I've provided. Thank you very much, Bobby

Greetings Bobby,

Sorry to hear of your Peyronie's problem.

Vitamin E is one of the cornerstone Alternative Medicine therapies recommended by PDI.  You can read about using vitamin E for Peyronie's treatment on the PDI website.  However, it is not all that is usually needed to recover from this problem.  So often it is required that a man assemble a group of therapies to take all at the same time to finally increase the immune response of the body against this problem.

PDI has a shopping cart from which you can order a great vitamin E product that we have used for over ten years.   Feel free to contact me if you have additional questions about helping yourself with natural therapy.   TRH 

Connection between bladder inflammation and Peyronie's disease?

I have interstitial cystitis that I developed about 2 1/2 years ago where I feel constant low grade pain in my penis – with tender areas of the shaft. I noticed the curvature of my penis has gotten significantly worse with time and erections now are painful and seem to pull beyond the capacity of the ligament causing an upward and left bend. Have you heard of a connection between Peyronies and IC? I am also on treatment for gut pathogens and am concerned about any of the PDI treatments which might reduce my body's immune response since I need it high to fight my gut pathogens. Given this, where is the best place to start? Can I have a phone consult?


Interstitial cystitis is a problem of unknown origin causing chronic and long term low grade inflammation of the wall of the urinary bladder.   In these cases pain is felt during intercourse and in general in other parts of the pelvis, along with pain during urination.   The bladder wall inflammation causes both urinary urgency and frequency up to several times an hour.

Of course I am at a great disadvantage in not really understanding your full history.  What I can tell you is that there is typically no direct causal relation or connection between interstitial cystitis and Peyronie's disease.  However, based on what you have mentioned in your email you make it sound like you have two independent problems going on, and it would seem that if this is true you would probably have to deal with them separately.

The natural Alternative Medicine treatment for Peyronie's disease recommended by PDI would not do anything to reduce your immune response, but would probably enhance and strengthen it.

Probably the best place to start is with a telephone discussion of your problem and to help you develop a viable treatment strategy.  Please contact me at 847-670-8800.   TRH

How do I treat Peyronie's disease?

Within the last two months I noticed that my penis is started bending to the left. I was taking an anti inflammatory for back pain and I’m wondering if the med caused the problem, my penis seems somewhat shorter as well, what can I do to rectify the problem. Richard

Greetings Richard,

The first thing you should do is get yourself checked out by a urologist to determine if you have Peyronie’s disease.

If it happens that you do have Peyronie’s disease you will want to begin a conservative course of care to help your body heal and repair the infiltration of excess collagen in the deep tissue of the shaft. It is this mass of internal scar tissue that is causing your bend to the left. It might appear to be a small point of differentiation, but in Peyronie’s disease the actual problem is the internal collection of collagen under the skin of the shaft that causes distortion of an erection, as well as loss of length and girth, and not the penile curvature; the penile curvature would not exist if it were not for the presence of abnormal deposit of collagen.

I would have to know the name of the medication to know if it is a possible cause of your current situation.

For treatment options, please go to the home page of the PDI website and click on the several links that give helpful information about what you can do to help your body heal and repair PD. TRH

If he discontinues drug use would his penis eventually return to "normal"?

My husband’s penis has become increasingly curved/bent (now about 45 degrees when erect) over the last 8 months. He has been on an antidepressant for about 5 years. He is a traumatic head injury survivor and is on the antidepressant to control outbursts of anger. However, the antidepressant has decreased his sexual function dramatically and the bending of the penis decreases his function further. If he discontinued use, would his penis eventually return to “normal?” He is also on medication for seizures.


You have not stated that your husband has been diagnosed with Peyronie’s disease or not. I ask not only because of the curvature you mention, but also because there is an anti-seizure medication, phenytoin, that has been said to cause Peyronie’s disease.

If in fact your husband does have Peyronie’s disease it will not help him to discontinue any drug that might have caused it. He would still have to undergo Alternative Medicine treatment of the PD in an attempt to have his body correct this curvature problem caused by the internal Peyronie’s scar material.

As an aside, I have communicated with several men with Peyronie’s disease who say that their Peyronie’s disease started with an injury to the penis that occurred during an epileptic seizure that happened while they were erect. You might keep this in mind when you consider another possibility how his PD started.

All patients should check with their doctor before discontinuing any prescribed drug. TRH

Can Peyronie's disease cause a "back-flow" that maintains an erection?

Dear Dr Herazy,

I recently had a cystocopy and developed approximately 2 weeks later hardness in the perineal area of corpus carvernosum. The shaft is still unaffected. However because of the hardness that probably reminds of of a reverse bottleneck I have had trouble getting the penis down after an erection. This is particularly problematic during the night where I wake up from the erections and then have to get out of bed to get it down.

My urologist said that I could have developed developed peyronies disease in the perineal area but I have searched the Internet and have not seen any similar cases. The area covered is around 2 inches. Have you heard about something similar including the decreased "back-flow" following the erections?

I am also worried I could develop a priapism from this condition that would make things a lot worse. Can you make an advice as how to move on?

Thank you very much in advance.

Kind regards



Greetings C,

First of all, I think a few people who read your email would have some questions of his own about some of the terms you used.  So, here is a bit of information about these terms to help understand your email a little better:

1. Cystoscopy – a medical procedure in which a long tube or probe is inserted up into the urinary passage (urethra) of the penis for the purpose of looking into the urinary bladder or the urinary passage, itself.   It sometimes happens that when this is done that the urethra and tissue of the shaft of the penis can become injured, resulting in Peyronie's disease.

2. Perineal area – the region of the very lower part of the pelvis in men that is found between the back part of the scrotum and the anus, and in women between the back end of the vulva or outer lips and the anus.

3. Corpus cavernosum – or corpora cavernosae – one of the two long cylinder shaped masses of tissue that make up the bulk of the penile shaft.  Each corpora cavernosa is covered by a thin tough layer of fibrous tissue called the tunica albuginea that when injured becomes scarred and leads to Peyronie's disease.

4. Back-flow – release of blood that was trapped in the two corpora cavernosa during an erection that creates the hydraulic pressure within the penis to make it expand and hard.

5. Priapism – this is a persistent, and often painful, erection that is considered a medical emergency when it lasts longer than four hours and develops without sexual stimulation.  Priapism occurs when blood in the penis becomes trapped and not able to drain as it normally does. 

OK, now that we have that out of the way, allow me to address a few points you made:

1.  The penis is attached to the front part of the pubic bone in the area directly behind the pubic hair.  If you are an average size male, there is probably 4-5 inches between the point where the penis ends and where the perineal area begins.  These two structures are not connected or related. There is no perineal area of the corpora cavernosa.  Any hardness, mass formation, swelling or abnormality of the perineal area is not related to the penis and is not related to Peyronie's disease. If you truly have a hard mass or lump between the base of your scrotum and the anus I suggest you get it checked out immediately.

2. I know what a bottleneck deformity is in relation to Peyronie's disease, but I have no idea what you mean by a reverse bottleneck.  Please explain.

3. The reason you could not find any reference to Peyronie's disease in the perineal area is that it does not happen that way and it is not possible. 

4.  Your decreased back flow causing persistence of an erection could be related to the mass in your peineal area; for that reason you should see a doctor immediately.

5.  Pripism can occur as a result from many different situations, but not Peyronie's disease:

  • Sickle cell anemia
  • Medications, like Thorzine and Desyrel
  • Illicit drugs (marijuana and cocaine)
  • Trauma delivered to the lower pelvis or spine, or something in that same area causing reduced blood flow 
  • Black widow spider bites
  • Carbon monoxide poisoning

6.   I assume that your doctor did not give you much of the information you have shared here because it is mistaken.  To move forward I suggest you stop trying to figure these things out for yourself and immediately get yourself examined by a competent urologist.  TRH

Stretching a congenital penis curvature

Hi Doc,

I posted a previous question about my congenital curvature downward and you recommended that I purchase the Manual Stretching video, I did, and have been doing the stretches every day and sometimes i have a day or two break which is rare, but ive been pretty persistent.

Do you also suggest I be more frequent? is frequency necessary? Also, I really want to know EVERYTHING possible i can do to lessen my downward curve, stretching or anything else you have in mind. I'd love to start having a more aggressive approach to see some results. Ive been taking neprinol for the past 2 months but ran out of supply, and came to the conclusion i don't' have peyronies so i don't need to take neprinol correct?

Please let me know of everything i can do to help me. '

Thanks so much.



As I mentioned in the reply to your earlier questions, all research done with the PDI Manual Penis Stretching technique was done with men who had PD and were using a variety of different PD therapy programs (vitamins E and C,  Neprinol, MSM, DMSO, etc.).  We have never researched the use of this method against a congenital penis curvature.   I mentioned that I have had men contact me who had a congenital curve and used this technique and got very good results.  That is about what I can tell you directly what I know about this subject. 

I tend to agree with you that Neprinol would likely no be of great use in your situation.  I suppose it is possible that it could help your effort, but I do not see a logical way this might happen, but at this time I just do not see it.

Since you ask about anything else I have in mind that might help you, I believe that the use of topical PMD DMSO with vitamin E and copper peptides does make more sense than Neprinol in your case.  This is conjecture on my part, but it does seem logical to me this should be helpful.  If you agree, then you might consider adding that to what you are currently doing.

Lastly, frequency and consistency of use of the penis stretching work is essential. The more often you apply this gentle stretching work the greater your odds for success.  This is probably the most important element of what you can do to help yourself, so please put in more time applying this gentle stretching.

Please let me know how you progress.  Since this is new territory for me, I would like to know more about what you are doing and how it works out for you.  TRH

Must I accept there is no cure for Peyronie's disease?

Hello Dr. Herazy,

I've had Peyronies since I was 14 years old. There was a blunt trauma, I was too young and shocked to address the issue and chose to ignore it.

Initially, my erections were not greatly diminished. There was a curvature of about 30 to 35% to the left and slightly downward. Erections lasted a little less long and were slightly harder to produce. Urine did not pass as forcefully as it had before.

Now I am 31, erections are much harder to produce, are never full and have significantly less duration. At times there is a slight pain in the penis after ejaculation and urine passes much slower than it use to. I would place the curvature at 40 to 45% and in a more flaccid state. It is very depressing for me because I have only experienced sex with this condition and as it worsens I avoid it and relationships. Surgery sounds horrible and signing up to a treatment plan has me concerned about developing conditions or side effects from the treatments, as I have a lot of life to live.

Is there any hope? Must I accept that there is no cure and what ever options are available will involve sacrifice or long treatment plans?

Suffering Guy


Greetings Suffering Guy,

Apparently you have not spent much time reading the vast amount of information about natural Peyronie's disease treatment available on the PDI website.  

When I developed PD in 2002 I began my treatment with the premise that there is a cure for Peyronie's disease – various authorities will report that from half to 20% of men who develop this problem will undergo a spontaneous remission in which it just goes away on its own.  In other words, the body corrects the problem of the internal plaque or scar tissue in the tunica albuginea, and the scar and the curvature just go away.  that sounds like a cure to me. 

When you read on the medical websites that "there is no cure for Peyronie's disease," what they really mean is that there is no prescription drug available from a pharmaceutical company that has FDA approval to eliminate the plaque in the internal tunica tissue.  While it might be true that "there is no cure for the common cold," does that mean that everyone who has a cold will continue to keep the problem and will eventually die from it?  No.  With rare exception (the very young, the very old, and those who are very weak with severe illness), anyone who develops a cold will cure it usually in a little less than a week.  That is what the body is designed to do to cure itself.  

Certainly, there are some conditions (cancer, multiple sclerosis, Alzheimer's disease, etc.) that are more difficult and more rare to overcome, but for the most part there are a large number of health problems that the body is fully capable of self-repairing.   Where exactly is it written that every case of Peyronie's disease is permanent and beyond the ability of the body to eliminate? I have never read that anywhere, and as I mentioned earlier every authority states that a fair number OF PD cases reverse themselves for complete elimination.   If that is true then the question should be asked, "Why hasn't your body eliminated your PD?"  

For the last 10 years I have spent every day with that question on my mind.  I have developed some ideas and strategies I have seen over and over again that will increase a man's ability to get rid of his own Peyronie's disease.  You can read about a few of these Testimonials of Peyronie's Disease Institute

There is not much I can do to reduce whatever level of sacrifice or time is required for your body to reduce your Peyronie's plaque to the best of your ability.  I hope you think enough of yourself, and are willing to do some work, to bring about your best level of recovery.  If you have any questions about using Alternative Medicine to treat Peyronie's disease please let me know.   TRH

Is it possible to have a penile curvature without having a Peyronie's scar?

Dr. Herazy,

Is it possible to have an extreme curvature in one or both of the blood-filled columns in the inside of the penis without having a scar? I can't find a scar at all. Also, I only have pain (a slight twinge) in the base of the penis and in the curvature?



The only way you could have an extreme curvature without having a scar would be to have a congenital curvature (born with a normal curvature) or to develop some other health problem that would cause additional penile symptoms. 

If you have been diagnosed with Peyronie's disease and you have a bent penis you must realize the penile curvature is being caused by something that was not present before you developed PD.  There must be a reason for the distortion, correct?  In your case, the distortion is being caused by extra fibrous buildup that is very difficult to locate.  This is common in Peyronie's disease; I guess that at least half of men with PD have difficulty finding their scar(s).   In fact, it is so common that I wrote a blog post titled, "Can't find Peyronie's plaque or scar."   You could also read another question and answer, "How do I find my Peyronie's scar?" 

It is typical for someone who has been medically diagnosed with PD to still feel uncertain if this diagnosis is accurate and correct.   It is part of a denial response.  If this is true, you must either make up your mind you will either accept the diagnosis or go to another urologist for another opinion to either confirm or deny your Peyronie's disease diagnosis.  I sense that you are beating yourself up with doubts and endless questions.  At some point you must stop fighting the idea you have PD. You need to eventually take that energy you are wasting on endless worry and use it to do something about your problem.  Some men have a difficult time dealing emotionally with severe penile curvature.  If that is true for you, please contact me for a few EFT sessions and I think I can do something to help you in this way, as I have done for so many other men.   

The pain of Peyronie's disease is quite variable in terms of degree and location. Having a slight twinge at the base of the penis, and within the curvature, is consistent with this problem.  But then, having a great amount of pain at the base or toward the top of the penis would also be consistent since the pain of PD is wildly variable. TRH  

Are there muscles in the shaft of the penis?

Dr. Herazy,

Are there actual muscles in the shaft of the penis, or is it all just tissue?

If it's tissue that I'm trying to heal, then which of your products have you seen to be more successful in taking care of a pivot?

More specifically, my pivot starts small and then makes my penis grow top-heavy as it becomes more erect? Is this common?



There are no muscles in the penile shaft.   The bulk of the penis is made of three cylinders of erectile tissue; two are called the corpora cavernosa and the last is the corpora spongiosum. These long masses of erectile tissue are referred to as spongy tissue, since like a sponge they have large open spaces that can fill with blood and expand during an erection.  Any movement of the penis that occurs when you intentionally contract your lower pelvic muscles comes from the attachment of base or root of the penis to what is called the pelvic sling that contains the pubococcygeus (PC) muscle.  The PC muscle is a what is called a voluntary muscle that works when you want it to work, just like the biceps or gluteal muscles.  It is not part of the penis, but is is closely connected to the base of penis and the PC muscle lifts the penis because of the way it is connected to it.

Your body needs a wide and diverse number of nutrients to heal the damage of Peyronie's disease.  There is no one nutrient that is more important than another in the healing process.  If you think this is not true, let us use the basic example of baking a cake.  A cake is made of just a few ingredients, like flour, milk, eggs, shortening,  baking powder, salt, etc.  And if I would ask you what is the very most important ingredient in a cake, you might answer that you simply must have flour in a cake and therefore that is the most important ingredient.  If that is true, then what would happen if you did not include the half teaspoon of salt or the tablespoon of baking powder in the recipe?  you would soon learn that not only do you have to use all ingredients to bake a cake, they had better be included in the exact amount required.  Baking a simple little cake demands that all ingredients be included at the right time and in the right proportion.  Can you image the process that is going on to correct Peyronie's disease?

Because of the complexity and great number of chemical processes involved in the healing process of Peyronies disease, we do not pretend to know exactly what your body might need that could be different than someone else.  To solve this problem we simply recommend that you include them all so that your body has the opportunity to use what it needs when it needs it.  Do not make the mistake to try to figure this process out so you can isolate one nutrient or chemical in particular.  

There is no special therapy or method of treatment that is used for a pivot (dent, ding, hinge or notch) deformity.  You are not treating the pivot with the PDI concept; you are treating your body so that it can heal the pivot, and your body needs a lot of help.  

The pivot or hinge deformity is very common.  TRH

Cost to continue the large or best Peyronie's treatment plan?

Dear Dr.Herazy I have a question. 

I purchased the video of the stretching of the PD from you and would like to purchase the large plan but this has also comes with the video. Can you sell it to me without the video and give me some credit?

Also for how long last the products for the treatment? How much is the additional monthly cost to continue the treatment for one year?? My Urologist put me on pentoxifylline and I taking it already for 2 month but I have seen no improvement. I would like to try your treatment. Thank you.  Please let me know.  Mr. Jetter


Greetings Mr. Jetter,

The gentle PDI Manual Penis Stretching CD is not the same video that is included in the large or medium plan; they are two different videos.  The large and medium Peyronie's treatment plans have the Massage & Exercise video that is different than the stretching video.   To follow the large or medium plan you would still need the Massage & Exercise video. 

When you order the large Peyronie's treatment plan you will never have to purchase the Genesen pointers or the Massage & Exercise video again,so they are a one-time expense.  Also, because you will use such as mall amount of PMD DMSO, Super CP Serum and Unique-E oil for each application, most men only order these three therapy items once every three months or so.  The other items (Vitamin E 400/400, Maxi-Gamma, MSM, Nattokinase, Fibrozym, etc.) are usually reordered every 4-6 weeks, or so.  I estimate that the average man spends about $95-$115 each month resupplying his large plan.  This is just a little more than the estimated $90-110 monthly cost to resupply the medium or better PD plan.  

Please let me know if I can help you during the course of your treatment.  TRH  


Questions about the Large (Best) Peyronie's treatment plan

Dr. Herazy,

I just ordered the BEST plan from your website. I know there's no way for you to know my exact condition, but do you recommend how many BEST plan I should purchase to stay aggressive. I'm concerned about the cost. I might only be able to purchase this one once.  Thank you for your help.


I think you misunderstand about the best or large Peyronie's disease treatment plan, and probably all the other plans. 

You only need to purchase the large or best plan once. After that first purchase you will only have to repurchase what you have used – not everything. 

You will never again have to purchase the Genesen pointers or the Massage & Exercise video.   You will likely only use the PMD DMSO, Super CP Serum and Unique-E oil once every three months or so.  The other items (Maxi-Gamma, MSM, Fibrozym, etc.) you will restock as you use them, about every 4-6 weeks.  I estimate that the average man spends about $95-$115 each month resupplying his large plan.  This is just a little more than the estimated $90-110 monthly cost to resupply the medium or better PD plan.  

Please let me know if I can help you during the course of your treatment.  TRH  

How about using ultrasound as Peyronie's treatment?

What are your thoughts on using ultrasound technology to treat minor Peyronies scaring?  Thanks


After reading a little about using ultrasound physiotherapy to treat Peyronie's disease I was not sure I was getting a full or accurate explanation about treatment results and effectiveness.   for this reason I contacted two of the largest manufacturers of ultrasound equipment for their opinions.   Neither could say it has been adequately tested or proven to work, and suggested that if I wanted to use it I should be the one to do the research for them. 

In view of this lack of interest and lack of clinical background using ultrasound for Peyronies, I have not pursued this subject further.  TRH

Would you like me to send you pictures of Peyronie's disease?

Dr. Herazy,

I am not concerned with sex right now and I have no pain, except I have depression from my Peyronie's disease.

It seems I have only two problems. 1) a failure in the integrity of the wall of my penis on the left side. This is at a specific point rather than so much at a curve, even though that is there also when it is more erect. My penis doubles over to the left because of the failure in the shaft wall when not erect. 2) When erect my penis wants to hug the trunk of my body towards the left side.

Would you like me to send you pictures?



it is very common for men with Peyronie's disease to feel depressed for a variety of reasons.   For many men this depression arises from the (false) idea there is little you can do to help yourself with your Peyronie's disease and that your life will never be the same.  I suggest you begin spending more time reading and studying the PDI website to overcome this feeling of helplessness that seems to come from the idea that no drug has been found to help PD.  You need to know that the body reverses and corrects PD in a fair number of cases, and for this reason your energy should be focused on increasing and supporting your natural ability to overcome your PD.   Once you understand there is a lot you can do to increase your odds for self-repair and learn more about Peyronie's disease you will feel less scared and depressed.   Once you begin to actually do something to improve your physical condition you will feel empowered and in control of you situation.

There is a great technique I use to help men with their depression, called EFT.   Please go to the PDI website to the page about using EFT for distressing emotional states.  I have worked with many PD men using this technique and the results are often rapid and gratifying. Contact me directly for an EFT session when you are ready to feel better. 

What you describe as a failure of the integrity of the wall of the wall of the penis on your left side is not at all uncommon for men with PD.  This is commonly called a ding, dent,, hinge or pivot.  It can be caused in one of two ways, or a combination of both.  The first is by the abnormal internal tissue tension or pulling from within the shaft by the fibrous PD scar located in the tunica albuginea.  The second is by leaky veins within the shaft that do not close completely because the presence of the PD scar.  You can think of the PD scar acting almost like someone putting his foot in the doorway and preventing door from closing.  In PD the scar prevents the veins from closing, thus no pressure is built up within the shaft.  Without trapping of blood in the shaft the needed hydraulic pressure never develops to create a completely strong erection.  This can happen in just one small area of the shaft that creates the small dent in the side of the penis.   

Your left leaning erection is probably related to both the scar and weak erection on the left side of the shaft. 

There is not any need to send pictures at this time, since PD treatment is not based on the distortion or curve of the shaft.  Treatment is guided by the size, shape, density and surface features of the PD scars that create the distortion.   You must develop an exact knowledge of these characteristics in order to help your PD.   Once you reduce your scars, you will improve the distortion pattern that  bothers you so much.  This physical improvement will greatly help your sense of depression. 

So, i suggest you get busy.  Please get started with a reasonable Peyronies treatment plan that you can find on the PDI website.   If you need help with this, please let me know.  TRH 

Can masturbation cause Peyronie's disease?

Dr. Herazy, I know you are a busy man, but if you can recommend something specifically for me, then I would greatly appreciate it to boost my confidence. I struggle with a very black depression from my Peyronie's. Here is my status: when not erect my penis is just fine/when about 30% erect I have the beginning of an hour glass shape/when about 70% erect the curve is on the left side/when fully erect it hangs to the left and has a curve on the left side. Also, question: can masturbation cause this to have happened? Thank You


If you are like most men, i believe the primary reason you are so depressed is that you do not realize how much you can actually do to help yourself recover from PD.  A large part of your emotional state is due to feeling helpless and depressed, and these start with not understanding Peyronie's disease.  Therefore, once you begin to learn more about the problem you will feel less scared and alone, as many men do with PD.  Once you begin to actually do something to improve your physical condition you will feel empowered and in control of you situation.

There are three things you can do right now to help yourself:
1.  Go to the PDI website to the page about using EFT for distressing emotional states.  I have worked with many PD men using this technique and the results are often rapid and gratifying. Contact me directly for an EFT session when you are ready to feel better. 
2.  Get my book, "Peyronie's Disease and Sex" to develop a better understanding of yourself and how women relate to your condition.  Men usually make their situation worse by assuming that women will automatically reject a man who has PD; this is often not the case when the man knows how to effectively manage his sexual problems.  This book can help you in this area.   
3.  Get started on the most aggressive Peyronies treatment plan you can sustain for a few months to hopefully begin to make positive changes in your physical condition.   As part of your PD education you should read, "Peyronie's Disease Handbook."  

Masturbation, by itself, will not cause injury that can lead to Peyronie's disease.  However, very rough or physically abusive masturbation practices can cause injury to the tunica albuginea that leads to PD.   All masturbation to be safe should be as gentle and well lubricated as sexual intercourse.   TRH 

Does this Peyronie's treatment really work?

Dr. Herazy, I am 43 years old with this condition. It sucks my erections are not as good as they used to be. I have also lost some of my length and width. The curve is upward,it has been 3 years now and I need some aggressive treatment that WORKS…REALLY WORKS….BOTTOM LINE DOES YOUR TREATMENT THERAPY WORK… AND CAN IT REALLY HELP ME. I am taking Peyreton at the moment and really questioning the herb. I do not feel its doing anything. If you can help please respond.


If you think about your basic question and what you are asking of me, I cannot respond either way.  No one can know ahead of time if any valid treatment will help any health condition.   You are asking for a guarantee, and I cannot do that for you; no one can do that for anything in life. 

No doctor can say that any blood pressure medicine will work, no surgeon can guarantee results, and you will note that not even the makers of aspirin can guarantee results.  Your request shows me you do not understand the Peyronie's treatment concept that is taught on this website. 

What I can tell you is that I receive anywhere from 10-12 emails and phone calls telling me of positive results and good success reducing the size, shape, density or surface features of the PD scar and subsequent improvement of penile curvature for every one email or phone call saying there is no progress under the PDI treatment. 

I can also tell you that the way you ask your question, "…can it really help me" is asked as though you want me to take the responsibility for your recovery and you are somehow not involved.  That is not the way this treatment works.  With the Peyronie's treatment concept you find on this website I offer ideas and suggestions to increase your ability to heal and repair the Peyronie scar, and you do the work.  You must take responsibility to learn, to understand and to apply these concepts to increase your ability to heal the PD scar; it works well for a high percent who work aggressively and diligently.  I have no way of knowing how you will apply what I teach, so I cannot guarantee any results for you.  

You bought your Peyreton because of the wild promises you read in their ad.  Not only did they guarantee you results from one or two bottles of their product, they made it sound as though the treatment is as easy as popping a few magical herbs and if it did not work they said you would get your money refunded to you.  Good luck with that one.  Over the years I have tried to communicate with the makers of Peyreton and I have yet to receive a single response from them.  I have offered to sell their product on my website if it is as good as they say, and they ignore my requests for information about their product and their company.  Many dozens of men have communicated with me over the years who say they got no help from Peyreton and were cheated on the promise of a refund from this company.  You should have known better.  I cannot make any promise to you because recovery from Peyronie's disease is never easy, it is never as rapid as anyone wants, and not everyone does it the right way.  You seem to want things easy and fast and guaranteed, and I cannot do that for you.  Your request for a guarantee suggests you do not understand the treatment concept that is taught on this website. 

if you want help getting over your PD I suggest that you spend some time reading about how this works for a lot of men.   If you really want to recover you will do this and you will contact me if you have questions.  Here is a good page to get started.  Just read the entire first page to get a better idea of how this Peyronie's treatment really works; you might even click on a few links that interest you. You will find that I will do all that I can to help you do the work of recovering from PD to the best of your ability.   TRH

How often and for how long do you recommend moist heat for the Peyronie's scars?

How often and for how long do you recommend moist heat for the Peyronies scars?   Thanks, Roger

Greetings Roger, 

Use moist heat prior to the topical or external therapy (DMSO application or especially manual stretching technique) .  For this reason it will be more efficient to perform these together as a group so you do not have to do it several times a day. 

However, it is probably not advisable to use moist heart immediately prior to Genesen therapy since it would easily throw off any level of tissue sensitivity and make it falsely look like EVERY place you touch with the pens are active – when this is not actually true.  You would wind up wasting your time by treating points that did not need it although they appeared to need it.

5-10 minutes is a good time range to apply the heat.  You are only attempting to draw blood to the area of the shaft, and it does not take that long to dilate the blood vessels for that purpose; you are not poaching meat.   TRH  

What is the correct way to apply penis traction for Peyronie's disease?

I really enjoyed viewing the CD video for the light manual penis stretching technique.   Good information that I can see will be helpful to correct my Peyronies 80 degree bend.  One question. Is the stretching technique a slow fluid motion that continues to increase or a static consistent stretch that is held for minutes at a time? Thanks. Darryl

Greetings Darryl,

Glad you like the stretching video.  It is a great technique that I think everyone should add to their plan.  Just do not make the mistake of thinking this is all you have to do to get rid of your PD. 

The way to safely and correctly stretch the penis is to keep the traction light and consistent.  Do not vary the light penile traction force once you develop the deep dull ache that is mentioned on the CD.   

Once the light traction force causes the familiar deep dull ache, it is held at the same static “force” until the dull ache disappears or boredom causes you to decide to stop.  There seems to be a natural tendency for a lot of men to slowly increase the traction force after a few minutes have passed.  Avoid this tendency and strive to consistently maintain the same contact vectors and level of touch.   You will know you have increased your force when you notice the dull ache stop; simply lightening the contact touch should cause the dull ache to return as the fascia again begins to yield.   TRH  

"Peyronie's Disease Handbook" is the real deal

Hi Dr. Herazy,

I am writing this message to tell everyone how much helpful information I found in your book "Peyronie's Disease Handbook." I resisted buying it because I thought I could figure out a lot of the treatment ideas on my own. When I kept on reading you mention about how important it is to use the size, shape, density and surface features of the PD scars to determine if my plan was actually working, I thought I also could figure that out by myself. And when I read what you said about diet and PD I thought you were just talking about losing weight. I was wrong about all that.

After wasting 8 months without making much progress at all I finally got your book. Your book is the real deal, no nonsense and has a load of useful information. It has made all the difference in the world and helped me finally get some measurable results, not only reducing my scars but regaining lost size and decreasing a bad 90 degree curvature.

Your book is worth every penny. It will help anyone who wants to get better results.

Thank you for all the work you.

E. Taylor
Dallas TX

How long to wait between using DMSO and intercourse?

Dr. Herazy,

Thank you for your time a moment ago when we spoke on the phone. If I may impose upon you for one last question: How long between application of DMSO to the shaft of the penis and sexual engagement should there be to avoid "sharing" the DMSO with your partner? Or, is this not something that one needs to be concerned with due to the benign nature of the substance?




Greetings Foster,

If you read on PDI website about DMSO you will learn that about 7-8 minutes after application for Peyronies disease treatment all DMSO is essentially gone from the surface of the skin and is being chemically taken deeper into the tissue; actually most is gone in 5 minutes or so.  Nonetheless, I suggest washing the shaft prior to intercourse because the penis shaft is covered with common skin as is the majority of the body, but inside the vagina is found a mucus membrane layer of tissue, similar to the inside of mouth or sinus passages.  This thin and delicate tissue might respond differently than the rest of the body – better safe than sorry.   TRH

Is hyperbaric treatment for my Peyronies worth doing?

I am considering hyperbaric treatment for my Peyronies. Is this something that would be worth the time and money?


Thank you for the interesting question.

Hyperbaric oxygen therapy or hyperbaric medicine is the medical use of oxygen when delivered to tissue a higher than normal atmospheric pressure.  To do this a flexible or rigid pressure chamber is used to deliver 100% oxygen (air typically has 21% oxygen to all or part of the body. 

Use of hyperbaric treatment is usually limited to those diseases that would benefit from greater than normal oxygen saturation in the tissue (stoke, air embolism, massive compression injury, bone marrow disease, etc.)  I do not see the possible association to Peyronie's disease treatment.   

Insurance reimbursement for this procedure would not be covered for Peyronie's disease, so the cost would have to be paid personally.  Since you did not say what the costs might be or time time involved in such treatment, i have no idea if it would be worth the time or money.

With so many various Peyronie's disease treatments around that have direct research behind them and a track record of success when used as PDI suggests, why would you want to experiment with this treatment?  

Will the PDI Manual Stretching Technique help a congenital penis curvature?

My penis has a bend in it which is approximately 45 degrees to the left and upward. Its been this way as long as I can remember, Im now 50 years old. I have had no problems with sex and have two children. My wife is starting to have some issues, so I want to know if its Peyronies or something that Im born with. Will the stretching techniques be good for me or is there something else I should try?


There are a few things I do not understand in your question.

It is not fair to either of us to ask if you have Peyronie's disease based on the information you have presented.  Besides, I really do not understand what you mean when you say you have had a 45° bend for as long as you can remember.  Are you saying you believe you were born that way or are you saying that you have had a curved penis for a very long time?  

When you say your wife is starting to have some issues, what do you mean?   Are you having sexual difficulty because of reduced ability to achieve an erection?   Difficulty making penetration?   Reduced size issues that often are a part of Peyronie's disease?  You will have to be more specific.

The PDI gentle Manual Penis Stretching Technique was first tested on men with PD, not congenital curvature issues.  However, I have now hard back from men with congenital curvatures who have reported positive responses; some small and some great.    TRH   

Report of reduced double Peyronie's curvature

Thanks for both the privacy of your followers and the knowledge of your experiences. It's been some time since I've both ordered the "Best" plan and have spoke with you.

I'm very pleased to say that my Peyronie's disease has improved to a point of encouragement. When this horrible thing of PD introduced it's self to me I had two points of curvature; one of approx 25* just below the head and a more severe, 90* curve at the base of shaft in which the 90* curve was to the left. Today after much work, when time is available, I'm very pleased to announce, the 25* curve below the head has completely corrected it's self with no sign of ever being scared and the 90* curve at the base has improved a little and is curved in an upward position when erect. This make relations more possible. Also the pinching pain of PD has all but go away. Therefore, I've ordered another plan today, together with both the positive experience and months of knowledge of dealing with this monster, "The PD I'm referring to" LOL,

I'm confident today more than ever that progress and healing will be in my future. Thank you so much for being the source of encouragement.


Thanks, LT

Greetings LT,

Thank you for the encouraging report of your success.   It is good to know you have reduced the double curve to some degree.  From the way you present your information it also appears that you have made this improvement while not being very faithful or aggressive with your therapy plan.

Please take this time as we begin the fall season to dedicate yourself to being more serious about doing what you know you should be doing.  If a partial effort got that kind of improvement, I can only assume you could have earned more progress by working more along the lines of our suggestions for your self-care. 

If you are having any questions or problems putting your plan together or following the plan you would like to use, please let me know and I will do my best to help you.  TRH 

What is the benefit of taking Neprinol rather than Nattokinase and Fibrozym?

Hello Dr. Herazy,

Thank you for the great site.

I am getting ready to place my first order with you and have a couple of questions:

1)  In your opinion what if any is the benefit of taking Neprinol over taking Nattokinase & Fibrozym. I understand your philosophy of overwhelming the problem but it seems like taking all 3 is overkill and from my limited understanding taking Nattokinase & Fibrozym sounds better than Neprinol?

2)  You do not mention the 15% Verapamil topical solution from PDLabs which seems to have had quite a few scientific studies done on it and the results seem to be very positive. Any thoughts on this would be greatly appreciated.

Thanks–I look forward to placing my order and getting started on a treatment plan.


Greetings Richard,

1)  The benefit of taking the single product, Neprinol, rather than the two products, Nattokinase and Fibrozym, is that the Neprinol is more concentrated and should result in taking fewer systemic enzyme pills per day while having a higher dosage intake.   In addition, Neprinol contains the additional enzymes of papain and bromelain.   The cost is higher for Neprinol, but considering the higher level of enzyme in the product, it is less expensive in the long term.   Yes, taking three different forms of a systemic enzyme might be more than is necessary, but for some men it does make a difference.  There is no way to anticipate how anyone will respond to their therapy plan, so I encourage everyone to experiment with different combinations of therapy products to determine how their scars will respond as you go through different combinations of products.

2)  Most every medical treatment for PD is the same – one or two positive studies and a larger list of negative studies about it.  The same with topical verapamil from PDLabs of Texas. The different studies mentioned by PDLabs of Texas are intriguing, but are contradicted by other similar studies of topical verapamil.  When i first developed PD in late 2001 or early 2002 and found the PDLabs website on the internet and read those studies I also was impressed with their conclusions.  for this reason I used their topical verapamil product for about six months, during which time my PD worsened considerably and I developed overwhelming side-effects that caused me to stop using the product.  At that time I realized I would have to look outside traditional medical treatment for helping my PD and I began to intensely investigate Alternative Medicine options; eventually I came upon the concept and and treatment protocol that developed into the Peyronie's Disease Institute.   Over the years I have discovered more controversy about their findings – but this is typical of any kind of treatment for PD.  It seems PD is always tangled in controversy and exceptions.   TRH 

What type of Peyronie's treatment should my husband try?

Dr. Herazy,

My husband has been struggling with accepting he has Peyronie’s disease.  The purchase of your book has really helped inform us about this disease. He is also a diabetic. What type of treatment should he try to help with his condition? He has not tried anything yet due to the fact of feeling like there is nothing that can be done or that will work. His case does not seem to be severe. We would appreciate any advice/support.
Thank you!


Your husband should start with the most aggressive therapy plan he is comfortable following so he will get the best results possible. If he is inclined to want to do everything possible to help himself, then perhaps he could consider using what is called the “Large (Best) Plan” for personal treatment. The “Medium (Better) Plan” is perhaps the most popular of the three plans. There is a “Small (Good) Plan” that is also well designed. These products and plans are found at Peyronie's treatment products.   All plans can be modified, by subtracting or adding, to suit your personal Peyronie’s disease treatment philosophy.

Or, you can design your own therapy plan using the information found on this website. You do not have to use any of these model plans, they are only examples – but they make sense and they have helped hundreds of men improve their Peyronies plaque and reduce the bent penis of Peyronie’s disease.

For a starting point for treatment, go to Peyronie’s treatment help starts here.

However, there is a larger issue, isn’t there? If he has taken the word of people who have played with using vitamin E for their Peyronies, or dabbled with taking Neprinol, and found that their results were not good, then he is in trouble. So many people love to get on the Peyronie’s disease forums and write, “I tried PABA (or something else), and it did not work. Nothing works!” I know from many hundreds of cases I have dealt with each year since 2002, that when someone writes something like that they have not gone about their treatment in the correct way. Using a single therapy is not the way to get results with PD. Their lack of good results is not surprising.

We are not conducting formal research, nor is it possible to collect meaningful research data based on the way that I have no way to monitor how people are following their plans. What I can tell you is that I receive 10-12 phone calls and emails telling me of Peyronie’s progress and improvement, for every one phone call and email I receive saying nothing is happening. That is a good rate of success. When I learn what these men who say they are not progressing are actually doing, it is easy to understand their lack of progress.    

If your husband is waiting for some Peyronie’s treatment that comes with a guarantee, then he is in for a long wait. No PD treatment works all the time or works well in every case.

It could be that he is in a state of depression and denial about having Peyronie’s disease. If you think that might be the case, please suggest to him that he calls so I can speak to him. I will be happy to do what I can to help him.   TRH

Any suggestions for using a DMSO "wrap"?

Hi Dr.Herazy my question is about using "wraps" im only using DMSO/Vitamin E/Castor oil wrap, im just curious what is the best way to leave a cloth/wrap that a guy uses to keep it in place, i tried using duct tape to keep the cloth on my penis it works but the thing is i can't keep it in one place, kinda loose on my penis so i feel like my penis isn't getting the complete benefit if i were to find a tighter wrap or bandage somewhere at or store… because i can't keep the cloth from sliding off, so i would like to know is there something i can buy like at Walmart or something im thinking of a way to keep the cloth adhere to the penis skin so i'll know the wrap with the 2 oils are getting into the plaque online some websites say to use a rubber band to keep it in place but that frightens me, so what is the best way and a place i can find a wrap that can adhere too the skin so it isn't so loose wrapped around the penis. It's so frustrating trying to use a DMSO wrap but can't keep it in place… any suggestions for people going this route?


Stop what you are doing for two reasons:

  • What you are doing is potentially dangerous – by applying prolonged compression to the penis with rubber bands or duct tape you cannot help but cut off blood circulation, and this is a good way to develop Peyronie's disease.  One of the proposed mechanisms of developing PD is by micro-reduction of blood circulation, and this is what you are doing.  Just like we are warned to release a tourniquet for a minute every ten minutes, you do not want to cut off blood circulation for too long to any part of the body.  Many men develop PD from using a "cock ring."  Your method of holding the wrap in place could easily do the same thing to you.
  • How you are using DMSO does not make sense – DMSO works in just a few minutes and does need to held in place for hours.  DMSO is a great PD therapy, but it must be used correctly and safely.   When you buy DMSO form this website you will be given complete instructions how to use it properly and without harm to you.  There is absolutely no reason to leave a "wrap" in place for hours on end, because nothing happens under that wrap after a very short time.  Your DMSO does its maximum work in the 1st seven minutes or so after you apply it to the skin, and after that not much happens. Using DMSO is not like sunbathing, when the longer you do it the more will happen.   If you feel a sensation of warmth, it is only because you have your shaft wrapped in a cloth that is covered by plastic.    

It is really amazing what dangerous and upside down thinking I see on the Peyronie's disease forums from people who promote ideas without knowing  what they are doing.  I think you were given some bad information.    

You are apparently, for some reason you did not explain, using a modification of the Thacker's formula.  If you intended to use the Thacker formula you were given false information about that, also.

There is a better way to use DMSO, just go to the PDI website to read how it should be done.   

Are male enhancement pills effective in helping Peyronie's diease?

I am using vitamin C, E, Scar-X, PABA, Fundamental Sulfur, Fibrozym, Nattokinase, Stimulin and Male Booster-X.  I have an hourglass curve at the base of my penis together with an upward bend. I am seeing some slight reduction in the deformity. My penis remains about an inch shorter than it was originally, Is there anything else I can do to regain the length. I tried the stretching exercises from your video with no result.  Are male enhancement pills effective?



There are many things to say about your email and how you are approaching your problem:

1. Listing your therapy products by name without telling me how many you are taking of each, and when you are taking them, is not helpful.  I need details of how you are using the therapy products you are taking.   I also need to know how long you have been using this plan.

2.  Stimulin and Male-X Booster are not intended to help Peyronie's disease.  I think you got the idea that sexual stimulant supplements can be used this way because many MDs prescribe Viagra for PD.  Viagra can be harmful to PD and even cause it; the sexual stimulants we suggest you use are mild enough that they will not harm you.   However, these two products will only increase sexual response (which is a good thing if you are having problems that way), but they do not help reduce the PD scar. 

3.  I am happy for you that you are seeing reduction of your deformity – congratulations.  But, that is not the way to go about monitoring your progress or determining if your therapy plan is working.  PD is all bout the Peyronie's scar.  Your deformity gets your attention and stresses you, and you want to get rid of your deformity, but it is the PD scar that is causing your deformity.  You must carefully monitor your scar to know how you are doing.  Your treatment plan is NOT determined by your deformity, but by the size, shape, density and surface features of your PD scar.  Please, you need to get "Peyronie's Disease Handbook" to learn how to do this; all of the important information about monitoring your scar is located in chapter 4 of that book. 

4. You have no way of knowing if the stretching exercise video did or did not help because you do not know the size, shape, density and surface qualities of your scar.  You are just guessing at this point if your stretching work was or was not helpful to you.  Besides, there is no way to isolate that one therapy did not help you while you are doing so many others.  All of your therapies work together to make changes in your overall condition.   You say your distortion is better, right?  How do you know the stretching exercises did not contribute to that progress?  Also, you need to tell me if you were able to feel the "deep dull ache" that is mentioned so often in the video while you were doing the penis stretches. 

5. Lastly, all your therapies are internal in nature.  This is a flaw of your plan.  You need to do some external therapies to round out your plan.  If you need help making that decision, let me know.  You cannot assist your recovery with a plan that is unbalanced between internal and external therapies.   

You cannot give me a few lines of vague information and expect me to help you.  Details please.    TRH   

Advice about penis spitting whitish yellow drops


I am having this problem and i am very conscious about my penis being disturbed. I have research a lot on your website and concluded that i am suffering from Peyronie's disease with slight left penile curvature without any constrictive ring or hourglass. 

My penis is spitting whitish yellow drops whether i am awake or sleeping and I am helpless to do anything.  I started throwing all my underpants and pajamas.   I used to masturbate a lot before 3 to 4 months, and used to grab my dick head to stop wasting the sperm, until one day it hurt me very bad.  But ignoring that day i slept  and after a couple of days i started feeling heavy pain that I used to hold my piss for a whole day or even 2 sometimes getting afraid of the pain.  Then gradually it decreased, and now again i am feeling pain with every piss.   My penis is curved slightly left and spitting drops very often.  I have postponed my wedding due to this, and really is very dishearted of the situation.

Please help me out.  I will always pray for you and your family in good or bad times.  A detailed and prompt answer would be highly appreciated

Best regards,  Umair


Greetings Umair,

Based on your description it is possible that you injured your urethra by your practice of masturbating but pressing on the head of the penis to prevent complete ejaculation.  I think it is not likely you have Peyronie's disease, even though you do have a penile curvature.

I strongly encourage you to go to your local medical doctor and explain your problem to him for prompt medical attention.  

Good luck to you.  TRH

Is there a treatment for my hypospadias?

i don't think i have this condition, but what is the matter with me is, i never was circumcised and i have a false opening. i urinated from beneath the head of the penis through a very tiny opening. after all these years, i can't even ejaculate  anymore. Is there a treatment for my problem?



As you are probably aware, you were born with a condition called hypospadias.  This is a birth defect that affects 400-500 births in which the opening of the urethra (pee hole) is not in the normal location.  When hypospadias occurs in boys, the opening is located on the underside of the penis, and when it occurs in girls the opening is into the vagina.  Surgery is most often elected to be performed before the child reaches puberty. 

There is no association of hypospadias and Peyronie's disease.  

I suggest you find the most competent and skilled surgeon specializing in genital reconstructive surgery for consultation.  

Good luck to you.  TRH  

What about using Kegel exercise as a Peyronie's treatment?

2 very simple short questions do kegels exercises help peyronies i read it will or may because it's said to be a exercise that women used but it can be used in men and online says it can force more blood into the penis and help with the healing process. The other i have on my mind is i read W What does it mean to "Break Up Scar Tissue" I was reading about castor oil and they said it "breaks up" internal/external scar tissue and breaks them up? Is it different than "reducing" Could you clear up this definition? Thanks, and hope this wasn't too much to ask, but i just didn't want to forget the other question so i just put them both here in one, thanks again Dr. Herazy.


Yes, spend a of of time in our video. "Massage and Exercise" for Peyronie's disease to give you specific measures to assure you do Kegel exercises correctly for PD.   I have advocated Kegels for PD for many years, and used them as part of the Peyronie's disease treatment protocol when I got over it. 

You will have ask those people who use these terms – breaking up and reducing scar tissue – what they mean when they use them.  To me it sounds like careless use of words.   TRH

What are the chances my Peyronies will stabalize soon?

i am a healthy 50 yr old who has been diagnosed with Peyronie's disease about 14 months ago.  I've had a dent about 1 inch from the base approx.2 inches long during erection.  I thought it was stabilizing but seems to be getting slightly worse, moving towards the head.  I now think I'm starting to get some ED.  No treatment except vitamin E.  Starting to stress,what are your suggestions on treatment?   What are the chances this will stabilize soon?  Should i expect this to get worse?  Are the ED drugs (Viagra) a good idea to use?


You are asking several questions, most of which are answered many places within the PDI website.  I suggest that if you wish to learn more about PD you spend a little time reading what is here for you.  I will go through the questions and points you raise in order.

What looks like movement of the indentations is more likely the result of changes in the internal scar tissue, causing different patterns of pull on the tunica albuginea and layers of fascia within the shaft.  There is a wide variation of development of Peyronies, so be aware that your particular situation might be different from others you read about.  for many men these small but accumulative changes of the PD plaque or scar causes deformity changes over a period of many years.

There are two probable ways you could be experiencing ED at this point:  Physical – from the growth or contraction the PD scar material causing the internal valves of the veins of the shaft to remain open, thus preventing development of internal hydraulic pressure that creates an erection.  Sometimes this is a widespread problem affecting the entire shaft, and sometimes a local problem causing dents or bottleneck deformities.  Emotional – you are, as most men feel, angry, confused, scared, and/or embarrassed about what is happening to you.  The emotions have a great impact on the development of the erect state.

Using vitamin E by itself is almost no treatment   Vitamin E as a Peyronie's treatment is a great therapy, very essential, but it must be combined with other therapies to get the right kind of tissue response you are looking for.  

Treatment is the most thoroughly discussed subject on this website.  See Introduction to Alternative Medicine treatment of Peyronie's Disease, and Guide for Peyronie's Disease Treatment, and many others.

The PDE-5 category of drugs (Viagra, Levitra, and Cialis) can cause problems due to excessive erection development, resulting in over-inflation and possible tearing of internal tissues of the shaft.   See Peyronie's Disease Plaque, Viagra, Cialis, Levitra and Blood Supply  and  Peyronie's Disease Treatment and Viagra, Levitra and Cialis and many others.

Far better to learn about Alternative Medicine treatment of Peyronie's disease, take control of your situation, stop feeling so helpless and reduce your stressful state.  If you have specific questions about treatment please let me know.     TRH   

Is it really possible that Peyronie's disease completely disappears?


Is it really possible that Peyronie's disease actually completely disappears?

One often-quoted study says that 13% of cases improve spontaneously after one year. This, however, includes very small curvature or plaque reduction. However, I have not heard of one single reliable and medically documented story of complete remission. It seems that even if some treatments appear to be effective in reducing or even dissolving the plaque, the tunica can never regain its original elasticity.

Can you give us your thoughts about this please.

Best regards,



Greetings Leo, 

Thank you for the excellent question.

How often, and to what degree, Peyronie's disease spontaneously recovers is such an interesting and important PD topic that I wrote,  Spontaneous Remission and Natural Cure of Peyronie's Disease.    You might consider reading this also for additional ideas.

Anyone who has looked for help with Peyronie's disease knows why it has been called the bastard-child of medical practice.  No one should be surprised it has never been the subject of investigation to determine the frequency or degree of spontaneous recovery or natural healing.  I could not find any information about what criteria is used to determine a complete response to treatment or a spontaneous remission of Peyronie's disease.  For example, when all outward signs of cancer disappear after treatment, this is called a "complete remission" or a "complete response."   These terms do not necessarily suggest the cancer has been cured.  It only means the cancer cannot be detected in a way that it was previously used to identify it.  If after treatment the cancer is still present but in a reduced capacity to incapacitate the patient or of a reduced size, it is called a "partial remission."  In regard to Peyronie's disease these concepts might also apply, but this has not been worked out clinically for PD.  For this reason, the words we use (remission, recovery, response, cure, improvement, complete, partial) are subject to controversy because they have not been defined in relation to Peyronie's disease.  

Thus, there is room for interpretation when you ask if Peyronie's disease ever "completely disappears."   A consensus would have to determine if a practical (functional) or anatomical (structural) definition of recovery was to be used for Peyronie's disease.  Previously I have written, "the average man would not care at all that he had Peyronie's disease if it did not cause a penile distortion that denies him from having sexual intercourse.  If the Peyronie's lump did not interrupt sex activity, the problem would be essentially ignored." 

While i understand the thought and motive behind asking about a study of spontaneous remission of Peyronie's disease, I believe it is unlikely for the pharmaceutical or medical industries to actually spend money to research if this problem goes away on its own.  Their focus is far more likely to be directed toward drug creation or surgical advancements.  In preparation for writing this reply I Googled "spontaneous remission cancer" and "spontaneous recovery flu" and could not find any medical studies for those searches.  That this information is not available should not be interpreted that these things do not happen, but only that no one yet has taken the time, effort and money or has a vested interest to study these topics.   

For a majority of men, from a practical or functional standpoint, restoring sexual function would define "complete recovery" if this occurred as a result of direct treatment, or "spontaneous remission" if this occurred without treatment, regardless if the Peyronie's plaque persisted or the tunica albuginea was less elastic.  To underscore this prevailing and practical attitude that men take about their Peyronie's condition, I have communicated with many men who have told be that they like having Peyronie's disease because their particular direction and degree of penile curvature increased the sexual pleasure of their partner and thus they saw themselves as better lovers. Their interest in correcting their Peyronie's disease was equally practical and sexually motivated:  they were concerned that if the curvature worsened, they would not be able to engage in intercourse.  Conversely, from a clinical or anatomical standpoint, restoring previous physical normalcy (external appearance of the shaft, elimination of the internal fibrous plaque, complete elasticity of the tunica albuginea), would define "complete recovery" if this occurred as a result of direct treatment, or "spontaneous remission" if this occurred without treatment.  Without these terms being defined it is difficult to communicate accurately.

Yes, I am aware of that study reporting 13% of cases improve spontaneously; others reports suggest up to 50% of Peyronie's disease cases simply go away without treatment.  This variation in numbers is probably due to a different set of criteria for determining what degree of improvement constitutes a real improvement  or recovery; this is discussed in the 3rd paragraph. Given the nature of the problem It is easy to understand why there is still controversy and revision (usually upward) of the reported rate of occurrence of PD in the general population, to say nothing of the rate of spontaneous remission for the problem. 

When I developed Peyronie's disease I struggled frantically looking for a way out of the Peyronie's nightmare.  After reading reports of 20-50% spontaneous recovery from PD my thoughts turned in a more positive and productive direction.  The pivotal insight that occurred to me was:  "If 50% of men heal their own PD, then the body has a cure – even if the MDs do not.   All I have to do is increase my immune response to this PD scar in whatever way makes sense to me, and I believe I might be able to heal my problem like those lucky men who spontaneously correct their own problem.  Now I am in control."  Before that I held the common negative and hopeless victim mentality displayed on many of the Peyronie's forums. This little bit of information so encouraged me and uplifted my thinking, that I eventually developed the treatment protocol that enabled my body to heal my PD problem.  This same protocol (now improved in several significant ways) has since been used many hundreds of times by men who learned about it on this PDI website.

From my experience in working with men since 2002 I have used the informal, uncommitted, and long-distance format of the internet, emails and telephone calls.  Since I am not conducting formal research, I have no way to control, monitor or verify how anyone is conducting his PD therapy plan.  Men do what they want to do.  I can only offer suggestions and hope my message gets through.  Not only does everyone seem to create a slightly different therapy plan, but each man goes about using his plan in a different way.  The non-uniform and irregular application of the ideas you see on the PDI website makes it difficult to evaluate effectiveness or degree of improvement achieved.   Not only that, men are notoriously bad communicators about this aspect of their private life.  Once Peyronie's disease is eliminated from a man's life he quickly disengages from the problem and happily returns to his previous life, rarely contacting anyone about his success.  They gladly try to forget about the condition that so humiliated them and nearly ruined their lives.  Men are reluctant to discuss or report on the stigma of diminished size, erectile dysfunction and disfigurement associated with Peyronie's disease.  For these reasons the number of men who experience spontaneous improvement of their PD will always be much more speculative than even the number of men who have PD, which is wracked by speculation for the same reasons.      

You are correct, there are no formal medical studies of complete Peyronie's remission.   But what of those published medical statistics reporting 13-50% of cases that get well without treatment or outside intervention.  Is that not more than the medical acknowledgment or the single story of complete remission you asked for?  Further, what of the hundreds of urologists and family doctors each day around the world who advise their newly diagnosed Peyronie's patients to "come back in six months to see it it goes away"?  Aren't each of these MDs implicitly saying that from their experience they see a sufficient percent of PD cases clear up on their own, thus justifying the standard wait-and-see strategy they all use?  "Wait-and-see-back-in-6-months" is part of the standard medical protocol and must exist for some reason; do you think that spontaneous remissions happen often enough to build a treatment protocol around it?  I do.

I offer a simple speculation about the condition of the tunica albuginea after favorable Alternative Medicine treatment, because I do not know.  The body eliminates to the best of its ability what it does not need.   I have a scar on my knee from a childhood injury.  Over the years it has slowly faded and now is barely visible.  I assume that if there is no useful purpose for the PD scar within the tunica albuginea, the body will pick up the collagen fibers over time.  This might not be a fast process like the body removing the cells of inflammation, but it should at least in theory happen if only because the body is designed to eliminate foreign matter.  Along that line of thought, I am a retired chiropractor with a highly refined sense of touch developed over 42 years of practice.  When I report that I cannot find any evidence of my previous gang of PD scars, you can believe that they are either gone or so dramatically diminished in size.  Of course, this is ultimately speculation because surgery would be required to verify the actual state of my tunica.       

Lastly, it is difficult to know how to label my particular improvement of Peyronie's disease or the experiences of those men with whom I have worked.  They no longer come to the PDI site for treatment information because they are apparently satisfied with their previous Peyronie's problem after following their version of PDI therapy protocol.  I do not know if I can say my body eliminated or cured my Peyronie's disease, or not. I do not know if I can say I had a "complete remission" or a "partial remission" because those terms have not been defined clinically. 

All I know for a fact is that back in 2002 when I was at my worst, I could easily describe 4-5 different plaque primarily on the left and dorsal aspect of the shaft.  My primary distortion was a combination 35 degree curve to the left, a ten degree curve upward, with a counterclockwise rotation.  I say primary distortion because twice while I had this combination curve and twist, it was replaced for a few weeks by a severe bottle-neck deformity that made me sick to look at.   After following an aggressive and faithful PD therapy plan that I devised over many months, all of that went away.  I was able to monitor the slow and gradual reduction of the size, shape, density and surface features of each of those 4-5 plaque.  As I observed them slowly fragment and disappear, my distortions disappeared and my lost length and girth returned.  Today I cannot find any PD plaque and my shaft is straight.   I have worked with many men who have reported various stories along that same basic outlineOf course, some men respond better to Alternative Medicine therapy than others; not all respond well, and some do not get any improvement at all.  When I learn of men who are not making improvement I can usually trace it back to a small and non-aggressive application of the PDI therapy concepts that is revealed by meager and irregular purchase of therapies. Conversely, those men who report better results ask more questions, follow a more faithful and aggressive plan of action, and overall seem to be more focused and serious about their eventual recovery.       

Back to your original question, "Is it really possible that Peyronie's disease actually completely disappears?"   By that question I take it that you mean, "Is it possible that the tunica albuginea returns to a completely normal state after what you call a self-repair, self-healing or spontaneous remission?"  To that question l answer that I do not know.  I must assume that in order for my curvature pattern to improve, for my scars to be undetectable, for my lost length and girth to have been returned, that some favorable and demonstrable tissue change must have occurred within substance of my tunica.  This in turn should have caused the tunica to become more elastic than when it supported the nasty Peyronie's plaque.  Speculation, for sure, but logical.

For me, and I believe for the men who come to the PDI website looking for some straight information about what they can do to help themselves get well, I wish to say we do not care if the tunica albuginea completely returns to normal or not.   I am satisfied when a man tells me he cannot find his PD scar any longer; that he can have intercourse for the first time in many years; or that his penis is now straight.  At this time I am more interested in learning how to more effectively help the men who have Peyronie's disease so they can more quickly and efficiently eliminate their problem, than I am in splitting hairs while defining the words cure, healing, recovery and remission.

Again, thanks for the great question that gave me the stimulus to put a few thoughts on the internet that were not there previously.

Good luck to you and I trust that you are successful in dealing with whatever prompted your interest in this subject.  If you have interest in learning about Alternative Medicine Peyronie's disease treatment, please let me know.    TRH

What would you suggest I do to treat my Peyronies at this point?


I am the same man who is 73 years old now. who developed PD when I was 57. You responded to my recent question if there is anything I can do for myself or if after 16 years of having PD the time for treatment has passed.  

I took Potaba (24 tabs a day for 2 years) when I was first got my PD.  What would you suggest I do at this point?  If you need more information, please contact me at the above email address.

Thanks, Jim Young 


Greetings Jim,

First, please reread a part of the response I gave you yesterday.  I have already given you that exact information what you should do next when I wrote:

            "I think the healthiest and fairest way for you to approach your decision if you should
            attempt treatment is to first learn what is involved in the Alternative Medicine approach
            to recovery from Peyronie's disease.  Then decide what is a reasonable length of time you
            should be willing to devote to an aggressive and faithful program of care; maybe 4-6
            months.   If it all makes sense to you, then begin care with the attitude that you will do
            your very best.  

            "A good place to begin learning about this unique PD treatment is start Peyronie's treatment.  
            Let me know if I can assist you in any way."

I trust you went to that link and read carefully everything that is there for you.   

Already I have told you what I think you should do:  read and learn about how this PDI method of Peyronie's treatment works, then decide if it makes sense to you and if you can make the commitment to do it well. This is a fairly straightforward answer that should have been enough to get you going in the right direction.

But, I believe I understand your problem knowing what to do next. Your follow-up question, a common one, is basically asking me to take over for you to decide what you should do.  I cannot do that.  You are asking me to be your doctor, and I cannot do that from a 1,000 miles away without having examined you.  You are not my patient.  Actually, I would be a fool to make that kind of decision for you under these circumstances, and you would be a fool to listen to me. 

Almost everyone who first comes to the PDI website is in a common frame of mind in which you feel hesitant to take more control in the decision making process about your physical condition.  In this modern era in advanced countries a patient goes to the doctor, gives answers to a few questions and the doctor tells the patient what to do.  The patient often is given very little time and very little information about the problem or its treatment.  This is different.  In this situation I try to help you learn how to do this process of increasing the ability of your immune system to eliminate the PD scar, and you making all important decisions.    

Sixteen years ago you learned what happened when you received the standard medical treatment for Peyronie's disease.  The doctor decided you should take POTABA for two years –  that probably caused a lot of abdominal pain and digestive problems –  and nothing happened.  I will assume the doctor did not tell you much about your problem or treatment, and they were all rather fast office calls. You just did what you were told and that was about it.  This is different.  You have to be in control because I cannot.  You learn as much as you can about the process of using Alternative Medicine for your Peyronies problem.  When you run into a problem or have a question, you can return to the PDI website to get an answer. 

As a further suggestion, for you to accept or not accept, if you are still having a difficult time deciding on how to get started, you might consider looking at the three model Peyronie's treatment plans at the top of store front.  These are examples of what a good treatment plan looks like.  They are balanced and they fit into different price ranges.  Each of them can be modified by adding or subtracting the ingredients if you want to do that.  Your decision which you should use, if any. 

You will be pleasantly surprised, if you decide to use Alternative Medicine to assist your healing process, how much detailed educational information is included with each order PDI sends to you.  Written instructions are included with each order, providing information about the correct use of whatever you purchase from PDI and Online Natural Healthcare LLC.   We attempt to provide all the information you need to make a good decision for yourself.        TRH

Do you have any natural treatment to replace Flomax?

I am using your program of PDI.I am using flomax for prostate enlargement. Do you have any natural treatment to replace the flomax which destroyed my sex life.I will send any fees in advance. I am grateful for your help. Thank you Sami Shenouda

Greetings Sami,

Flomax is well known for its long list of unpleasant side effects.  Many men decide they are worse than the symptoms of prostate enlargement.   You should talk to your doctor about the side effects of Flomax and discuss alternatives with him before changing your prescription drug intake.

Because Peyronie’s disease commonly occurs in men who are in the same age group in which BPH (benign prostate hypertrophy) occurs, I am often asked about working with BPH at the same time as PD.  For this reason PDI lists two very good herbal products, BioProstate and Prostate Supreme.  I have taken Prostate Supreme daily for many years. You can find them by going to the PDI store front.

Please talk to your doctor before making any change with your prescription drugs.   TRH

Can I treat Peyronie's disease after 16 years?

I have had PD since I was 57. I am now 73. Is there anything I can do at this point or has the time for treatment passed?


Yes, there is a lot you can do and this might make you feel good about yourself for the first time in a long while.

From my experience in working with men who have Peyronie's disease, most stop looking for information and help after just a year or two.  These men are defeated by the negativity they encounter on most Peyronie's forums.  The great majority of men who contact PDI for assistance have had their problem for less than five years.  Occasionally someone will contact me who has had PD for 10 years.  The longest standing case I have worked with previously was 12 years old.  Your 16 year old case of PD puts you in a special category.

While working with these men whose problem is older than average, I have always been impressed with the ability of the Peyronie's plaque or scar to still respond favorably.   As with those whose PD is still in the common five-year range, the response to Alternative Medicine treatment still seems to be in direct proportion to the aggressiveness and faithfulness of care provided. 

There is no way for me to predict or anticipate how anyone will respond to non-drug and non-surgical Peyronie's treatment.  I think the healthiest and fairest way for you to approach your decision if you should attempt treatment is to first learn what is involved in the Alternative Medicine approach to recovery from Peyronie's disease.  Then decide what is a reasonable length of time you should be willing to devote to an aggressive and faithful program of care; maybe 4-6 months.  If it all makes sense to you, then begin care with the attitude that you will do your very best.  

After so long living with this lousy problem, I commend you for not being beat down by all the negativity and hopelessness that surrounds Peyronie's disease. 

A good place to begin learning about this unique PD treatment is start Peyronie's treatment.   Let me know if I can assist you in any way.  TRH

Is it possible for the Peyronie's scar to be that small?


Please allow me to explain what's going on with me and advise on if I should proceed with treatment.

I've been having painful erections for 6 months now. It was an immediate progression and the pain has not subsided at all. It begins as i'm getting erect and the pain is quite substantial for the first few minutes after which it subsides quite a bit. There is additional pain when I squeeze/flex it…like you would if you tried to stop peeing midstream. This leads me to believe that it's something with the blood stream. The range of motion is extremely limited and is very painful whenever it's moved too much. I'm now at the point where i'm not getting as hard as I used too and part of it is a mental block because I know it's going to hurt. I haven't been able to achieve a full hard erection on my own for a couple months now.

I've gone to my general practitioner and a urologist and left without a resolution. I've searched tirelessly for an answer and peyronie's is the only thing that even remotely fits my symptoms. I've been checked for STD's, did a urine and blood sample, and everything checked out. My hesitancy with the diagnosis is I have no deformity with my penis and I'm unsure of any plaque buildup. There is a very small hardness in the center of my penis when flaccid that is a little painful when I press it. I would relate it to the size of the tip of a ballpoint pen. But it's not rock hard because it still feels somewhat squeezeable. Is it possible for it to be that small?

Could I be in the beginning stages and still feel this much pain? Is it safe for me to treat myself as if I have it to see if works? I keep reading about where this could lead and it's quite scary. My experience with traditional doctors has been very frustrating and expensive. The urologist didn't even consider peyronie's until i mentioned it but both doctors checked for it and neither felt any buildup. He said to take some vitamin E and that should fix it. I've been taking an extensive amount for 2 months now and nothing has changed.

'm 32 years old and in great health with an active sex life. I'm extremely concerned with these issues and i feel completely lost in finding a solution…please help.



Your story creates a picture of some poor care. 

First some basics about a few statements or observations made about Peyronie's disease in general and your situation in particular.  I will just respond back to what you have mentioned:

  1. Peyronie's symptoms can be rather variable from one man to the next.  You are having more pain, and more consistent pain, than most men experience with PD, but that does not mean it is not PD.   Some men have no pain with their PD condition.  
  2. Not having the advantage of having examined you, I can only speculate about the source of your pain.  My educated guess is that it is not coming from a blood vessel but from the PD scar pressing on the tunica albuginea and another layer of penile tissue called Buck's fascia which is rick in pain fibers.  If you had constant pain, or if your pain coincided with your heart beat I would then consider it could be related to a blood vessel.  Both of these tissues I mentioned could be irritated and stimulated enough to generate pain when being squeezed.
  3. You say you left two medical offices without resolution, meaning they did not come up with the diagnosis of PD.  What did they speculate could be your problem.   Did they just leave you hanging with no ideas, no follow up?  So it is you who has come to this possible conclusion of Peyronie's disease on your own after doing some reading on the internet.  The fact that you mention your blood work was negative makes a case for not having a serious or life threatening problem going on, my speculation is that this supports PD as a possible diagnosis.  Personally, I have to suggest that you go to a third doctor to see if you can find a doctor who will take your problem more seriously than the first two.
  4. Peyronie's disease does not always cause a deformity, especially as early i the problem as you could be at six months duration.  Do not expect all cases of PD to demonstrate deformity, or to have it so soon; some do, and some do not.
  5. The small area of hardness you feel when flaccid that is the size of a ballpoint pen tip, could be your PD scar.  Did you show the MDs this area?  What was their response?  Many times a rushed medical examination will miss a small lesion like this.  You should have shown it to both of them, and demanded more time and attention to your problem. 
  6. Not all PD scars are rock hard. Some are so soft as to be almost undetectable.  This is why so many are missed on examination.
  7. Yes, you could have this much pain in the early stages of your problem.   It is amazing to me that you could have seen two doctors about your PD and not have been given this basic information. 
  8. Considering you were told you have Peyronie's and they only extended vitamin E as a treatment option, it is up to you to determine how you wish to proceed.  It is also up to you to determine the safety and appropriateness of undergoing a therapeutic trial of care for Peyronie's disease using Alternative Medicine  I cannot make that judgment; you have to take that responsibility for yourself.   I have had many men take this approach and were glad that they did.
  9. The PDI website is full of information for you to read and learn.   I suggest that you go the PDI and look at this link to learn how to start Peyronie's treatment if that is what you decide to do.  

Good luck to you and let me know if I can answer any questions as you look into this further.    TRH

Could Peyronie treatment plans still possibly help my congenital curvature?

I have been searching for a possible remedy for my penis. I have a slight downward curve, I believe it is congenital because I've always had it, and there is no scarring underneath my shaft or pain. Could your treatment plans still possibly help my congenital curvature? even if i don't have Peyronies? PLEASE HELP, this is causing me so much emotional discomfort doc!


The PDI treatment plans are specific for Peyronie's disease.  However, I have been told by men who have congenital penile curvature that they used the information and technique from the PDI Manual Penis Stretching CD with great benefit.  I suggest you review that information to see if it makes sense to you and proceed accordingly. 

Additionally, since most congenital curves tend to be gradual and mild, I suggest that you could be making more of your lack of total straightness than it deserves.  Perhaps your values and sense of self-esteem exaggerate your emotional response to your variation.  It might be helpful for you to read "Peyronie's Disease and Sex" to get some insight into the way you are feeling about yourself.  TRH

Is it OK to eat only the white part of the egg?

Hi Dr. Herazy, 

I have recently been diagnosed with Peyronies and I have bought your book and just started the medium plan.

I have always been interested in nutrition and thought that my diet was OK but now I realize that I actually need to change what I eat a lot. I am just about to change my diet based on the recommendations you have laid out in your book. However I have a few questions about the diet:

I have noted that eggs and diary products are on the avoid list. Is it OK to eat only the white part of the egg?

At breakfast I often eat porridge made of oat flakes and water together with cottage cheese, fruits and milk. Is it OK to still eat cottage cheese if it is low in fat if I cut out the milk?

The reason for these questions is that I try to understand what is not good with eggs and milk. I assume it is because of the yellow part of the egg with cholesterol and because of the fat in the milk. However there may be other factors so I would be most grateful if you could pls let me know if I can still eat cottage cheese and the white part of the egg. I want to have an aggressive approach to cure my Peyronies disease and I am ready to change my diet, do various exercises and follow my supplement plan as long as it takes.

Pls give a comment also on my plan as follows:

Daily I will take the following:

vitamin e factor 400/400 – 2 pills per day
vitamin e factor maxi-gamma – 1 pill per day
vitamin c natural c – 1 pill per day
vitamin c ascorbplex 1000 – 1 pill per day
MSM 10g per day – 5g in the morning and 5g in the evening
Fibrozym – 2 pills x 3 times a day
nattokinase – 2 pills x 2 times a day
Scar x – 3 times a day
DMSO + cupper + Unique E oil at least once a day after shower

Added to my plan:
Paba – 1 pill x 2 times a day
OmegaT – 1 pill per day
Quercetin Bromelain Complex – 1 pill twice a day
Acetyl L-Carnitine – 1 pill twice a day

Would be most grateful for any feedback. Thank you so much for having created this service. Rik

Greetings Rik,

Thank you for your diet questions and the detailed report on how you are approaching your Peyronie's therapy plan.  

You have obviously taken to heart the dietary recommendations found in chapter 5 my book, “Peyronie’s Disease Handbook”   In this chapter is discussed the dietary aspects of treating PD in which I present the idea that certain foods and styles of eating can contribute to PD.  

In that same chapter of the book that talks about different dietary issues, at the very beginning I say that most of the dietary suggestions are based on ancient Oriental concepts that are used in the practice of acupuncture and yin/yang.  I go on to say that it would require an explanation that could run for several books to completely and thoroughly explain these concepts.  You are asking a simple and direct question that from a Western standpoint should have a simple and direct answer – that makes sense.  But the answer is not so simple or direct – it is very complex without a good understanding of traditional yin/yang concepts. 

The chapter that you are referring to is very clear on this point,  that this list represents Eastern thinking, not Western thinking.   Many of the food items mentioned in the list to avoid are really good nutritional foods – from a Western standpoint.  However, these foods are not considered from a Western perspective but from an Eastern perspective.  This is where the idea of avoiding cheese, eggs and banana comes from; not from a nutritional standpoint but from an energetic standpoint.  It is not related to fat or cholesterol as you suggest, but from the Eastern concepts of energy creation, movement and stagnation of that same energy.  

The closer you follow these dietary guidelines, even it does not make sense to your Western thinking, I believe you will see your results follow. You can decide to eat all or part of the egg hte

If you really want to know more I suggest that you simply get several acupuncture text books and study the subject thoroughly.

Your PD therapy plan is balanced and is a reasonable start in Peyronie's treatment.  Congratulations.  There is nothing I can see that is essentially wrong with it.  As you are using your plan right now, it could help take you all the way to reversal of your PD problem, or it could be insufficient to help you.  There is no way to know if a plan is correct for you by looking at it.  You must put it into action and see what it does after 10-14 days to change or reverse the size, shape, density of your scar that is always the ultimate determinant if your plan is correct or not. 

If following this plan causes changes in your scar, then continue with your plan until your scar is either gone or stops responding to it.

If following this plan causes no changes in your scar, then modify it in some way and again re-evaluate your scar in 10-14 days to see if your scar changes in some desirable way.   If you need help in determining what to change in your plan, please provide a detailed description of your scar as you learned to do in chapter 4 of that same book so I might understand what is going on with you a bit better and I will offer you some suggestions to consider.

Follow your plan faithfully and aggressively and let me know if I can help you in any way.  TRH 

Will either of these treatments also help with energy?

Will either of these treatments also help with energy? I am  thinking of ordering the Best Plan because of the curve.  My erectile dysfunction is really bad without taking a pill.


You did not mention any Peyronie's treatment in particular to know how to answer your first question. Since all metabolic processes in the body require the use of vitamins and minerals as found in all of the PDI therapy products I am sure you could say that using any of our plans would be helpful for energy conversion in the body.

The PDI Best plan is becoming our most popular of the three because it is so broadly based and aggressive in design.  It does not cost much more than the PDI Medium plan to resupply every month since the greater cost of the PDI Large plan is due to the one-time expense of the Genesen Acutouch therapy pens.  

Many men with PDI fall into the trap of erectile dysfunction since there are so many emotional issues related to dealing with PD.  Additionally, the Peyronie's plaque is notorious for disturbing the ability of the penile veins to close, and thus prevent blood being trapped in the penis as it should to create an erection.  

Let me know if I can help you in any way with your Peyronie's therapy.  TRH                                                                                   

Start with the large plan and other Peyronie therapy later?

Dear Dr Herazy,

I have had PD for about 9 months and I am about to start the full PDI therapy programme, based on the advice you give in your book “Peyronie’s Disease Handbook”.  I received the PD Treatment Plan-Large, but I now notice that some of the recommended supplements were not included: Acetyl-L-carnitine, PABA, Neprinol, etc.

Can I assume that you recommend getting started with those supplements in the Large Plan and add others later?

Thanks Peter (based in France)


Greetings Peter,

The large Peyronies treatment plan does not include all available therapy items that could be used.  There are 12 different forms of therapy contained within the large plan, and as you correctly point out there are several that are not included. There are several reasons the large plan is limited to these particular therapies:

1.  Additional therapies might not be needed beyond what is in the large plan.  Many men do quite well on the large plan just as it is, and do not need to spend more time, energy and money using more therapies than these current 12.

2.  The wide variety of therapies in the existing large plan allow for enough opportunity to experiment with treatment dosage to take several months of active work.  If the large plan provides insufficient, then there are additional therapies to include at a later time for further experimentation.

3.  The large plan is time consuming to use as it is currently designed.  Making it larger would only place an unreasonable burden on men who might not need to spend additional time and effort taking an even larger number of pills.

4.  The large plan is expensive at the current level.  Expanding the number of therapies would only prevent men from affording the higher cost of entry.

Stay focused with that large plan; you will be busy.   TRH

18 year old wants help determining if he has Peyronie's disease

I am 18 years old and need help figuring out if I have peyronie's disease. My penis first started curving to the left about 1 and 1/2 years ago. It was only slight so I wasn't too worried. About a week ago it curved a little more to the left and now I'm worried that it's going to get more severe. Since I was a kid (long before I had any curvature) there was always a slight lump on the right side of my penis. I believe it has gotten slightly larger recently. Do I have peyronie's disease? How do I stop it from curving more? And does masturbation cause it to curve more? If you could please help me out I would greatly appreciate it, I'm really stressing out over this.


Given your history of a longstanding childhood penile mass in someone who is currently 18 years of age, I strongly encourage you to consult with a urologist about your situation.  Since your penis curve is aimed to the left and you say your lump is on the right, those two findings do not seem to correlate; this is not typical of Peyronie's disease.  But is is not possible to confidently tell you if you have PD or not based on the limited information.  This is not the kind of problem you should attempt to figure out on your own.

If you have not told your parents or some adult you trust about your problem, now is the time to do so.  You do not have to go into great detail.  Just say, "I have a urinary problem and I think I should see a doctor."  If you are pressed for details, and you are uncomfortable giving any, you can always say, "I am really uncomfortable about this, and I would prefer to discuss this with a doctor."  Any reasonable adult should respect your right to privacy.   

Put aside any embarrassment you might feel and allow a medical professional to determine your diagnosis. Getting yourself examined to determine exactly what is happening to you would be the wise and mature thing to do.  Please let me know what you are told.   TRH 

Is there a specific treatment for Peyronie's disease that occurs after a prostatectomy?

My PD occurred nearly four years ago after a laproscopic prostatectomy.  What is your opinion about the efficiency of your treatment after such a delay?   Is there a specific treatment for Peyronie's disease that occurs after a prostatectomy?  Thanks, John 

Greetings John,

Peyronie's disease is a fairly common reaction that can occur as a result of trauma to the urethra during a laproscopic prostatectomy.  I have discussed this bad result in another area of the PDI site, Possible Peyronies Cause: Catheter and Cystoscope Trauma

Many men start their PDI treatment plan three and more years after the onset of their problem.  Actually, it seems that many men begin PDI treatment three to five years into their PD problem.  At this time I have not noticed any great difference in the effectiveness and end results of those who have a late start or an early start working to increase their ability to heal and repair the PD scar.  What seems to be a more important factor for overall success of treatment is the level of faithfulness to the treatment plan and the diversity of treatment; those who follow a large and aggressive therapy plan and do it without deviation are usually most successful.       

There is no special or different treatment for Peyronie’s disease based on how it occurred.  Your treatment would be the same regardless of how it started since it is the scar that is the important aspect of Peyronie's disease treatment regardless of how it actually started.  To get an idea how to start, click on Peyronies Treatment Help Starts Here.

Do you think using vitamin E by itself will help my Peyronie's disease?

Greetings Doctor,

My urologist recommended taking 400 I U of vitamin E daily when he first told me I had Peyronie's disease, although he was not too specific about the quality or type of vitamin E I should use, or anything else for that matter.  Before he ran out the door he did not say what the next step would be if that did not help me, but he did stress that I should return in six months for another visit. 

Thank you for the helpful information about vitamin E on your Peyronies website.  At least I know now how to do it, and I will get mine from you so I know I will be taking the best vitamin E for this purpose.  I will try my doctors recommendation of just using vitamin E by itself and keep my fingers crossed.  Do you think using vitamin E  by itself will help my Peyronie's disease?   Paul

Greetings Paul,

No, I do not.  Vitamin E for Peyronies treatment is great, but it needs a lot of support from other kinds of therapy to get the job done.  And finger crossing has nothing to do with successfully treating your Peyronie's disease.  

Success is based on hard work, determination, dedication and focus to a broad based Alt Med plan that will increase your body's ability to heal and repair the Peyronie's scar.  I suggest you do all you can during these next six months to learn about your PD and the process of natural correction. The PDI treatment protocol has a high degree of success when it is done correctly.  The problem is that many men try to bastardize the PDI treatment protocol to save a few bucks, or is too lazy to do what is required, or is always looking for the easy way out.  I trust you are not that way.

Go ahead and follow your urologist's idea of using vitamin E as a solo therapy.  I have never heard of anyone who has been successful with this idea – and neither has your urologist.  He is just telling you to do that because that is what the text books tell him to say and he cannot get into trouble for repeating what is accepted current medical thinking. What is probably on his mind is that at your next office visit in six months he will be able to follow the same current medical thinking and tell you that you need Peyronie's surgery because the vitamin E did not work. They have a great thing going for themselves. 

I suggest you spend a little time on the PDI website educating yourself about the non-drug and non-surgical treatment of Peyronie's disease.  If you need any more information please let me know.  TRH     



If you miss a treatment dose does it matter?

Hi Doc,

If you miss a dose with either a therapy product that should be taken with a meal, or 1-2 hours before or after meal, does it matter?  Can you make it up?

Thanks for all your help.  



Greetings Bud,

Sure it matters. Can you make it up? No, not really.

So don’t forget.  That is what I mean when I say, “Stay focused.” You will get out of this what you put into it.

It does not take too long to learn that following an aggressive Peyronie's treatment plan is work, and it can be boring.  believe it or not, this is what makes some men so down on treating their PD that they quit after a few weeks.  Do not be one of those men.  TRH 

Should I add Neprinol to my Peyronies treatment plan?

Hello doctor,  My bottles of Fibrozym and Nattokinase from my first order are almost finished.  I am already beginning to see my scars getting smaller and softer so I am really encouraged.   You had recommended replacing these two with Neprinol when I reorder my other therapy products.  Is this the best time for that order of Neprinol, or should I reorder Fibrozym and Nattokinase and also add Neprinol to my plan.  Thanks,  Larry


Greetings Larry, 

You are very early in your care and you are already seeing some positive changes, so I will assume that more change and progress is possible once you determine the best therapy plan for your particular problem.

Everyone must work to figure out what is the best therapy plan for himself.  I suggest you should think about doing this, based on your response to your current strategy: try using only Neprinol for awhile, and see what happens.  Experiment a bit and see what happens. 

Take the Neprinol in a slowly increasing dosage based on the general information you receive when you order from PDI. If taking Neprinol as the only enzyme therapy causes your positive changes to regress or slow down, then it is a mistake and you should go back to Fibrozym and Nattokinase – but it really should make a greater improvement. If taking Neprinol as the only enzyme therapy causes further positive changes, then stay with that for a while.  After a month or two of good changes on Neprinol only, then continue using Neprinol but add Fibrozym and Nattokinase back into your plan so you are taking three enzyme products. See what that does to your scar reaction.

EVERYTHING gets back to how your scar responds. You and I can make up all kinds of treatment strategies, but you must test any of them against what they do to your scar.  It does not make any difference what you and I think might be helpful to reduce the PD scar.  You must prove to yourself that what you are taking is working by actually measuring positive changes in your PD scar.  This is the PDI treatment philosophy that makes sense to everyone.   

Your scar is the enemy – destroy it – and it will tell you exactly what it will take to do the destroying if you know what to look for in scar behavior.  However, you must be paying very close attention to what it is telling you in order for you to learn from it.  TRH

How often should a person with Peyronies use DMSO?

How often should a person with Peyronies use DMSO?  Can you use it daily with other topicals?   Will the stuff you put on after DMSO still go on?   Online it says put to put DMSO on LAST.  What if you put the DMSO on first is it still effective?


Based on the basic nature of your questions about DMSO (how often to use it; combining it with other topical therapies; frequency of application) I have the sense that you have not gotten your DMSO from PDI.  Anyone who buys from PDI knows the answers to these questions and more.  PDI provides specific information and details for correct use with all the PD therapy products we sell.  We help you every step of your journey so you get the best results you can; you would not have these questions if you were dealing with PDI.  And this brings me to my biggest concern about you…

Some men make the mistake of using the highest concentration OF DMSO they can find, thinking that stronger is better and it is not.  You cannot use effectively use a high concentration DMSO for PD treatment very long without it quickly irritating the delicate skin of the penis.   This is why PDI offers the PMD DMSO brand of DMSO that was formulated in cooperation with Stanley Jacobs, MD, the man who in the late 1950s did the first medical DMSO research on humans.   Our DMSO formula has the best concentration for PD treatment, and it also contains PABA, MSM and urea for added benefit.  No other DMSO product is made specifically for Peyronies treatment but our PMD DMSO. 

Lastly, I must mention that you need to be very careful what you combine with DMSO when it is on your skin.  You mention applying "stuff" with DMSO.  This concerns me.  I have had contact with many men who decided to experiment by applying all types of chemicals along with DMSO over their PD scars.  Some men have crushed up and diluted drugs, applied solvents, slats and hormones and added DMSO to their experiments.   All of this can be extremely dangerous and counterproductive.  Please do not experiment with DMSO in this way.     

Now that I have had my say about DMSO in general, here are the answers to your questions:

DMSO can be used up to three times daily. 

It can be used daily with other appropriate safe topical therapies. 

It is best to apply DMSO last if you are also using other topical therapies; if you apply DMSO first there will still be reduced transfer of those topical therapies you applied first.     

Is it normal for the flaccid penis to change texture?

This may be a silly question, but here goes. Is it normal for the penis in the flaccid state to change texture. Sometimes my penis in the flaccid state is soft and long and sometimes its as hard as a rock and short.  Is the scar tissue causing this?


You pose your question asking about the flaccid state of your penis presenting different textures, and present your observations that seem to be contradictory. 

You mention one state is soft and long, and the other is hard and short.   This last description sounds very much like an erection that is  shortened because of the inability to lengthen due to contraction of the penile soft tissue, and not another state of a flaccid penis.  It is not consistent to say that you are both flaccid and hard as a rock.   For the most part, you are either soft or hard, flaccid or erect, but not at the same time. 

The erection process is complex and the presence of the Peyronie's plaque or scar, a foreign mass of collagen tissue situated within the erectile tissue, can created some unusual reactions and alternations of the usual erection a man can experience.

I think perhaps what you are confusing is the lack of lengthening of your erect Peyronie's penis with still being flaccid.  TRH

Question about Peyronie's treatment

Dear Sir,

I M.A. Mujeeb from India is suffering from Peyronies. Up to May 2010 I was quite well in sex but May or June 2010 onwards my penis is bending from both side (stem side and ring side) While incursing I am getting pain. I request you to tell me whether this medicine is effective for the above problem for me.

Thanks and regards,



Greetings M.A. ,

Any or all of the different Peyronie's therapies found on the PDI website can be successful when combined in an aggressively and faithfully applied treatment plan.  The likelihood for that success is increased by following a broad based plan that includes both systemic, topical and external therapies.

Even if you did mention several therapies there is no way for anyone to intelligently predict the outcome of your use of any therapy.  Treatment results is far too complex, with far too many variables, to give a meaningful answer to your question if you could be helped.  It is always something that each man must attempt to learn for himself how he will respond. 

To assist you I suggest you read at least a few of these articles:  Peyronie's disease treatment frequently asked questions and  Peyronie's treatment philosophy and Peyronie's disease natural treatments: introduction.  





Is it possible my Peyronies scar is like a piano wire?

Dr. Herazy, I wrote you last month and you really helped my confidence with what I am doing. Is it possible that my PD scar is like a piano wire from the base to the head? That is the only irregularity I can find. Thanks Dick R.

Greetings Dick,

Yes, it is certainly possible that your scar feels like a piano wire. The Peyronies plaque or scar material presents in a wide variety of ways, just as most everything about PD seems to be variable. 

Although you did not say so, I will guess the long ridge of scar material tissue you say feels like a piano wire is located on the top or dorsal surface of the shaft.  This is a very common location for long narrow PD scars.  It is the anatomical structure, called a septum, where the tunica albuginea of the two chambers meet in the mid-line, and it runs from the base of the penis to the head (glans).   This septum is especially susceptible to separation during trauma, and can consequently develop a long thin scar.  

You can assume this is your only, or your primary, Peyronie's scar if your curved penis is directed upward.  

While you might be correct that it is only as thin as a piano wire, I suggest that you examine this thin ridge again to determine if you can detect that it tapers down to a flat band.  Almost like the gable roof of a house, your piano wire structure might just be like the uppermost ridge of the roof that gets thinner as it slopes down laterally.  I mention this speculation because it is always beneficial to have a clear and accurate visualization of each scar so you can closely monitor it  for changes as you continue to treat your PD. 

You might find, if I am correct, that this flat tapered surface on either side of the piano wire will undergo changes in size, shape, density and surface features as your scar deteriorates as your treatment progresses. 

If you do not know it is there, you will not have this useful information available to you to guide your treatment.  You must try to know everything there is to know about each of your Peyronies scars.


Do you think this is a bad idea?

Can you tell me what you think of using DMSO and possibly vinegar since it contains acetic acid, i used it and it didn't hurt but the mixture got very warm to almost hot, and it wrinkles the skin, i got this on a website… Wikipedia and other sources say….Diluted acetic acid is also used in physical therapy to break up nodules of scar tissue via iontophoresis. So can't you use dmso to deliver the acetic acid in vinegar similar to iontophoresis to break up peyronie's plaque? Do you think this is a bad idea to try?



Yes, I think this is a bad idea.  You got lucky that you only felt a hot sensation and that it just wrinkled your tissue.  I suppose had you left the vinegar on longer, or used it a second time, or in some other way increased your exposure to it, you would have probably developed a deep and serious burn of the penile tissue.  Do you know what would have been the likely result of a burn-injury to the deeper tissue of the penis for someone who already has Peyronie's disease?  More Peyronie's disease. 

Acetic acid of vinegar is a dangerous acid that will affect different tissues of the body in a variety of ways. The thin tissue of the entire genital region is unusually vulnerable to a burn injury caused by acetic acid.  When it is combined with DMSO the damage can be even more severe. 

Please do not do use vinegar again this way for your Peyronie's disease.  TRH  

How can I correct a congenital penis curvature?

Hi, i have had this problem. My penis are bent to the left and i have no pain or stress when i do the self ejaculation. But i am in a big confuse that i can marry or not? Its happen by born. What i do to get rid from it?


If your penis has been bent to the left since birth, it is not likely you have Peyronie's disease.  You probably have what we call a congenital penis curvature, or a small variation of your body that makes you different from other men.  

You ask if you should marry.  I do not know the answer to that question.  I also do not know if your penis is bent too much for you to be unable to complete the sex act. 

Keep in mind that when a woman has sufficient sexual stimulation her vaginal muscles will relax greatly, and she will produce a significant amount of lubrication.  As a result she will be able to open her vagina to allow entry of even a bent penis.  In your case, it all depends on how much you are bent and how much she can accommodate to allow entry.  That is something you will not be able to answer until you try.  

You ask how to get rid of your problem.  Many men with a congenital penis curvature have used the Peyronie's Disease Institute Manual Penis Stretching Method to reduce their curvature.  Although the method I developed was designed and researched to be used for Peyronies treatment, it apparently also helps me born with a bent penis. Again, you will not know if or how much this will help you until you try.  TRH

Looking for helpful Peyronies treatment information

I am seeking any information I can get that is helpful.

Thank you,



Greetings Susan,

The PDI website is huge.  Men have told me they attempted to print out the whole website, only to stop after 500 pages with still hundreds of pages to go. 

With that kind of information about Peyronies treatment readily available, what more can I offer to you?  A good place I send a lot of people is How to Start Peyronie's Treatment .   Just follow all the links.   

If you have a specific question perhaps I can answer it.   TRH

Do you suggest SSKI (potassium iodide) as a Peyronies treatment?

Do you suggest using Potassium Iodide (SSKI) as a Peyronies treatment online shows good results from using iodine for scars?


Yes, there is information online about using SSKI (potassium iodide) for treatment of Peyronie’s disease.  That information comes from the website of Jonathan V. Wright, MD of the Tohoma Clinic. He has some interesting things to say about it.  He is an intelligent and provocative author. I like Dr. Wright's work. 

However, concerning the work of PDI, there is a problem with the idea of using SSKI for PD:  Dr. Wright is the only one saying it. 

His concepts and opinions might very well be correct, and SSKI might be the best therapy imaginable for PD.  But I doubt it.  Why?  Because, from what I can determine, there has been absolutely no research or study of SSKI for treatment of PD or DC by anyone at any time.  It is all conjecture and theory, even if it is interesting and might make sense, it is still unfounded at this time.  It is a far more unfounded idea than anything you will find on the PDI website.  

The intent of PDI is not to present all Alternative Medicine therapies for your review simply because they are non-medicinal in nature.  We do not advocate Peyronie's therapies simply because they are “natural” or easy to acquire without a prescription.  Those therapies you find on the PDI website are there because of research (often a lot of it) that supports the use of that particular Alternative  Medicine therapy for PD, in spite of the contradictory research.  We take the position to only use those therapies that have satisfied an adequate percent of researchers to suggest the possibility of therapeutic efficacy.  If taken as a group, in aggressive doses and high combinations, these therapies stand a good chance of creating sufficient synergy to initiate a healing response to correct the Peyronie's plaque. 

SSKI does not fall into that description.  It has not been studied.  When it is studied and receives a positive review from several independent sources we will likely consider adding it to the lineup. 

Keep reading Dr. Wright’s articles, he has a lot of good information for all of us.  TRH


Should I continue with the same Peyronies therapy and for how long?

On 4/15/11 I suffered a trauma to my penis during sex, (no black and blue or bleeding), my girl leaned too far back while on top. I went to the urologist 2 days later experiencing pain and a lump at the base. He suggested 4 weeks of abstinence. Unfortunately that didn't work and I searched the internet for some answers. I am 47, of good health, exercise regularly, no health problems. I did the enzyme therapy,Vita-E and C, PABA and applied the Thackers formula every night. It has been 3 months now and no change in the lump at the base. I have an hour glass shape, no bend. The only change was the pain subsided within the first 2 weeks but the lump only changes size when erect it's larger and smaller while flaccid. This has been constant since the beginning. Should I continue with the same therapy and for how long? Please reply with any suggestions.



You ask for suggestions:

1. While abstinence might have been wise during the very acute stage of injury, it is poor Peyronie's disease treatment.  I suggest ice and anti-inflammatory measures (essential fatty acids, aspirin, etc) would have served you better.     

2. I do not know what you mean when you say you "did enzyme therapy, Vita-E and C, and PABA."   That does not tell me enough; you need to provide dosage, frequency or timing for how how you used them.  That makes a tremendous difference for the possibility of success.  Just popping pills in hopes that something works is usually not helpful and it is definitely not the way PDI suggests anyone conducts good therapy.  I cannot comment on the kind of treatment plan that you followed without knowing more about it.  I suggest you provide more information.

3.  Further, it appears that while you got your idea for using vitamin, E, vitamin C and PABA from the PDI website but you did not get your therapy products from PDI.  This is often a mistake since you have no assurance about the quality of those products or how to use them.  People who visit the PDI website for a few ideas and then experiment on their own with only partial compliance to our ideas, usually earn partial results.  I suggest you made a big mistake by deciding to experiment when you should have been actively treating yourself with known products of high quality.

4.  When you say their is no change in the lump at the base of your penis, what do you mean?  What is the current size, shape, density and surface features of that lump?  If you do not know the specific answer to those questions, I suggest you are only guessing if your lump has or has not changed.     

5.  You say since the time of your injury the lump changes size when erect compared to being flaccid, but you also say you were not black and blue as a result of the initial injury. This seems to be contradictory. Since I am not able to verify this information, I would suggest that you might be mistaken on this point. 

6.  You ask if you should continue your therapy and for how long.  You did not tell me enough about your therapy or your lump so that I can answer that question. Please provide those details. 

7.  Based on the information you provided, you "did enzyme therapy, Vita-E and C, and PABA." for about two months.  That is a short time for whatever you did.  I suggest you are being too hasty judging the effectiveness of care.  This tissue is often slow to respond.    

8.  I suggest you might not have Peyronie's disease at this time; you might be on your way toward it but you might not have it at this time. You notice I used the word "might" three times in that last sentence.  This is because I am unsure since your injury happened less than four months ago, and you did not present your story in a way that is typical of Peyronie's disease. My guess is that you are still in the acute stages of a soft tissue injury and that you should consider doing more to reduce the active inflammation at this time.  

9.  My last suggestion is the most important:  Learn more about the correct Alternative Medicine treatment of Peyronie's disease by spending more time reading about it in the PDI website.  

Good luck to you.  TRH

Does this mean I have Peyronies?


In previous questions someone asked below "how do I find my PD scar?"



In your answer you stated: "…….it is important to know your scar is not located on the surface; it is located below the surface and cannot be seen……"

I have been informed that I have Peyronie's disease, however my erections are 100% straight.  They are just less flexible and half the top surface of my penis feels very hard, because of the scar tissue.  When my penis is flaccid and erect I can easily always see the scar tissue.

Does this mean I have peyronies, also does this mean the scar tissue is just below the external skin and not on the actual erectile tissue? Is this possible? I have spoken to you previously but I am not sure if I mentioned this.


If you have been medically diagnosed with Peyronie's disease, what you say does not give me reason to doubt that diagnosis.  

After reading your entire question several times I am unsure what you mean when you say "I can easily always see the scar."   If I were to try to hide a ball under the blanket on my bed, it would still be "seen" because of the way the ball would push up and distort and wrinkle the blanket.  I would not be able to see the ball directly, only able to see the effects of the ball on the blanket that is above it.  Is this what you mean when you say you can see your PD scar?

By definition the Peyronie's plaque or scar is not located on the top surface of the skin.  It is located within the layer of tissue called the tunica albuginea that is located well below the surface of the skin, by many millimeters.     The tunica albuginea is sitting right on top of and is in contact with the actual erectile tissue, making it anatomically impossible to directly see the Peyronie's scar.  

I have communicated with many men whose PD scars are so thick and dense that they distort the skin above, and thus they can see the outline of scar that lies below.  TRH

Does DMSO cause infertility?

Does DMSO have any long term side effects i.e does it affect fertility in any way?



There are no reports or studies that connect the use of DMSO and infertility in humans whether related to Peyronie's treatment or other health problems.  There are reports of veterinary medicine using DMSO to treat infertility in horses and dogs related to fibrosis of tissues that are a part of the reproductive system.   TRH

Question about prostate surgery and Peyronie's disease

After having an open transvesical prostatectomy on Jan. 2011 my husband, 62 years old got Peyronie's disease.  We would like to know if he can take PABA and what is the best plan treatment for him considering the fact that he suffers from essential hypertension, has two stents, smoker, and is taking daily:atenolol 100mg, disothiazide 25mg, simvastatin 40mg, acetylsalicylic acid 100mg,perphenan 4mg.

Thanks for your help.

Rachel and Benny

Greetings folks,

It is not uncommon to develop Peyronie's disease after prostate surgery.  You an read some of these ideas in my post, "Possible Peyronies Cause: Catheter and Cystoscope Trauma."

Considering your husband's medical history and the amount of drugs he is now taking, I suggest that  you tell his treating doctor you would like to try a combination Alternative Medicine nutritional approach to see if he agrees with doing a few things to increase his immune response.  Many MDs are open minded in this way, and perhaps you will get cooperation from your husband's doctor.  Personally, I see no reason to think that PABA and a few other therapies would be a problem; but first get the doctors approval.  TRH     

What is the difference between DMSO in gel and liquid form?

Online the PDI site says your DMSO LIQUID is more effective than the GEL. I fear the topicals I use won't penetrate as deeply if i were to use the liquid? How is effectiveness different?  Thank you.


Both the gel and liquid format are effective in their own way, depending on what you want to accomplish. Read DMSO in Peyronie's Therapy.

We have determined that the DMSO liquid penetrates faster than the gel, but not only a little faster.   And we have determined that the DMSO gel penetrates deeper and carries more therapy agents with it.  For this important reason in 2009 PDI converted both the Dusa Sal DMSO (Dupuytren contracture) and PMD DMSO (Peyronie's disease) products to being made with a gel base.  It makes sense to sacrifice a little speed of penetration to gain depth and amount of therapy delivered to the tissue involved.   TRH

What are the exercises to make the penis straight?


i want to know what are the exercises to make the penis straight.  i have a curve about 40 degree in my penis.  i am not sure that i have Peyronies disease…thanks a lot


First things first.  You should have your curvature examined by a doctor and your condition diagnosed so you know what you are dealing with. That is important, so please do it.

I think you are a bit confused about your exercise question.  I am not aware of any exercise that can be done to reverse the bent penis of Peyronie's disease. 

PDI has two different educational CDs, an exercise video and a stretching video. The exercise CD is called PDI Massage and Exercise CD; it explains how to increase energy and increase blood and lymphatic flow in the lower pelvis.  The stretching CD is called  Peyronie's Disease Institute Manual Penis Stretching Method©; it explains how you can lengthen the contracted tissue of the penis and so straighten it.   TRH    

What is the success rate of PDI Peyronies treatment approach?

I am curious, what is the success rate of your Peyronies treatment approach? John from Australia

Greetings John,

You ask about PDI Peyronie's disease treatment results. All day long I send emails to men from around the world – like yourself – who do not have to report back to me, and over whom I have no control as to how, if, and when they use their various therapies.

I can only tell you this directly about the treatment results I have heard about from men over the years: I receive about 12-15 emails or telephone conversations reporting improvement in scar size, shape or density, or favorable change in penis curvature, or improvement of sexual function, for every one email or telephone call I receive complaining of no progress concerning the above. Considering that people tend to complain more than they compliment, I interpret this 12:1 ratio in a very favorable way.  But to give you percentages of natural Peyronies treatment improvement, I cannot report that to you at this time. Perhaps some time in the future when we are able to do formal research.

PDI is not yet conducting controlled studies, so I have no way of knowing how any of this is being used. And of course how these products are used determines the results that are earned. I get back bits and pieces of information from men about their treatment results. My feedback is limited in response to the large amount of information I put out to the PD community.

There is no guarantee that you or anyone else will use any of these products as I suggest that you use them. Actually, after doing this work since 2002 I find that few people start out using their Peyronie's treatment plan in the correct way.  You know how people can be. I can only hope that the suggestions I make are given fair consideration and application is made in the correct way. As a result, I do not receive with any regularity reports from men about their treatment results.

All I can tell you is that the more that a person does to knock that scar out of the tissue, the greater the synergistic effect and the greater the likelihood for success. You either understand the concept of synergy or you don’t. It is the reason that MDs have so much trouble with patients when they start putting them on more than one drug – when combined, the synergistic effect of multiple drugs begins to magnify, often causing drug reactions that most people have come to be concerned about. In the area of Alternative Medicine the results tend to be beneficial.

I notice from your records that you have only ordered Scar-X from PDI, and nothing else to treat your PD.   It is a good product we have used with success over many years. However, since you order only Scar-X you are using this product in a way it is not intended to be used.   You are a good example of what I mentioned earlier.  You are not following the suggestions of PDI and yet you will judge PDI results after not following our suggestions.   It is your decision; I can only advise you along the way and you will decide how you wish to proceed.  TRH

What can I do to make sure my penis curvature continues to straighten?

Greetings Dr. Herazy,

I've had Peyronies for close to 4 years. All I heard from those sad guys on the PD forums was that there is nothing you can do to cure PD.  But after being on your large PDI treatment plan for less than two months both my wife (a nurse) and I can tell there is a huge improvement in the curvature of my penis.  Not only is my bent straighter, I can enter her easier and we both have less pain during sex.  What can I do to make sure my Peyronies changes continue?   G.H.

Greetings G.H.

I am concerned here. Do not make any changes to your plan until you are fully versed in how to evaluate your progress via evaluation of your scar(s).  Judging your progress by positive changes in your curvature is all well and good, but it is not a reliable or accurate way to determine progress. Do not make the mistake of evaluating progress of your Peyronie's treatment plan solely on the basis of your reduced curvature. That is not the way you should do it. 

You must evaluate your treatment progress based on changes in the size, shape, density and surface features of your scar(s). Peyronie's disease is all about the scars, remember.  If you get rid of the scars your penis curvature will go away, but if your penis curvature gets straightened without change to your scar then the curvature will only come back.  

You must learn how to evaluate the scar for progress. I have a whole chapter devoted to this subject in my 1st book, “Peyronie’s Disease Handbook.” If you do not do your evaluation this way you are only guessing about progress and therefore you cannot determine correct dosage levels. Get the book if you do not have it. If you already have it, then re-read Chapter 4. 

Once you have a firm description of your PD scar then you will be able to use it as a reference point or benchmark to guide necessary changes in your treatment plan.  

Congratulations on your improvement so far, if you follow my suggestion I think you will be pleased how easily you can continue making good progress over your Peyronie's disease.   TRH

What are the best two choices to treat Peyronies?

Hi again.  Between PMD DMSO, Super CP Serum and Unique E oil what are the best two choices to treat Peyronies?   How do I go about using them?    Monty


Greetings Monty, 

You are asking a question no one can answer.  You must apply these therapies to yourself to learn exactly which is most effective for you.  The PMD DMSO is always used because it will bring the other two deep into the tissue; therefore the choice is between the Super CP Serum and the Callisto oil.  Because of the low cost, most men use all three of these.

From your question it is obvious you are trying to approach Peyronies treatment from a minimal standpoint, and this is doomed for failure.  You must treat PD treatment aggressively and with a broad approach.   Also, using only external therapies (PMD DMSO, Super CP Serum and Unique E oil) only is also not a good idea; you must also use internal therapies (vitamin E, vitamin C, MSM, PABA, acetyl-L-carnitine, etc.). 

How any or all of them is actually used is provided when you receive your order.  You are given everything you need to be successful.  TRH



What can PDI do for my 20 year old Peyronie's disease?

hi, what can your method do for me and my 20 year old pd that started because of a sex accident?  bill 

Greetings Bill,

Thanks for the question.

Since you have given me no details of your problem, I can only answer with generalities. The longest standing PD case with which I have been involved was a fellow who had it for 12 years. You see, most of the men I work with are usually in the 18 month to 3 year time range with their Peyronie's disease.  I think this is so because the average person who has dealt with PD for several years tends to just give up on himself and his situation, and assumes there is nothing out there for him.  The MDs eventually convince them to stop trying to get help because they do not have any drug for Peyronies treatment, and that is a shame.

Folks like you usually are not looking for help and answers – unfortunately.  But in the early phase of PD, a guy will really burn up the Internet wires looking for answers to his unsettling predicament. Having explained all that, it is my opinion that based on the favorable changes in the 12 year PD problem I worked with, and several others in the 3-8 year range I have worked with, your 20 year old problem stands as much a chance to improve as these others.

A long time ago I learned to never doubt the ability of the body to heal.

Many men, and myself, were able to get back all lost dimensions and eliminate any detectible scar formation, so I know it can be done. I assume you have just started to look at the large PDI website. Bear in mind what we propose is really different in the past in two important ways:
     1. Synergy – grouping several therapies together at the same time.  If you are like most men who go the medical route, you probably used synthetic vitamin E for a short while and then did some POTABA or verapamil drug use later.  PDI approach is different because we advocate a combined treatment approach with many Alternative medicine therapies.
     2. Quality and quantity of Alternative Medicine
most men do not appreciate the need to hit these two factors fairly hard. I can guide you in this respect to perhaps a better conclusion than you had in the past. In addition to a few vitamins, we also propose several other concurrent therapies for your PD that you have not used. These are very important to achieve the desired end result. The more you do, the stronger your synergy, the greater your odds for some success.  If you want to broaden your thinking about Peyronie's treatment with natural methods see natural Peyronie's treatment.

If you want some help to do this right, and I assume you do, send some specific questions about treatment.  PDI has a different website from anything else you will find anywhere because we have a reasonably optimistic attitude and track record with this problem, and because we actually know and care about men who have this lousy problem. I am retired now from active practice, and since overcoming and curing my own Peyronie's disease, I have pretty much devoted myself to this cause in appreciation and gratitude for the gift that was given to me.

When you are ready to do something good to help yourself, let me know.   TRH

Where is DMSO gel applied?

Dr. Herazy,

My order arrived last week, and today I started the treatment.  I'm very upbeat that I made the right decision. I have carefully reviewed all the documentation and explanations that came with my order.  It is very impressive how well you prepare your customers to work with their Peyronie's treatment products. 

The one item that I'm most confused about is the PMD DMSO gel.  Exactly where is this gel applied?  My instructions say that the topical therapies should be applied over or on top of the location of the Peyronie's plaque or scar. I do not have any scar. I don't have a problem shaving as described but I do not have a scar either on the part to be shaved or the penis. Or, when they mention scar, do they mean the part of the penis that is abnormally hard?  Please advise.  Randy


Greetings Randy,

Actually, if you have Peyronie's disease you do have a plaque or scar.   However, the scar is not external or superficial, it is internal and below the surface. It is located under the skin surface and within the tissue of penis called the tunica albuginea.  The scar or plaque is not visible from the surface; you cannot see it.  The closest you can come to actually seeing it is if the scar is so large and thick that it raises or elevates the penile skin above it and you can see the raised lump of tissue because of the large scar below the surface.  

In order to be successful you really want to get to the point that you know the size, shape, density, and surface quality of your scar(s). If this is a new concept to you, I suggest you get the 1st book I wrote “Peyronie’s Disease Handbook.” It will help you immensely.

Scar location is sometimes a complicated topic, especially in the case of multiple scars or plaques. You can expect to find at least one scar at the point of greatest concavity of your distortion. Again, this is a topic of such concern and importance that you really should get at least that one book so that you know what you are doing in regard to monitoring your scar. The physical change in your scar is going to guide your therapy; it will direct you to the best use of your therapy plan. to assist you with this subject, please go to Difficulty Finding the Peyronie's Plaque.

To answer your question about where to apply the DMSO gel and related external therapies, they should be applied directly over the area of Peyronie's plaque or scar.  You do not need to apply these external therapies to the entire shaft, unless, of course, you have a wide spread pattern of scars over most of the penis.  TRH    

What can I expect from POTABA in my Peyronie's treatment?





Greetings Bob,

In my opinion you should do a bit of online readying about POTABA. I think you will find a lot of controversy and reports of non-effectiveness about it.  From my experience there are fewer and fewer MDs using POTABA in the last few years because of high cost, limited results, and poor compliance because most men find they cannot tolerate the severe abdominal pain it causes even with the initial usage.  I am surprised your urologist did not mention this to you; I am sure he knows all about it. 

Did you ask the urologist what kind of success rate he has with this prescription?   I would be interested to know his response.

POTABA is one of the limited number of drugs available for prescription by an MD in the treatment of PD, although there are many MDs who do not prescribe POTABA  because they find the trouble their patients encounter while taking it does not justify the limited potential benefit.

Now, POTABA is nothing more than a simple B vitamin – PABA – that has a molecule of potassium added to it, or to say it another way, POTABA is a potassium salt of PABA.

PABA has been shown years ago in medical research to be successful in treatment of PD, but the medical profession likes to use drugs (POTABA) whenever it can, and refuses to use something as simple as a B-vitamin.  POTABA causes a host of gastric symptoms, for which reason few men complete their course of therapy with it.   PABA works just as well, and has no side-effects.  However, neither PABA or POTABA produce results as good as PABA when combined in a more aggressive therapy program as you see presented on the PDI website.

You should know this is a rather limited course of therapy.  No one can predict whether it will help you or not, you must follow if for a while to determine if it will improve the size, shape, density or surface quality of your Peyronie’s plaque.   You would be wise to get the book I wrote, “Peyronie’s Disease Handbook,” about dealing with Peyronie's disease on a daily basis to improve your chances for recovery. 

The Peyronie's Disease Institute has offered PABA to its visitors since 2002 for treatment of Peyronie's disease without a single report of inability to use it because of gastric problems.  To learn more about successful Peyronies treatment  TRH


Is there someting I am missing about Neprinol?

Dr. Herazy,

It is my understanding that Neprinol contains everything that the Fibrozym and Nattokinase supplements contains and is more potent, thus making it redundant to add Fibrozym to a program that already includes Neprinol.  Am I missing something?


No, some men want assurance they are not missing anything in their Peyronies treatment plan, and they intentionally use the redundancy of getting the nattokinase and serrapeptase from two different sources.

Men use Neprinol both ways – as a total substitute for the other enzyme products, or in addition to them (usually with the Neprinol being the primary enzyme source and the others being used as a minor role).  The choice is yours. When I successfully treated my own scars that is what I did – I used the Neprinol as the primary and largest supply of systemic enzymes, and then added in a few of the others per day.  

I would consider trying just the Neprinol by itself, and see how it works for you and your scar.  If that is not enough to get your scar to change favorably, then bring back the Fibrozym or Nattokinase, or Quercetin/Bromelain if you are also using it, or all of them.  You must keep experimenting to learn what makes your scar respond favorably and then continue with that.   TRH  

Does anyone know the best treatment for Peyronie's disease?

Does anyone know the best treatment for Peyronie's disease? I want to know how do I cure myself in the fastest way I can before this problem ruins my life and pushes me over the edge.  My doctor does not seem to care at all how this problem is affecting me.  He actually told me to do nothing for six months, and then he would decide if I needed surgery. I really need to know how to get back to feeling like a normal man again.


Before I give you the best and most honest answer I can, I want you to know that I had Peyronie's disease and cured myself of it in 2002.   That is how this website got started and how all of this information was put together.  When I first developed Peyronies I felt really terrible inside just like all men do when they lose this part of their lives.  I know how rotten and scared you are feeling because I felt that way and so did hundreds of men I have worked with over the years.  Many of us, just like I did, were thinking the same terrible black thoughts you are thinking right now.  You cannot let yourself lose control of who you really are and what is really important in life.  You must not let PD win over you because you are more than just a penis, and you are stronger and more important than this problem.

Every week I get emails and phone calls from men from around the world who are making improvement with their PD scars and their curvatures.  Some get a little help, some get a tremendous amount of help, but almost everyone who works hard and follows a few simple ideas about Peyronie's treatment earns some level of improvement of this PD. 

You will not know if you can help yourself until you decide to try.  Right now you are letting PD control your thoughts and feelings, and this is not good.  You are making the mistake of allowing yourself feel like a PD victim.  Just because your MD did not spend time talking with you and did not have answers for you does not mean you cannot take care of yourself.  You can be in control of your situation if you make that decision.  It all comes down to deciding to be bigger, stronger, tougher and more determined than your PD.  Once you do that you will be in control of your feelings and you will get busy helping your body eliminate your Peyronie's plaque to the best of your ability.

This will not take you more than 15 minutes:

1. Read Peyronie's Disease and a Man Whose House is on Fire.

2. Read Peyronie's Treatment Options.

3. Send me an email with your phone number.  I will call you and we can talk about anything you want to talk about.


Peyronie's treatment safety issue when applying moist heat

Hi Dr. Herazy,

The use of an electrical heating pad was suggested in last month's Peyronie's Disease Institute newsletter for the moist heat therapy. I am curious as to whether or not the immense heat and warmth provided by this electrical pad would be detrimental to the testicles. The pad it hot but does not seem hot enough to scald the penis. Thank you! 


To reduce possibility of excess heat being applied to penis and testicles you should:

     1. Reduce heat setting on the control of the heating pad so that the heat is not "immense" but only comfortably warm
     2. Place a small moist wash cloth between your skin and the heating pad to act as a buffer or spacer, thus reducing heat to the penis
     3. Position yourself so that your testicles are not in contact with the heating pad
     4. Place a dry wash cloth between the scrotum and heating pad to act as a buffer or space, thus reducing heat to the testicles

This suggestion for using an electric heating pad was submitted by one of the PDI Warriors and was presented in our last newsletter as an alternate way to apply moist heat to the shaft of the penis.  The original method that has been suggested by PDI is to use a hot water bottle wrapped with a moist towel and positioned to heat the shaft of the penis.  This method has the safety advantage of staying warm for 15-20 minutes before slowly losing heat.

Thank you for your observation.  TRH

How do I know if I have Peyronies disease?

Doctor,  Can you tell me how do I know for sure if I have Peyronies?  I went to my family doctor urologist last week because my penis started to bend to the right 2 months ago and it hurts.  After being in the room with me for less than 3 minutes and not even touching me, he said he was not sure if I have Peyronies so he told me to come back in 6 months to see if it gets worse.  It is driving me crazy not knowing for sure what is happening. Do I have PD or not?  Please help.  Carl


Greetings Carl, 

Sorry to learn of your problem and the difficult situation you are in. 

Unfortunately, no one can diagnose a condition as complex as Peyronie’s disease solely on the basis of the limited information you have provided.  While in your description there are certainly aspects that sound like you have PD, there is no way to say with any certainty without a direct examination.  

Typically, there are three primary criteria that must be fulfilled in order to establish a diagnosis of PD:

1.    Presence of one or more scars or nodules felt under the skin of the shaft

2.    Pain during erection

3.    Recent development of bend or significant distortion 

It is possible to make a diagnosis without one of the above, if the other two are strongly affirmative.   My advice is that if you are in doubt about the condition affecting you in this way, you should go to a urologist specializing in PD, or at least one who says he has considerable experience in this area, and ask him these same questions.   Do not allow another doctor to get away with the poor care that has been provided to you previously.

You deserve to have the peace of mind that comes from knowing exactly what it is that is affecting your health in this way.  

Good luck to you and let me know what the answer is to your question, please.  TRH

How do I find my Peyronies scar?

Hi, I'm twenty four and I think I got Peyronie's disease from an accident when I was in my early teens. It is naturally the most annoying thing I have to deal with. How do I find my Peyronies scar? Also, the medications and vitamins you are selling, how often would one need to replenish the stock?



Knowing where your scar is located – although not always easy or obvious – is essential to Peyronie's treatment.  Knowing your scar location and how to accurately describe it is not a matter of curiosity; you MUST know about the scar in as great detail as possible in order to know if you are making actual progress or not with your Alternative Medicine treatment.   If you do not know this, then you are guessing.

Before I go into this subject in some detail, I must remind you that the PD scar is best located while the penis is soft or flaccid – meaning not erect.  This will be true 99% of the time, so don’t bother to look unless you are flaccid. Also, it is important to know your scar is not located on the surface; it is located below the surface and cannot be seen.  Lastly, as a general statement the major scar you have that is causing a penile distortion will be found on the concave side of that distortion, usually at the lowest point of that concavity.

This problem of being unable to locate the PD scar is so common I wrote a blog post titled, "Can't find Peyronie's plaque or scar."  Check it out for more help.

PD “scars” or plaques are quiet variable.  Some men have an obvious scar and others could not find one if their life depended on it.   Often, when a scar is not found, but there is still pain and bending or any kind of recent penile distortion, a diagnosis of PD can still be made.  This is so, because the scar that is causing the pain or bending is either:

1. So small – it cannot be found

2. So very soft – it blends into the other tissue and cannot be detected

3. So deep – it cannot be reached or felt easily

4. So large and flat – that the edges are not easily determined, almost like trying to find the edge of a roll of plastic wrap.  When it is a large scar – as many of them are – it is something that is so close to you that you do not see it because you are looking far away and cannot see what is under your nose

5. So greatly different than what you think it is going to feel like that you miss it only because it does not meet your image of what it will be like

6.  The doctor’s lack of ability, experience or concern when he does the scar examination – that he simply misses what is actually there if he was better at this kind of thing – yes, I know, it is difficult to imagine but it is true.

Usually, when a scar is NEVER found it is because of a combination of two or more of these factors – deep and small, or soft, large and flat, or deep, soft and doctor error, and so on.  From my experience with those who have an extremely difficult time locating their scar, it seems that #4 (so large and flat) or #5 (so different than what you expect) are the reasons for failure to locate the scar.  Keep this in mind when you search your landscape trying to locate the scar. 

Ultimately, if you have PD you must begin the search with the attitude the scar is there, and it is only waiting to be found.  Do not start with a negative attitude; you want to have a sense of high anticipation that it will be found within the next few seconds – this will help keep your senses alert.  You should use as many different tactics as you can to find your scar(s) because having a good knowledge of your scar situation will help your treatment effort. 

Hint:  Try to think in terms of your scar being much larger than you have previously imagined.  Allow yourself to mentally expand the size of the scar you are looking for.  Meaning, if you were looking for a “pea” before, start looking for a “peanut” size structure or even larger.  This changes your methods and your outlook about what you can detect.  

It seems that lately I have many men reporting that their scars are as large as the length of the shaft, and some are narrow while others are wider.  Image that your scar is that large.  If you are looking for a pea-sized scar it will prevent you from easily finding something much larger like a postage stamp.     

Do not be discouraged if the scar you have is large since it does not seem that the size has much to do with difficulty or time required to eliminate it.  Larger scars can take just as long as smaller scars to treat.

Try this:  forget about finding a “scar.”  Just try to find something – anything – within the mass of erectile tissue that feels unlike the other tissue.  Find something that is unlike the rest of the tissue.  When you find it, mark its location with a marker pen or something that will stay on the tissue for a day or two.  Go back each day to that area and re-think what you are feeling.  You are trying to see if it becomes easier to make sense of it.  It could be that you have an unreasonable expectation of what a “scar” should feel like, and you are missing what is really rather obvious only because your expectation is wrong.  Really, how could you know what a PD scar feels like if you have never had to do this before?  It is a common problem.

I have worked with well over a thousand men with PD, some mild and some severe cases, some just a few months and several that were more than 10 years old.  I had a pretty bad PD problem until I cured my condition using the procedures found in the book I wrote and the same Alternative Medicine ideas as on the website.  You will not feel like a victim once you start working to improve your health and immune response against the presence of this foreign tissue.

There is no clear answer to your question about how often one would need to replenish the therapy that is being used.  Some therapies need to be resupplied every month or so, some every three months or so, and some never need to be replenish.   As a general idea about replenishing your therapy supply, the average man spends about $90-110/month replenishing his medium size PDI treatment plan.   TRH

Do you perform Peyronie's surgery?

Hello doctor!

I read your book and I am happy that the vitamins worked for you!

My husband has Peyronie's disease the last 2 years. He saw 2 doctors and they just recommended surgery,

Do you perform Peyronie's surgery? If you don't, could you please let me know which one is the best surgeon?

Thanks so much



Yes, the PDI treatment concept worked for me and for many men who followed the concepts you see on this website.  I assume the great majority of men who have been helped to regain their freedom from Peyronie's disease were also told they needed surgery, just like your husband.  They resolved their PD problem by using Alternative Medicine treatment and did not need surgery.

When you go to a surgeon you will usually find that they tend to think of and recommend surgery.  Since I am not a surgeon and I philosophically prefer to first use natural conservative means before resorting to drugs or surgery, I suggest before considering any type of risky surgery that your husband should first attempt a few months using Alternative Medicine to correct his problem.   TRH   

Is there any penis surgery procedure you could recommend?


I must admit that I am very embarrassed to send this message.

I'm 52 years old with what could be a fairly long 4.5 to 5" penis, but the curvature is painful and very very frustrating for my lover and me. I keep my pubic hair shaved to give the appearance of more mass, but he is not satisfied, nor am I.

Is there any penis surgery procedure you could recommend? I have been too embarrassed to mention this to our family practitioner (female).

What first steps can I do to improve my condition?

In His name, Peter


Greetings Peter,

After reading your email a few times I am not sure if you are more concerned about the pain and distortion of your Peyronie's disease, or by your loss of penile size since you developed PD. 

We live in a strange culture in which personal self-worth and value as a human being is based on penis size.  Your penis is attached to you; you are not attached to your penis. Think about that a bit. 

There is no need for embarrassment since developing PD is not a personal character flaw or a deliberate act that suggests an imperfection of who you are as a person; it is just an unfortunate  health problem.  No one should feel embarrassed for having glaucoma or asthma, not should you feel that way because of your PD.

From my experience in communicating with many hundreds of men since 2002 about penis enlargement surgery, I hear far too many horror stories of failed surgery.  Learn to enjoy what you have and who you are, or you might be left with little to enjoy.

If you want to actually treat your real problem I suggest that your go to the PDI website at Start Peyronie's Treatment to learn how to increase your ability to heal and repair your Peyronie's disease – which in turn could result in return of lost penile length and girth.   TRH

Is it adviseable to needle the penis directly?

Dr. Herazy,

I am an acupuncturist treating a patient with Peyronie's disease.  I bought your "Peyronie's Disease Handbook,"  hoping you had included specifics on the use of acupuncture, especially whether or not you think it's advisable to needle the penis directly?  I know you advise to not cause additional injury to the penis, but needling near scar tissue on other parts of the body is not contra-indicated, but actually beneficial.

What are your thoughts on this please? My patient is willing to try anything.

Greetings Doctor, 

Yes, needling a superficial scar on other parts of the body is very often beneficial, but the penis is a different part of the body. I would not needle the penis for concern of puncturing the tunica albuginea and further extending his Peyronies problem.  My concept is never to puncture the tunica in an attempt to help this problem. 

However, local treatment has always been an important part of my acupuncture practice, such as the famous Circle the Dragon technique, and that is why I advocate heavy use of the Genesen Acutouch pens to treat the PD lesion in this particular way because it will not risk injuring the patient by avoiding compromise to the tunica.

If you feel required to needle, distal points are always advisable. I do not treat a lot based on Five Elements theory, but I believe you would likely benefit your patient by evaluating for an Excess Wood situation.  Bear in mind that the “Peyronie’s “scar” is not a scar in the traditional sense of being a superficially located skin lesion; it is below the subdermis and within the tunica so the standard methods of needling a scar – that I have done daily for over 35 years – does not apply to PD.  At least, that is how I understand it based on my concept and methodology in guiding Peyronie's treatment.

If you feel obligated to needle, distal points are always advisable such as SP3, SP6, K3, GB34, the master points of the Conception Vessel, Sedation points for the Wood element and and Stimulation points for the Fire element. as well as appropriate Eight Extraordinary Meridian points (Du Mai, Chong mai, Yin Wei mai, etc.)    TRH  

Am I cheating on my wife?

Greetings Dr Herazy, 

I was wondering.  Since my penis has been bent over 70 degrees for the last few years of my Peyronies, my wife and I are not having any intercourse.  During this time, every now I have been masturbating without my wife's knowledge.  Am I cheating on her? 


Greetings Paul,

No, you are just keeping the pilot light burning for her benefit later. 

You owe it to her to be less shy and more creative.  You know, you are not the only one that needs sex every now and then. She is probably feeling lonely and neglected.  I encourage you to include her in your private efforts and maybe you two can share some favors. There is a world of sexual adventure and satisfaction for a married couple outside of traditional intercourse.  I go into all these areas in my book "Peyronie's Disease and Sex."   Don't be so selfish.  

The important goal is to get over your Peyronie's disease so you no longer have this limitation.  Stay focused on your PD treatment, please. TRH  

How do I get the DMSO gel to stay on?

How do I get the DMSO gel to stay on?  It's so viscous it won't spread out on it's own.

Tom. U.

Greetings Tom,

Never been asked that question before. My guess is that because DMSO “freezes” somewhere around 62 (?) degrees Fahrenheit, that this might be your problem. If the place where you are keeping it is rather cool, it might simply be close to turning to a solid.

I suggest you simply place it in a container of warm – not hot – water to allow it to come to its normal liquid state. The DMSO gel should have the consistency of  liquid hair shampoo. Be sure that the DMSO is the last thing you apply to the area if you are also using Super CP Serum and Unique-E oil to the shaft.   TRH

Why is it you do not offer any guarantee?

I have Peyronies disease now since I discovered I was getting a bent penis in November last year. My doctor prescribed potaba but it has done nothing in almost 4 months of treatment and in fact it seems to have got worse. I also am taking vitamin e and c that I got from the health food store but again it has done nothing.

My penis is bending sideways and upwards and seems to have an indent underneath at the head of the penis. All very upsetting psychologically also.

I found your web site and read your treatment options.  Why is it you do not offer any guarantee of your treatment?


Greetings Alex,

You must be using the correct vitamin products in the correct way to gain a positive response.  Just because you got your vitamin E and C from the health food store does not mean that they were good products.  It is estimated that over 25% of vitamin and herbal supplements sold on the open market do not contain what the label says. Many have inferior grade synthetic products.  Not all vitamin E products are created equal, and many are not what they say they are. If you are using an inferior product (without knowing it) you will not get good results. That is why I strongly encourage any one who wants to treat his Peyronie's disease with Alternative Medicine products to get them from PDI for a few reasons:

  • High product quality – these are the same products I used when I successfully treated my own PD problem
  • Great prices and discounts
  • Fresh products since PDI is the largest buyer of several of the products we sell
  • Proven effectiveness – results since 2002
  • Consultation about your treatment – I cannot discuss your treatment, or answer your questions, if I do not have experience or confidence in outside therapy products

Using only vitamin E and vitamin C is a very limited and poorly designed Peyronie's treatment idea.  I have never heard of anyone getting results with that kind of plan.   These two vitamins are great products and serve an important part in many of the plans we use, but they cannot do the total job to eliminate the PD scar. I would never suggest to anyone to try using only only vitamin E and vitamin C as you did.   

Most men who go about using their own ideas and get their own products like you are doing make very little progress with their Peyronie's disease problem.  This is a complicated and difficult problem.  You will have to admit you are guessing at a lot of what you have done and your are experimenting on yourself at a time when you should be actively treating yourself.  On the PDI website we provide a tremendous amount of free services and information like this constantly updated Q&A section and a Peyronie's treatment forum, along with private emails to men from around the world. We make these resources available to men to support their effort to correct their own PD.  If you work with the PDI system of treatment I can assist you when ideas, information and suggestions based on my experience; you will not be working alone.

You ask about a guarantee.

Who do you know in the healthcare field who offers a guarantee for any procedure or therapy? Aspirins do not come with a guarantee.  Jock itch spray does not come with a guarantee.  Toothpaste does not come with a guarantee.  Foot supports do not come with a guarantee.  Surgery does not come with a guarantee.  No one in healthcare offers a guarantee because of the complexity and difficulty of what we are attempting to do.  Everything in health care is completely unpredictable.   When you go to your dentist and he puts some Novocain in your gum, during your dental procedure he will ask you frequently if your mouth is still numb, right?  He has to ask you if your mouth is numb because he cannot guarantee the Novocain will work for you, or if he got enough in your tissue, or if he put it in the right location, or if it is not wearing off sooner than it should.  Nothing in health care can be guaranteed. 

Only people who are trying to fool you offer a guarantee for their unscrupulous products.  I see many international companies ( like in Pakistan, India, Romania) who try to sell secret herbal products and guarantee results in 30-60 days.  I hear frequently from men who bought those pills, got no results, and got no response from those companies when they tried to get their guaranteed refund.  

Be very suspicious when you see some treatment offered with a guarantee especially for Peyronie's disease.

If you are interested in trying to help your body heal the Peyronie's scars, please let me know.   TRH 

Can I use the PDI manual stretching technique to cure my curvature?

Hi  Doctor,

I have a normally bent penis with a downward curve.  I have it from when I was a child.  There is no pain, just normal curve 30 degree.   Can I use the  PDI manual stretching CD to cure my curvature ??



Many men have a curved penis from birth; it is part of what makes you a unique person.

I have had reports from men who have used the manual penis stretching technique to safely and permanently change their normally curved penis.  You can read more about the CD that explains in detail how to use this special technique at Peyronie's Disease Institute Manual Penis Stretching Method©

Keep in mind that your bent penis is a normal condition for you, even though it is 30 degrees.  Your improvement might be less than complete straightening, or it could be complete, there is no way to know ahead of time until you try it.   Please let me know how it goes for you.  TRH 

What is my opinion of prescription drug injection?

What is the Dr's opinion on using the prescription Edex injected with a syringe? 

Bryant from Ohio


Greetings Bryant, 

You ask for my opinion about Edex injections.  I will not comment on the drug, because that is the decision of your treating doctor.  But I will make a few observations about injections in general and how they could further injure the tunica albuginea.

Anytime you inject ANYTHING – even sterile water – into the penis and directly or indirectly contact the delicate tunica albuginea, you are taking a serious risk of making your Peyronie's disease worse. This could either occur just from the simple act of piercing the tissue of the tunica albuginea, or the placement of a concentrated chemical that is foreign to that tissue, or both.

I have communicated with many, many men whose Peyronie's disease started or was made worse from penile injections of a variety of substances.

If your problem is PD, why are you taking an ED medication? Some MDs prescribe Viagra, Edex, etc to their PD patients in the belief that this increases the local circulation which in turn is beneficial to PD.

What if you could take a drug that would enable you to lift a ton of weight above your head and keep it there for an hour? Nice trick, very impressive, but your body is not built to take that kind of pressure. It would cause great damage to internal organs, your spine, your blood vessels, all major joints, etc. Simply put, “It just ain’t natural.” Same with Viagra, Levitra or Cialis. The increased pressure created by these medications can be very damaging to the delicate tunica albuginea, and can result in or worsen a case of PD. What would happen to your car tires if you happened to over-inflate them with 100 pounds of air pressure, even though they were built to take just 40 pounds of pressure. You would be running the risk of damage to the internal structure of tire, wouldn’t you? Of course.

The same thing can happen if the penis is over-inflated and then given a “rough ride.” This is where the problems start, and this is what I wanted to bring to your attention. It is very likely that the MDs who prescribe these medications to men with PD will not agree with this thinking. MDs tend to favor a chemical “fix” even if it is temporary, so you would tend to expect a prejudice from an MD to use drugs to solve most problems.

A penis that is predisposed to PD in the first place cannot tolerate the kind of stress that these erections drugs create.  If you think independently and logically about what happens when these drugs are used, you should have no trouble understanding how this could work against you.  That is just the way I see it and I feel compelled to share this rationale with you. Use of Viagra and other related meds like it could easily be worsening the very problem you are attempting to heal. Something to think about.  TRH

How do I help my husband deal with his Peyronie's disease?


My husband was diagnosed with Peyronie's disease a little more than two years ago but is not doing anything about it.  His doctor told him there is nothing to do for his condition  except surgery, so he has just shut down.  He will not talk to me about his severe curvature and he refuses to discuss how we are going to continue like this.  In fact, over the last few months he is talking to me less and less.  We have not had intimate relations since all this started. 

Of course I am worried about his physical condition, but I also see him becoming more isolated and quick to get angry and this makes me worried for him.  He is a good man and we had a great relationship before this happened. 

I see that your attitude and approach is so much different about this problem that I hope you can help us.  How do I help my husband deal with his Peyronie's disease?


P.S.  Thanks for helping others.


Greetings Harriet,

Sorry to learn that your husband has withdrawn from his problem, but this is actually a very common situation.  Many men respond this way when they develop Peyronie's disease.  I know so because I receive emails all the time from worried wives that report the same thing you are going through. Peyronie's disease can be very stressful and confusing for the man who gets it, but also for his wife who desperately wants to help and does not know how. It can hurt a lot.

This subject is broad and deep.  In fact, because it is so common and important in PD treatment I devoted a considerable portion of the 2nd book I wrote to this area of the relationship of any couple dealing with PD.  I suggest you go to the PDI website and order the book, “Peyronie’s Disease and Sex” to learn what you can do to help your husband, because there is actually a lot you can do.   I know this book will help you to understand what is going on inside him, and what you can do now to bridge the gap between you.

From considerable past experience I can tell you that his lack of communication with you, and his withdrawal from sexual contact, are all related to fear and shame.   Become more knowledgeable about Peyronie's disease; learn some of the more technical terms and concepts; learn about natural PD treatment; memorize just a few facts about PD.  The very next time you are given a natural and appropriate opportunity to mention something about PD, include some of this new technical information in your conversation.  Talk about Peyronie's disease and the treatment ideas you learned on the PDI website.  Do not talk about or mention what is going on with him.  Do not make it personal at this time; make the conversational general so he is not made to feel any more uncomfortable than necessary,   Just the fact that you suddenly know these things will tell him that you are on his side, and that you now know a few things that might help him.  Slowly draw him out this way. If he asks, show him the PDI website and show him how to explore it.

If you can make him aware that there is actually a reasonable and effective approach to Peyronie's treatment that his MD did not know about, you can give your husband a a reason to get excited about overcoming his problem.  This approach has helped save other marriages and could help you also.   

Let me know if you have any specific questions I can assist you with.    TRH

What is the daily dose recommended for Neprinol?

What is the daily dose recommended for Neprinol? Thank you.

Bill C.

Greetings Bill C.,

There are several things to say about dosage in general for Peyronie treatment, that applies to Neprinol dosage in particular

1.  The starting dosage for any therapy is often the one that is listed on the label for that product.  This standard starting point is used to see if the dosage recommended by the product manufacturer can bring about a favorable change in the size, shape, density and surface features of your scar.  Often it cannot.

2.  The ongoing treatment dosage that eventually proves to reduce the original size and shape of the scar, or soften the density, or alter the surface features of a Peyronies plaque will very often be higher than what is suggested on the label of each product. 

3.  No matter which therapy product you use, it must be taken in a safe and reasonable dosage.  All of this information is available to you in the treatment section of the PDI website.  Please read that information and adhere to it.  

4.  Dosage for any ONE therapy product that is actually going to help your Peyronie's disease is not easy to determine because you will be taking MANY therapy products at the same time.  You are juggling many balls at once and this requires some patience and the ability to keep good notes about what you are doing. 

Of course, if you are taking five different internal therapies (vitamin E, vitamin C, Neprinol, Acetyl-L-carnitine and PABA) each one must be individually determined.  An important part of your therapy plan are the external therapies you are using (Genesen Acutouch pens, gentle manual stretching, DMSO, etc.) While you do all the internal and external therapies that make up your total therapy plan you must monitor the size, shape, density and surface quality of your scar(s) to note at what dosage level changes begin in the scar material.  It is as simple – and difficult – as that.

5. No clear and specific treatment dosage numbers are offered to you since everyone uses different internal and external therapies, in addition to doing them in different ways.  In this sense, since each man is different, and each man follows a different plan, each man must determine what he must do to improve his scar behavior.

The procedure to determine scar size, shape, density and surface quality is explained in great detail in “Peyronie’s Disease Handbook.” The correct dosage of any therapy product is not determined from a chart. The chart that you receive with your first order only tells you the average range of what most men are doing. Your dosage should be what you need to take daily to cause changes in your PD scar. The dosage for you is what you learn works for you. I cannot tell you what you need to take. You have to determine that by your observation of the dose that makes the scar size, shape, density, and surface quality change. This vital information will guide your use of all the therapy products; it is the measurement that tells you if your plan is working or not. All of this is explained in great detail in “Peyronie’s Disease Handbook.”

Should I take Neprinol with other enzymes or by itself?

Hi Dr. Herazy, 

Should I take Neprinol with Fibrozym and Nattokinase, or just take it by itself?   Jerry 

Greetings Jerry,

Just so we are clear on what you are asking me, I know you are following a larger PDI therapy plan so I am confident you are also using other therapies besides the Neprinol, Fibrozym and Nattokinase you mentioned.   The way you asked your question I could get the idea you wanted to just use Neprinol by itself.  If that what you are thinking of doing, then I strongly advise against that.  I have never spoken to anyone who has earned good results by using Neprinol as a solo treatment for Peyronies.  You always want to diversify and broaden your treatment base with a variety of internal and external therapies, right?  

Men use Neprinol both ways – as a total substitute for the other enzyme products, or in addition to them (usually with the Neprinol being the primary enzyme source and the others being used as a minor role). The choice is yours.

I would consider using just the Neprinol as the only systemic enzyme, and see how it goes. If that is not enough to get the scars to change favorably, then bring back the Fibrozym, or Nattokinase, or Quercetin/Bromelain, or all of them into your existing therapy plan.

You must keep experimenting to learn what Peyronies treatment makes your scar size, shape, density and surface features respond favorably and then go with that.

What other therapies or supplements should I consider at this point?

Dear Dr. Herazy:

I just started following the medium or  "better" program for PD. What other therapies or supplements should I consider at this point?

I was thinking about the Genesen Acutouch acupuncture system. Do you think this is a good idea?

If you could give me any thoughts you may have, I would appreciate it.

Thank you for your time and care, your email was very informative.



Greetings Charles,

My suggestion is that right now you should pay very close attention to the size, shape, density and surface features of your scar, and faithfully follow your current Peyronie's treatment plan.  You should do this for 10-14 days to determine if your medium plan is able to favorably influence your scar.

if it does change your scar then all you need to do is continue with the medium plan just as you are using it until the changes of scar stop or your scar goes away. 

If it does not change your scar then you need to modify your current plan – not add to it – in some way.  With the medium plan this is usually to increase the dosage of MSM, Fibrozym, Nattokinase or Scar-X.  Then you continue for another 10-14 days to see if this plan modification was able to makes changes to the size, shape, density or surface features of your scar.    

if it does change your scar then all you need to do is continue with the modified plan just as you are using it until the changes of scar stop or your scar goes away. 

If it does not change your scar then you need to modify your plan again in some way.  You continue with this slow increase of therapy for a few cycles.  If at this point you have run out of ideas, then please contact me and we can discuss your situation.     

Yes, the Genesen pens are a great therapy for several reasons.  Probably the first is the power of these pens to treat a wide variety of problems; a book is included that lists how to use the Genesen pens to treat over 100 different conditions.  Then you have the ability to duplicate a very expensive level of treatment without incurring a great expense.  Also, you can treat yourself and your acupuncture points more often than you could afford to do so if you were going to the office of a professional.  The Genesen pens are often the difference that boosts therapy results from so-so to significant.  You might consider buying them later if it becomes apparent that you need extra help. 

Let me know how I can help you.   TRH

What is the average age for onset of Peyronies?

Greetings Dr. Ted, 

Thanks again for all the information you have provided in the past. My curve has gone from 60 degrees to less than 10 degrees.  I can't believe all this change in just 13 weeks after only getting worse for the last three years.  

One more question that I have is about my age when my PD started.  I am 36 now and I got PD when I was 33.  According to most sites you read it states that occurrence typically is after age 55+, and some even say 40+.   Although I am sure there is great variation, does 33 seem young or typical given your experience?

Thanks again,


Greetings Gary, 

No, 33 is not especially young to develop Peyronie's disease.  I, unfortunately, communicate with many men your age and even younger who have PD.  Last week I was involved in a lengthy discussion with a young man of 18 years who has had a diagnosed case of PD for almost two years. It does happen.  

Age is less of a factor in Peyronie's disease than people would like to think, and the numbers are not absolute.  Just as you have stated that many sources report that PD usually occurs in men 40+ or 55+ or whatever age you might read, that does not mean there is a wall protecting you for the next few years if you are 37 years old.  While it is true Peyronies disease is a problem of older men, you youngsters can develop it also.  I would not put too much emphasis on that entire subject of age and PD.

The real question is now that you know you have PD, what are you going to do about it?  Let me know if I can help you tweak your plan a bit more to increase the rate of your improvement.  TRH

What is the best combination of products for treatment of Peyronies?

You may not be the one to ask but what is the best combination for treatment of peyronies?  I have read and seen so much, my head is spinning. Thank you. Sonny

Greetings Sonny,

Probably a good place to start is by looking at the structure and diversity of the three Peyronies treatment plans (small, medium and large) that are shown and described at the top of the page of the PDI store

These different plans were put together so you can see how a balanced and diversified plan looks, and to make it easy for men to purchase a plan as a simple starting point for natural Peyronie's treatment.

Ultimately the best plan is the one that reduces the size, shape and density of your Peyronie's plaque.  This is determined over time by monitoring your PD scars while you are self-administering any plan you put together for yourself or have selected from the three PDI offers you.

To get to the point of your question about the "best": there is no best for everyone. You must search it out based on what works for you.

I think people come to the PDI looking for the "best" PD treatment in the same way they go to their doctor looking for the best drug to reduce their high blood pressure or the best salve for their rash.  In the PDI method of treatment we realize their is no one single Peyronie's treatment; we realize a combination of treatments are used at the same time to encourage and support the body to heal the PD plaque.  Further, we realize that this combination is different for everyone.   So each man starts out using the plan that he thinks might help him, and is prepared to modify it later if it does not make the necessary changes in his scar tissue.  This is why it is so difficult to answer the question "What is the best Peyronie's treatment?"   Each person must work that out individually.  I can help you with that process.  TRH      

Can you tell me how long the PDI middle plan will last?

Hello Dr. H,

My husband is considering the middle plan for his Peyronie’s. Can you tell me how long it will last him?

Thank you!

Karen A.

Greetings Karen A.,

Many people want to get an understanding about rate of product usage, so yours’ is a common concern.

Each person approaches his Peyronie’s disease treatment plan a little differently, not only in regard to size of treatment plan and overall direction of therapy, but especially in terms of dosage.  Some men take all their PD therapies in a very conservative way, some men take all their PD therapies in a very aggressive way, some men take 1-2 of their therapies conservatively and a few very aggressively, other men do not follow their plans very faithfully and so forget to do what they should do.

Because of this, each bottle and each therapy plan will last for a variable length of time.  In other words, not all men who get a Medium Plan use it in the same way or at the same rate.  So, how long individual bottles of any therapy plan will last is a personal and variable issue for which I can only give you approximations based on what I see others doing.

Based on my experience with others who use a PDI Medium Plan, the average person re-supplies the DMSO and Super CP Serum close to once every 3 months, while the Factor 400/400 and Maxi-Gamma E, C, Scar-X and MSM about every 4-6 weeks, and the systemic enzymes every 4 weeks.  Of course, the Massage and Exercise video CD is never replaced.  My guess-timation is that the average man will spend about $75-100 monthly to replenish the Medium Plan, after he makes his initial purchase which will be the greatest expense.  To state it another way, the Medium Plan costs around $210 to start, and about $75-100 per month to continue.     

In addition to the usual information that comes with your plan, I would suggest that you really should get the book I wrote about PD, “Peyronie’s Disease Handbook.”   In chapter 4 of this book you will learn the essential skill of how to determine the size, shape, density and surface features of your scar so that you will know exactly how to regulate your intake of therapy in your plan.  In addition, the book also gives a wealth of practical information that you can easily use every day to make life with PD easier and less stressful.  This popular book gives treatment suggestions and a dietary approach to PD that are not found on the PDI website; actually, the book is most helpful and valuable in treating PD, but in a much different way than what is found on the PDI website.  Check it out.   

Good luck to you and your husband.  Let me know if I can help in any way. TRH



Why is acetyl-L-carnitine not mentioned on your website?

I'm wondering why is Acetyl-L-carnitine not mentioned on your website for treatment of Peyronie's disease?  I have read some really strong research findings about acetyl-L-carnitine and am eager to try it out.  

Thanks, Bruce

Greetings Bruce, 

You are incorrect, Bruce, acetyl-L-carnitine is mentioned often. We have highly recommend the use of acetyl-L-carnitine since 2002. 

Please go to this large page on the PDI website that explains what you need to know about this excellent PD therapy,  Acetyl-L-Carnitine and Peyronie's Treatment.   For a bit more go to the PDI store to read Acetyl-L-Carnitine and Treatment of Peyronie's Disease where I refer to this therapy as an All-Star product. 

To learn how to use this therapy product, and others, for ideas and suggestions to put it all together, click Create a Peyronie’s Treatment Plan    TRH

Why are two different vitamin E products made available?

Why are 2 different Vitamin E sources (400/400 and Gamma E) suggested in your therapies?  What are the differences? Would only 1 suffice in an effort to help manage costs?


Your question about the reason for the two different types of vitamin E to treat Peyronie's disease is a common one.  Thank you for bringing it up again.

I cannot put an entire detailed answer to your question in this reply. Let me just comment that the Maxi-Gamma vitamin E is used because it provides a higher ratio of the Gamma type of vitamin E that is helpful in healing and removing scar tissue.  The other vitamin E product, Factor 400/400, is a balanced vitamin E providing all eight types of vitamin E that does not emphasize the Gamma type the way the other one does.   When used together they complement each other and work nicely to provide an excellent and highly concentrated source of vitamin E that will assist your body to correct your Peyronie's disease to the best of your ability. 

To get the full answer and to learn more about vitamin E in a Peyronies treatment plan, go to Vitamin E for Peyronies treatment

Sure, if you used only one type of vitamin E it would manage costs.  But, which one to use?  I do not have a clear answer on that one because I can make a good argument for both of them as being the one you should use if you were going to only use one. 

If you must use just one, then I suggest you experiment a bit by using one of the products in your overall plan to see how you respond, and then use the other one to see if you respond differently to it.  Of course, this is how I suggest that anyone approaches any of the therapies to see if it should be included in a therapy plan.  TRH

Should my husband have a penile implant?

My husbands penis curves 90* upward when erect and has painful intercourse. We believe it's from an injury he sustained during intercourse about a year or so ago. We have seen a urologist several times and have been told our only real option is a prosthesis. Do you think your program could help us?


It is not my intention or desire to interfere between your husband and his urologist concerning any aspect of his treatment or his relationship with his doctor.  I will not answer your question directly if your husband should or should not consider having a penile prosthesis surgically implanted to resolve his current sexual problem – I have no direct opinion or advice for your question.  That is a subject for discussion between the two of you and your husband's treating doctor.  My only interest and purpose in making this reply is to offer general ideas, and pose questions to you, to broaden your discussion with the urologist about the progression of your husband's care.

My general opinion on this subject and ideas for you to consider, as you make up your own minds about his treatment, are these:

    1.  The penile prosthesis is a mechanical device that induces an artificial state of erection – either temporary or permanent –  so that intercourse can take place.  It is usually thought of a surgical treatment for Erectile Dysfunction, and less so for Peyronie's disease. Regardless of the type of penile prosthesis that is used it is necessary to surgically remove all or part of the corpora cavernosa (the bulk of the internal tissue that gives body to the penis) to make room for the prosthesis.  Once this is done the penis can never be returned to normal.  If there is some reason (massive infection, his body rejects the foreign material of the prosthesis, failure of the device) to remove the prosthesis, his penis will be just a small shell of what it once was.      

    2.  There are several basic types of prosthetic devices, and each has its advantages and disadvantages.  Which one is suitable for a patient is often determined during the actual operation when internal measurements can be made. Sometimes it happens that the patient wants one thing, but the surgeon is not able to provide that option because of anatomical problems.  The type of prosthesis to use is a huge subject and one that is very important for you to consider ahead of time.  I suggest that you go to several websites to research what your actual options are for each type of prosthesis, and what are the pros and cons of each.  Some sites you can visit are    and

    3.  While it is stated that 90%-95% of inflatable prosthesis implants produce erections suitable for intercourse, it is important to note that this must mean that 5-10% of  inflatable prosthesis implants produce erections that are not suitable for intercourse.  In my opinion for 5-10% of men to wind up having a non-functional erection after going through a gruesome surgery so they would have a functional erection, is a huge failure number.  The medical profession is proud to tell patient that the rate of patient satisfaction is very high with penile prosthesis use, and state that somewhere in the range of  80%-90% of men are satisfied with their results.  Again, I look at it from other direction and think about the 10-20% of men who are not satisfied with their device after going through the surgery.  Many people I communicate with are disappointed because of the lack of natural feel and natural appearance of the penis after surgery, the partial or total loss of sensation, the occasional or constant pain they experience, and/or the feel of something foreign in their groin area.  They must either continue to let it remain inside their body or remove it and be left with a flap of skin. 

    4.  Very few of the websites that discuss penile prosthetic surgery provide much detail about surgical failures and adverse surgical reactions. No surgery is totally free of possible direct complications, and penile implants have their own unique list of  possible complications:

  • Infection, and even recurrent infections that return long after the surgery is over
  • Uncontrolled bleeding after surgery, possibly leading to re-operation
  • Scar tissue formation, especially important in someone who already has Peyronie's disease
  • Tissue erosion and breakdown internally where the implant touches tissue, leading to eventual removal
  • Accidentally cut nerves, arteries or veins that lead to unintended consequences like pain, numbness, coldness, and/or chronic edema 
  • Mechanical failure of the prosthetic implant, leading to re-operation and removal

I have communicated with hundreds of men whose penile implant surgeries have gone bad.  Some doctors might mention post-operative infections, and even severe post-operative infections, but they do not elaborate what that really means in terms of possible long-term consequences to the patient and his partner. As a result of infections that occur, scar formation and unintentional cutting of nerves, arteries and veins the patient is left with more problems than before his penile implant surgery.  A man can be left with partial or total loss of sensation that means partial or total numbness of the penis no sexual stimulation or pleasure is felt.  He can be left with temporary or permanent pain, of a mild to severe nature, that is made worse by anything contacting the penis.  I have communicated with men whose only option after several failed penile surgeries was amputation.    

    5.  Most people who write to me about surgical options for  Peyronie's disease are considering an operation that will correct the curvature, not install a foreign device. What is the reason you were given to not do a Nesbit procedure or a skin graft?   Most often, after the Nesbit or skin graft fails only then, as a last option, is a penile implant suggested.  I am curious why in your husband's case the implant was suggested to start.  While I am not a big fan of the Nesbit and skin grafting options, they are still more conservative than a penile implant.  

    6.  It makes sense to me to first attempt more conservative options; options that do not have permanent and irreversible consequences. If this makes sense to you, you could consider spending a little time on the PDI website learning about the conservative options available to you.  You might check out Natural Peyronie's Disease Treatment.

   7.  There is no way for me to tell you in advance if the Alternative Medicine methods of PDI will help your husband.  It is something that has to be worked on over time to determine if he is capable of supporting and enhancing his immune response to eliminate the Peyronie's plaque that is causing his penile curvature. 

In college a wise professor repeated frequently to our class, "There is never a perfect situation."   As I grow older I understand the importance of keeping this in mind.  When it comes to the often imperfect nature of surgery of any kind, it is better to be conservative at the onset and gradually play out to more aggressive and potentially risky options as your conservative choices are used up – not the other way around.    

Good luck in discussing this subject with your urologist.   TRH   


Will erections further injure my penis?

Dr. I have ED, used ED meds and now have Peyronies. Have stopped the Med use but still get erections at night. Will getting erections further injure my penis ?


No, erections will not further injure your penis.  Based on your brief explanation I suspect your penis could have been injured more so by the prescription medications you were given for your ED.   My suspicion is that you were given a prescription for one of the  PDE-5 (phosphodiesterase-5, like Cialis, Levitra or Viagra) drugs.  Taking one of these could have produced an excessive reaction in which the erection caused more internal pressure than was healthy for you.  This, in turn, could have resulted in damage to the internal penile tissue and hence Peyronie’s disease. For more discussion of this subject, go to Peyronie’s disease treatment and Viagra, Cialis and Levitra and  Viagra Peyronie’s Disease Connection

If you now notice pain while erect since you have Peyronie’s disease, this does not mean that the erection is necessarily bad for you.  The erection is simply stretching inflamed internal penile tissue related to the PD.

You might also find reading Peyronie’s Disease and the Erection  to be helpful to understand this subject. 

I suggest you avoid the PDE-5 erection producing drugs in the future, since they could possibly injure you further now that you have Peyronie’s disease.  Consider investigating the non-drug erection producing herbal and mineral products that will not risk injuring your further.  They can be found toward the bottom of the list on the PDI shopping cart. TRH

Should I continue penile injections for Peyronies treatment?

I have Peyronie's disease causing a bend to the left and downwards and it's closer to the tip then the base. I have seen a urologist who has injected it twice now. I haven't seen any improvement. both my doctor and myself have trouble finding any plaque. I'm 50 and in good shape….this just showed up a couple of months ago…there was no trauma…should I continue with the injections?  .


It is not my intention or desire to interfere between you and your urologist concerning your treatment or any other aspect of your relationship.  Nor will I answer your question directly if you should or should not continue with the injections you are receiving – I have no direct opinion or advice for your question.  That is a subject for discussion between you are your treating doctor.  My only interest and purpose in making this reply is to offer ideas, and pose questions to you, to broaden your discussion with the urologist about the progression of your care.

My opinion and ideas for you to consider are these:

    1. Any time you make a simple injection into the penis with anything, even sterile water,  you are physically traumatizing the thin tunica albuginea membrane where the Peyronie's plaque is located.  Many times when these injections are given at multiple sites of the tunica albuginea at one office visit, causing multiple trauma.  Yes, these are small needle holes, but they are holes none the less.  When given at multiple sites within a small area, and done on multiple occasions, that is still a lot of trauma (think of a shot gun blast which is just a lot of small holes). Your body has already demonstrated the tendency and ability to lay down excess collagen in the form of Peyronies plaque without any trauma or trauma so small that you do not remember it, so what will be its reaction when actually traumatized?  It is my opinion that any injection is a direct injury that could possibly cause more plaque or scar tissue to develop or worsen plaque already present. 

Avoidance of the trauma of needle injection is the reason that since 2002 I have counseled perhaps 20 or so MDs (of whom 2 were urologists) who had PD and wanted to avoid surgery, injections and drugs. 

    2.  The needle injection points are not the only potential trauma to the tunica.  Since you did not mention what drug was being injected by your doctor, I cannot comment specifically on that issue, but it is my opinion any drug has a potential to cause chemical trauma in the form of an allergic reaction, side effect or perhaps just a chemical irritation to the tunica in certain individuals.  If this is the case with you, this could result in additional irritation internally and further trauma to tissue that has already created Peyronies plaque for no apparent reason you recall.  It is my opinion that any drug reaction or unexpected side effect could possibly result in additional  plaque or scar tissue or further aggravate plaque already present.  

Unexpected drug reactions and unexplained side effects are a fact of life in medical practice.  This is such a large problem that there is a medical term for it, "Adverse Drug Reactions" or ADR.  In fact, a 1999 report in JAMA of a meta-analysis entitled "Incidence of Adverse Drug Reactions in Hospitalized Patients" by J. Lazarou concluded that

             "The overall incidence of serious ADRs was 6.7% (95% confidence interval [CI], 5.2%-8.2%) and of fatal ADRs was 0.32% (95% CI, 0.23%-0.41%)
             of hospitalized patients. We estimated that in 1994 overall 2216000 (1721000-2711000) hospitalized patients had serious ADRs and 106000
             (76000-137000) had fatal ADRs, making these reactions between the fourth and sixth leading cause of death.

             Conclusions.— The incidence of serious and fatal ADRs in US hospitals was found to be extremely high."

I am not at all suggesting that any penile injection could cause a fatal reaction, but I am suggesting that if in hospitals serious and fatal ADRs occur at the rate of 6.7%, the rate of less serious ADRs must be even higher.  All of this means that drug reactions occur at a seriously high rate, you are taking drugs directly into the penis, and you are already in a position in which you should be extremely careful because your penis will probably overreact if it is further injured.   

    3.  If you say that you and your doctor have trouble finding any plaque, then where are these injections being given?  If the exact location cannot be confidently identified by your doctor, then how accurate is the placement of these injections you are receiving?

    4. It is estimated that 50% of men who begin Peyronie's disease will self-limit or cure their own problem without any outside help or medical care.  The  Alternative Medicine treatment concepts of PDI is simply to do all that you can with natural methods to increase the natural healing ability of your own immune system to eliminate your Peyronie's plaque.  How to go about doing this is the subject of the large PDI website.  I suggest that you, and everyone else with Peyronie's disease, consider attempting conservative measures before undertaking more aggressive Peyronie's treatment that has potential for side effects and drug reactions.     

Good luck in discussing this subject with your urologist.   TRH    

Benefit of VED for treatment of Peyronie's disease?

Dr. Herazy,

Do you recommend or see any benefits for using a Vacuum Erection Device (VED) for the treatment of early stage Peyronie's Disease when the patient has no difficulty achieving a normal erection by sexual stimulation?


Please review my blog post on this subject from a few years ago,

Generally, like with most things related to Peyronies, I find men saying different things about the VED; some say it helps and some say it does not and others say it caused their PD.  The greatest limitation I find is that whatever stretching of the penile tissue occurs using the VED is too general.  To do any good in Peyronie's disease treatment the stretching must occur only and specifically at the site of the scar, not the entire organ.  To do this I developed the Peyronie's Disease Institute Manual Penis Stretching Method described in this video.    

Another way to look at the subject  of the VED is in regard to the current level of injury and vulnerability of your penile tissue at this time.  You already have a problem, and the problem often starts from a very small injury – sometimes so small that it goes unnoticed.  The VED will apply perhaps up to 100 PSI to your tissue; enough to often break blood vessels and tear tissue.  This amount of force applied to the penis that already has shown a tendency to over-respond to injury by creating excess scar tissue does not sound like a good idea to me.  TRH

How to use Thatcher's formula for Peyronie's disease?

Doctor, I have one question. How does someone use Thatcher’s Formula (DMSO + Castor Oil + copper) for Peyronie’s disease? Over the last few months I have researched various PD topics I have found a few random posts about this formula and how to apply it using flannel and warm heat…if you have any more specific information, would you kindly pass it along?  Thank you for your time and information, Bill

Greetings Bill,

Yes, I know about using Thacker’s formula.  Thacker’s formula has bounced around a lot for many years in Peyronie’s disease discussion groups, and has achieved something close to cult notoriety.

The first thing you should know about Thacker’s formula is that it does not contain copper.   It contains, DMSO, castor oil and apple cider vinegar.  It is essential that you do not use this therapy, or any other, based upon what you pick up here and there on the various Peyronie’s forums where many untested and untrue ideas are promoted – like the notion that Thacker’s formula contains copper.

My suggestion to you is to first use a well balanced and aggressive Peyronie’s therapy plan such as you see on the PDI website, while you carefully monitor your scar for changes in size, shape, density and surface features to give evidence to your progress.   Our PDI therapy plans have been used since 2002 with success and are based on reasonable science and positive research findings.  This makes more sense to me than using Thacker’s formula by itself.   I would agree that you should consider using Thacker’s formula along with other therapies in a combined effort, just as we recommend combining other PD therapies for best effect.

Please let me know how I can help you during your therapy effort.  TRH

Too late for help after Peyronie's surgery?

Dear Dr. Herazy,

My husband developed Peyronie's disease almost seven years ago after an injury while making love. His urologist first did a series of injections with verapamil. When that did not help he talked us into surgery by saying that it was the only way to straighten his 90 degree curvature. The surgery went very badly and now his curvature is worse and he has no feeling in his penis. He has become withdrawn and is very angry with himself and takes it out on me. i am so glad to have finally found your non-drug website and only wish we had found it sooner before the surgery. Do you think it is too late for my husband to get help from your alternative medicine treatment ideas?

Thank you.

Marge V.


Greetings Marge,

Sorry to hear of your husband's bad reaction to surgery. 

There is no way I can answer your question directly, since there are far too many unknowns and variables.  However, I can tell you that many men who have had bad Peyronie's surgery results have seen a reduction of scar tissue after following a PDI treatment plan; some of these changes were very small and some were remarkably great.  The work is always long and difficult because of the complications of additional scar tissue, but always worthwhile for any reduction of numbness and reduction of other problems such as curvature and pain that can occur.  There is no way to tell ahead of time if your husband is capable of any change in his scar tissue, but if some can be made it could result in some degree of improvement of his current sad situation. 

I suggest that you get both of my books and that you and your husband read them, especially "Peyronie's Disease & Sex." 

Go slowly with your husband and do not push him too much to follow any of these ideas,  He is angry and scared about injuring himself more with any kind of additional treatment, and most of all he is embarrassed.  Give him some room to warm up to the ideas of safe Alternative Medicine care.  If he has any questions or hesitation please encourage him to email me directly.  I will try to help him as much as I can.    TRH

Do I need your book or a doctor?

Thanks Doctor, I’m 64 and do a lot of heavy exercise. Yesterday I got a hard-on ….and for the first time time there was a break (left bend in the bottom third of my penis).  Do I need your book or a doctor? Thanks. Mike Adler


Greetings Mike,

What you really need is to know for sure what is going on with that bent penis.  The best way to do that should be to go to a doctor for an examination and diagnosis.  The problem is often that the doctor does not know, does not want to take the time, or does not seem to care about dealing with Peyronie’s disease.  Even after a medical examination it is common for a man to still be unsure if he has a correct diagnosis. 

To help you along this line of thought I suggest you read two blog posts that I did a while back.  The first is  Disorders of the penis besides Peyronie’s disease. This will give you an idea of what other problems you could be dealing with that could cause the sudden bend in your penis.  The second is Who is a Peyronie’s disease expert?.  This will give you some insight about the medical visit to have your penis examined. 

I suggest that you get a very good medical examination or at least in some way come to a point where you are confident with the condition going on below your belt.  It is not always easy, however, so be prepared.

If you wish to learn more about treating PD I urge that you start with the book I wrote, “Peyronie’s Disease Handbook.”  It will ground you so you know how to deal with PD from a physical and mental standpoint, treatment concepts, how to develop the essential skill of determining the size, shape, density and surface features of your Peyronie’s plaque, and how to avoid doing things that can cause additional injury to yourself. 

Let me know if I can help you in any way. Good luck.  TRH

Does Peyronies last forever?

Does peyronies last forever, or is their an estimate to how long it lasts? Thanks.



Here are your short answers:    Peyronie's disease can last forever, but in a large percent of cases it does not have to if the man actively and aggressively works to increase his healing ability against PD.   And, PD can last a life time in those men who do nothing about it.

In about half of the cases of Peyronie's disease, the disease will be self-corrected or eliminated without doing anything about it.  The body heals and eliminates the PD problem naturally like it heals and eliminates thousands of other health problems. jeale.  In the other half of persistent cases, the problem tends to continue indefinitely unless it is treated with Alternative Medicine methods that increases the body's ability to self-correct and heal the Peyronie's plaque.

For those men whose Peyronie's disease does not go away on its own, they tend to be very active and motivated to get help for their problem.  But after talking to a few MDs, reading a few online websites or asking a few questions on Peyronie's forums, they eventually learn the standard medical answer that there is nothing that can be done for Peyronie's disease – that there is no cure for PD.  After learning this from multiple sources they tend to get depressed and discouraged and stop looking for help.  Since they accept defeat, and never start to assist their natural recuperative abilities, their PD tends to either stay the same or slowly worsen over time.  Some men report slow gradual improvement of their PD while other men report slow gradual worsening, the opposite.  These contradictory reports of long term outcome of what eventually happens in Peyronie's disease is consistent with the extremely variable and contradictory nature of this problem.

So in this sense, I suppose you could find different opinions about how long Peyronies lasts.  Given the variable and contradictory nature of PD, most men agree that they do not want to risk that their PD will get better in 10 or 20 years.  They get active and they get started working a PD treatment plan as we discuss throughout the PDI website.  A good place to start learning about Peyronie's treatment is start Peyronie's treatment.

Dimensions of girth prosthetic rings?

The dimensions of the girth prosthetic rings are not given.

I see that this information was omitted.  Here you go:

Large ring:  2 5/8" long X 1 5/8" wide with a 5/8" opening

Small ring:  1 3/4" long X 1 1/2" wide with a 5/8" opening. 

Please bear in mind that although the 5/8" wide opening in the center of the rings is small, the material is very elastic and will stretch to fit and accommodate your particular girth and degree of curvature.  This firm hold is needed to provide lateral support against sudden and dangerous bending. 

This prosthetic device is very popular and assists to provide extra support for the bent penis to avoid additional injury, or when the penis is narrowed by plaque formation.  TRH

Age 17: Is my bent penis Peyronie's disease?

Hey Dr. Herazy, I am 17 Years old and have noticed this curvature in my penis for as long as i can remember. Ive been doing some research on different treatments for Peyronie's disease. . I was wondering what, if any, vitamins can I take that will help remove the plague or increase the bloodflow through the affected area. I want to try all of my options before I turn to surgery. And also I am sexually active but self-conscious as to what females will think when they see my PD. What should I do ?


First things first:  At the age of 17, if you have had a penile curvature "for as long as you can remember" it is not likely to be PD.  Your curvature is most likely a normal anatomical variation that makes you the unique person you are. 

No need or reason for embarrassment.  In my 2nd book, "Peyronie's Disease & Sex" I spend considerable time explaining in great detail how many women prefer a bent penis because it — shall we say — scratches their itch in a way that a straight penis does not.  In that book I counsel men that if you have a bent penis — either from PD or from a congenital variation — rather than sitting embarrassed in a corner afraid of being rejected, they should look for that wonderful woman who needs a man whose penis is bent.  Your task is almost like looking for the right lock that fits your key.

You ask what you should do.  I strongly suggest that you get to a urologist who is experienced with Peyronie's disease and get a diagnosis of what is actually going on with you.  At this point you are making an assumption, and that is not the way to approach this situation.  Do not guess about PD.  When you know for a fact you have PD — at this point I believe you do not have PD — then get back to me and I will guide you through natural treatment.  TRH 

When and how do I make changes to my Peyronie's treatment plan?

Hi again Dr. Herazy,

Just one more question. I am beginning to see changes in my scar, like softening and reduction of the scar. . What I want to know is, when and how do I make changes to my plan?

Jeffery C.


Greetings Jeffery,

Progress or lack of progress with your Peyronie's plaque is what determines when you change your plan and what changes you make to it.  As I have said so many time before, "The scar dictates treatment." 

If you are currently making satisfactory changes in your scar, do not change anything.  If you are not making satisfactory changes in your scar, you should think about making a positive change to your plan.

Do you have the 1st book I wrote, “Peyronie’s Disease Handbook”?  If you do not have it, then you will not know about monitoring your current condition.  If you have it, then you can use this information to guide you to increase or decrease your plan as your PD dictates. 

For you to know for sure that a recent treatment plan modification is effective you will have to notice some positive change in your scar (softening, fragmentation, smoother edges, etc.) within 10-14 days of the change in your plan, perhaps faster.  I would make some logical change (usually an increase of an existing therapy item or a new therapy item if your plan is small) and then wait at least 14 days before looking for a change to occur in the size, shape, density or surface qualities of your scars, before considering another change.  

In the beginning of care it might be necessary to only add or increase one therapy if you are at a lower level of therapy (just starting to take the medium plan).  In the early stages of therapy modification you will likely keep slowly adding to your plan, one therapy (only PABA or only MSM or only Neprinol only or whatever single item you decide to increase) at a time, by adding 1-2 pills per day.   It is not wise to go too quickly from one level to another (like taking Neprinol at 6/day, and then jumping to 14/day; this is too fast and you might not need to take so many for good changes to occur).  After a while, when your total number of pills is getting to a point where you might think you simply do not want to take more pills/spend more money, then at that point you might consider this a good strategy:  modify your plan by decreasing one therapy slightly as you increase another therapy slightly.  This way you are not overwhelming your system with unreasonable loads of pills and you are not spending an extreme amount of money. 

Be gradual with your changes.   Keeps good notes about your scars.  Let me know if this did not answer your question.   TRH      

Question about Peyronie's CD video

I also forgot to ask I had previously ordered the video … However I want to order the medium package but I do not need the video again…do you offer a discounted price if I do not need the video….just curious appreciate your help…Thanks


I will answer your question in two ways.  The first answer will be based on the error I think you have made in your question, and the second will be an answer as you have asked your question. 

First, based on an error I think you made:  There are actually two CDs that PDI has available.  There is an Exercise and Massage CD — that is a part of the Medium and Large PD plans.  And there is a Manual Penis Stretching CD — that is not part of the Medium and Large PD plans.  It is rare that anyone orders the Exercise and Massage CD by itself.  Most everyone who orders a CD by itself will order the Manual Penis Stretching CD.  This is what makes me believe you ordered the Manual Penis Stretching CD — which is not included in the Medium Plan you want.   You really should get and use the information in the Exercise and Massage CD because it is an important part of any good Peyronie's treatment plan.  I encourage you to get the full Medium Plan so that you will be able to go about following the treatment as you should.

Second, the way you asked the question:  No, there is no way within the way the system is set up to add a discount to an already discounted item, such as the medium plan. if you want to order everything in the medium plan except the Massage and Exercise CD (meaning the Maxi-Gamma and Integral E 400/400, MSM, nattokinase, etc)  then you will have to order them separately.  

Please let me know if I can help you with your Peyronie's treatment questions.  TRH

Do you give any discounts for repeat customers?

Do you give any discounts for repeat customers?  Thank you.


Yes, we do offer discounts, but they are available to everyone — repeat customers and new customers.   These discounts are available each time you place an order with PDI.  Some are automatic and some you must enter a discount code.

We attempt to offer the very lowest prices for our pharmaceutical grade therapy products to everyone who orders from PDI, and our sister-website for Dupuytren contracture at DCI. 

Everyone is concerned about discounts and keeping costs down lately, and Peyronie's treatment can be expensive. 

Our prices are already the lowest you will find anywhere for the high quality product line of pharmaceutical grade therapies.  Please bear in mind that not only are our prices outstanding and our products have been shown to be effective with PD when used as suggested, but our SERVICE is even better – and it is service, information and experience to help with your treatment that you must consider when you are treating your Peyronie's disease.   What you are receiving from PDI – even more than great products at a great price – is the time and effort given to you to provide the experience and insight into successfully treating your PD.   

If you decide to purchase your different therapy products elsewhere based only on price you will be using untested and unknown brands that right not actually contain what their label claims.  This is always the problem with purchasing based only on low price. 

These are the discounts PDI offers:

            1.  Standard and automatic 10% discount for all Small, Medium and Large Treatment Plans. 
            2.  TRH10 — $10 off each order of $200 or more
            3.  "neprinol" — $9.99 discount for a 300 count bottle of Neprinol 
            4.  "neprinol90" — $25.04 discount for a 90 count bottle of Neprinol

Let me know if I can help you with your Peyronie's treatment plan in any way.   TRH   

What can I do to reduce the plaque?

i am 48 years old, and have had peyronie's for approximately 5-6 years from unknown origin (but most likely from a crush injury). my condition has progressed to the point where i have a very significant plague that runs almost the entire length of my penis; the plague quite literally feels like bone, and is located more near the top of my penis (between the outer skin and urethra). my penis is not curved, but rather has shortened (fairly substantially) and has lost significant girth; while my erections are reasonably hard (though not as hard as previous to the condition), the overall size of my penis has reduced quite significantly. in addition, i seem to have lost nearly, if not all feeling in my penis, so much so that when i do have sex w/ my wife, i feel virtually nothing, where it takes me a very long time to reach orgasm, if at all. sadly, i most often fail to reach such; only very rarely am i able to achieve orgasm now. in fact, it is somewhat difficult for me to even know precisely how full/ hard my erection is unless i actually palpate such. i have recently returned to the united states (from living in china), and will now be able to resume taking a fairly substantial series of supplements recommended by you and provided from your company. what can i do to reduce the plaque, and to hopefully regain feeling in my penis? can i ever regain feeling? your assistance is greatly appreciated … eric


Greetings Eric,

Thank you for your detailed description and questions.

I am a bit confused by your description of the location of your plaque (part of your description sounds like your plaque is on the bottom/under side of the shaft and another part sounds like your Peyronie's plaque is on the top/upper surface). 

In my reply I will assume it is on the upper/top surface of the shaft as you are looking down at your erection, since this is by far the most common presentation of plaque that runs the length of the shaft. This plaque location is most often responsible for lost length and girth, such as you describe, and for generalized erectile dysfunction.  Many men with PD experience localized reduction of erectile ability, resulting in soft spots, or nicks or dents or dings in various areas of the shaft.  Yours sounds like the entire shaft is soft, often the result of plaque development within the septum of the penis (the point where the tunica albuginea that is around one corpora cavernosa touches or combines with the tunica albuginea of the other corpora cavernosa).  

Your loss of feeling is not common; most men with Peyronie's disease with have little trouble with loss of sensation.  While lost penile sensation could be due to other factors unrelated to PD, I will assume it is related to the central location of your plaque compromising your nerve supply.   If this is true, and I have no way of knowing for a fact that it is since I have not examined you, I assume that your penile sensation should return once your plaque is reduced.  Besides reduced reduction of sexual sensation, do you also notice general loss of sensation to light touch or pain (as when you pinch the skin of penis)? 

You ask what you can do to reduce the plaque.  I saw in today's list of orders that you purchased a large assortment of internal therapies (Acetyl-L-carnitine, MSM, Neprinol, Omega T, Quercetin-Bromelain, Factor 400/400 and Maxi-Gamma).   However, you did not order any internal therapies (PMD DMSO, Unique-E oil, Super CP Serum, or Genesen Acutouch pointers).  Both internal and external therapies are necessary for effective treatment.  It is also necessary that you follow the dietary modifications outlined in "Peyronie's Disease Handbook" to keep your blood pH toward the alkaline side.  The stretching video contains detailed information how to address plaque formation found within the septum, such as you have.  All of these therapies must be applied at the same time to achieve best results.    

You will probably have to modify your plan to achieve favorable changes to the size, shape, density and surface features of your plaque.  Do not be slow in making those changes to your plan when you see that after 10-14 days of treatment the plaque is not responding.  For this reason it is absolutely critical that you clearly can identify the size, shape, density and surface features of your plaque.  I know I might sound like a broken record when I continue to repeat this, but if you do not know these four aspects of your plaque description, you are only guessing at your treatment.  Please, do not guess. Know what is going on down there below your belt and you will have an excellent way to direct and guide your therapy toward the greatest degree of success of which you are capable.

Please stay in close contact with me as you begin your self-directed therapies.  Let me know of any problem or questions that arise, and I will be happy to offer you information and ideas for your consideration.  TRH

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